"The electrical characteristics of many neurons are remarkably robust in the face of changing internal and external conditions. At the same time, neurons can be highly sensitive to neuromodulators. We find correlates of this dual robustness and sensitivity in a global analysis of the structure of a conductance-based model neuron. ..."
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Stomatogastric ganglion
Currents: I Na,t; I L high threshold; I T low threshold; I A; I K; I K,Ca; I Potassium
Model Concept(s): Bursting; Temporal Pattern Generation; Phase Response Curves
Simulation Environment: C or C++ program
Implementer(s): Goldman, Mark [msgoldman at ucdavis.edu]
Goldman MS, Golowasch J, Marder E, Abbott LF. (2001). Global structure, robustness, and modulation of neuronal models. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]