The model supports the experimental findings showing that the dynamic interaction between cells with various firing patterns could differently affect GABAergic signaling, leading to a wide range of interneuronal communication within the hippocampal network.
Model Type: Dendrite
Cell Type(s): Hippocampus CA1 interneuron oriens alveus GABA cell
Currents: I A; I Sodium; I Potassium
Receptors: Gaba
Model Concept(s): Activity Patterns; Bursting; Active Dendrites; Detailed Neuronal Models; Action Potentials; Signaling pathways
Simulation Environment: NEURON
Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]
References:
Minneci F et al. (2007). Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells. Hippocampus. 17 [PubMed]