The paper presents models of the rat vibrissa processing system including the posterior medial (POm) thalamus, ventroposterior medial (VPm) thalamus, and GABAB- mediated feedback inhibition from the reticular thalamic (Rt) nucleus. A clear match between the experimentally measured spike-rates and the numerically calculated rates for the full model occurs when VPm thalamus receives stronger brainstem input and weaker GABAB-mediated inhibition than POm thalamus.
Model Type: Realistic Network
Region(s) or Organism(s): Thalamus
Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell; Thalamus reticular nucleus GABA cell
Model Concept(s): Simplified Models; Rate-coding model neurons
Simulation Environment: C or C++ program
Implementer(s): Golomb, David [golomb at bgu.ac.il]
References:
Golomb D, Ahissar E, Kleinfeld D. (2006). Coding of stimulus frequency by latency in thalamic networks through the interplay of GABAB-mediated feedback and stimulus shape. Journal of neurophysiology. 95 [PubMed]