Rat phrenic motor neuron (Amini et al 2004)


We have developed a model for the rat phrenic motor neuron (PMN) that robustly replicates many experimentally observed behaviors of PMNs in response to pharmacological, ionic, and electrical perturbations using a single set of parameters.

Model Type: Neuron or other electrically excitable cell

Currents: I Na,p; I Na,t; I L high threshold; I N; I T low threshold; I K,Ca

Model Concept(s): Ion Channel Kinetics; Action Potentials; Spike Frequency Adaptation

Simulation Environment: C or C++ program (web link to model)

References:

Amini B, Bidani A, Zwischenberger JB, Clark JW. (2004). A model of the rat phrenic motor neuron. IEEE transactions on bio-medical engineering 51 [PubMed]