"... we consider a model of astrocyte-regulated synapses to investigate this hypothesis at the level of layered networks of interacting neurons and astrocytes. Our simulations hint that gliotransmission sustains the transfer function across layers, although it decorrelates the neuronal activity from the signal pattern..."
Model Type: Realistic Network; Extracellular; Synapse
Cell Type(s): Astrocyte
Transmitters: Gaba
Model Concept(s): Dynamic extracellular concentrations; Calcium dynamics
Simulation Environment: Brian 2
Implementer(s): Vuillaume, Roman
References:
Vuillaume R, Lorenzo J, Binczak S, Jacquir S. (2021). A Computational Study on Synaptic Plasticity Regulation and Information Processing in Neuron-Astrocyte Networks Neural computation. 33 [PubMed]