GP Neuron, somatic and dendritic phase response curves (Schultheiss et al. 2011)


Phase response analysis of a GP neuron model showing type I PRCs for somatic inputs and type II PRCs for dendritic excitation. Analysis of intrinsic currents underlying type II dendritic PRCs.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Basal ganglia

Cell Type(s): Globus pallidus neuron

Genes: HCN1; HCN2

Model Concept(s): Oscillations; Synchronization; Active Dendrites; Synaptic Integration; Parkinson's; Phase Response Curves

Simulation Environment: GENESIS

Implementer(s): Edgerton, Jeremy R. [jedgert at emory.edu]; Hanson, Jesse E.; Schultheiss, Nathan W [nwschultheiss at gmail.com]

References:

Schultheiss NW, Edgerton JR, Jaeger D. (2010). Phase response curve analysis of a full morphological globus pallidus neuron model reveals distinct perisomatic and dendritic modes of synaptic integration. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]


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