In this paper, the model was used to show how that FFI can change a steeply sigmoidal input-output (I/O) curve into a double-sigmoid typical of buffer systems.
Region(s) or Organism(s): Dentate gyrus
Simulation Environment: NEURON
Ferrante M, Migliore M, Ascoli GA. (2009). Feed-forward inhibition as a buffer of the neuronal input-output relation. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]