Development and Binocular Matching of Orientation Selectivity in Visual Cortex (Xu et al 2020)


This model investigates the development of orientation selectivity and its binocular matching in visual cortex by implementing a neuron that has plastic synapses for its inputs from the left and right eye. The plasticity is taken to be voltage-based with homeostasis (Clopath et al 2010). The neuron is modeled as an adaptive exponential integrate-fire neuron. The uploaded model has been used in Xu, Cang & Riecke (2020) to analyze the impact of ocular dominance and orientation selectivity on the matching process. There it has been found that the matching can proceed by a slow shifting or a sudden switching of the preferred orientation.

Model Type: Synapse; Realistic Network; Neuron or other electrically excitable cell

Region(s) or Organism(s): Mouse

Cell Type(s): Abstract integrate-and-fire adaptive exponential (AdEx) neuron

Model Concept(s): Development; Long-term Synaptic Plasticity; Orientation selectivity; Synaptic Plasticity; Vision

Simulation Environment: MATLAB

Implementer(s): Riecke, Hermann [h-riecke at northwestern.edu]

References:

Xu X, Cang J, Riecke H. (2020). Development and Binocular Matching of Orientation Selectivity in Visual Cortex: A Computational Model. Journal of neurophysiology. 123 [PubMed]


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