A simple integrative electrophysiological model of bursting GnRH neurons (Csercsik et al. 2011)


Csercsik D, Farkas I, Hrabovszky E, Liposits Z. (2012). A simple integrative electrophysiological model of bursting GnRH neurons. Journal of computational neuroscience. 32 [PubMed]

See more from authors: Csercsik D · Farkas I · Hrabovszky E · Liposits Z

References and models cited by this paper

Abrahám IM, Han SK, Todman MG, Korach KS, Herbison AE. (2003). Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Aparicio SA et al. (2005). Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 90

Bainov D, Simeonov P. (1989). Systems With Impulse Effect Systems with impulse effect.

Bezprozvanny I, Watras J, Ehrlich BE. (1991). Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature. 351 [PubMed]

Caeser M, Brown DA, Gähwiler BH, Knöpfel T. (1993). Characterization of a calcium-dependent current generating a slow afterdepolarization of CA3 pyramidal cells in rat hippocampal slice cultures. The European journal of neuroscience. 5 [PubMed]

Campbell RE, Gaidamaka G, Han SK, Herbison AE. (2009). Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

Campbell RE, Han SK, Herbison AE. (2005). Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes. Endocrinology. 146 [PubMed]

Cantrell AR, Catterall WA. (2001). Neuromodulation of Na+ channels: an unexpected form of cellular plasticity. Nature reviews. Neuroscience. 2 [PubMed]

Charles A, Weiner R, Costantin J. (2001). cAMP modulates the excitability of immortalized H=hypothalamic (GT1) neurons via a cyclic nucleotide gated channel. Molecular endocrinology (Baltimore, Md.). 15 [PubMed]

Chu Z, Andrade J, Shupnik MA, Moenter SM. (2009). Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Chu Z, Moenter SM. (2006). Physiologic regulation of a tetrodotoxin-sensitive sodium influx that mediates a slow afterdepolarization potential in gonadotropin-releasing hormone neurons: possible implications for the central regulation of fertility. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Conn P, Freeman M. (2000). Neuroendocrinology in physiology and medicine..

Costantin JL, Charles AC. (1999). Spontaneous action potentials initiate rhythmic intercellular calcium waves in immortalized hypothalamic (GT1-1) neurons. Journal of neurophysiology. 82 [PubMed]

Csercsik D et al. (2010). Hodgkin-Huxley type modelling and parameter estimation of GnRH neurons. Bio Systems. 100 [PubMed]

DeFazio RA, Heger S, Ojeda SR, Moenter SM. (2002). Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. Molecular endocrinology (Baltimore, Md.). 16 [PubMed]

DeFazio RA, Moenter SM. (2002). Estradiol feedback alters potassium currents and firing properties of gonadotropin-releasing hormone neurons. Molecular endocrinology (Baltimore, Md.). 16 [PubMed]

Duan W, Lee K, Herbison AE, Sneyd J. (2011). A mathematical model of adult GnRH neurons in mouse brain and its bifurcation analysis. Journal of theoretical biology. 276 [PubMed]

Farkas I et al. (2010). Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons. Endocrinology. 151 [PubMed]

Finch EA, Turner TJ, Goldin SM. (1991). Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release. Science (New York, N.Y.). 252 [PubMed]

Fletcher PA, Li YX. (2009). An integrated model of electrical spiking, bursting, and calcium oscillations in GnRH neurons. Biophysical journal. 96 [PubMed]

Friedman A, Arens J, Heinemann U, Gutnick MJ. (1992). Slow depolarizing afterpotentials in neocortical neurons are sodium and calcium dependent. Neuroscience letters. 135 [PubMed]

Ghamari-Langroudi M, Bourque CW. (1998). Caesium blocks depolarizing after-potentials and phasic firing in rat supraoptic neurones. The Journal of physiology. 510 ( Pt 1) [PubMed]

Han SK, Abraham IM, Herbison AE. (2002). Effect of GABA on GnRH neurons switches from depolarization to hyperpolarization at puberty in the female mouse. Endocrinology. 143 [PubMed]

Han SK, Todman MG, Herbison AE. (2004). Endogenous GABA release inhibits the firing of adult gonadotropin-releasing hormone neurons. Endocrinology. 145 [PubMed]

Heldring N et al. (2007). Estrogen receptors: how do they signal and what are their targets. Physiological reviews. 87 [PubMed]

Herbison AE. (2008). Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V). Brain research reviews. 57 [PubMed]

Herbison AE, Pape JR, Simonian SX, Skynner MJ, Sim JA. (2001). Molecular and cellular properties of GnRH neurons revealed through transgenics in the mouse. Molecular and cellular endocrinology. 185 [PubMed]

Izhikevich EM. (2007). Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting.

Jasoni CL, Romanò N, Constantin S, Lee K, Herbison AE. (2010). Calcium dynamics in gonadotropin-releasing hormone neurons. Frontiers in neuroendocrinology. 31 [PubMed]

Kato M, Ui-Tei K, Watanabe M, Sakuma Y. (2003). Characterization of voltage-gated calcium currents in gonadotropin-releasing hormone neurons tagged with green fluorescent protein in rats. Endocrinology. 144 [PubMed]

Knobil E. (1980). The neuroendocrine control of the menstrual cycle. Recent progress in hormone research. 36 [PubMed]

Krsmanović LZ et al. (1992). Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neurons. Proceedings of the National Academy of Sciences of the United States of America. 89 [PubMed]

Kuehl-Kovarik MC, Partin KM, Handa RJ, Dudek FE. (2005). Spike-dependent depolarizing afterpotentials contribute to endogenous bursting in gonadotropin releasing hormone neurons. Neuroscience. 134 [PubMed]

Kuehl-Kovarik MC et al. (2002). Episodic bursting activity and response to excitatory amino acids in acutely dissociated gonadotropin-releasing hormone neurons genetically targeted with green fluorescent protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

LeBeau AP, Van Goor F, Stojilkovic SS, Sherman A. (2000). Modeling of membrane excitability in gonadotropin-releasing hormone-secreting hypothalamic neurons regulated by Ca2+-mobilizing and adenylyl cyclase-coupled receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Lee K, Duan W, Sneyd J, Herbison AE. (2010). Two slow calcium-activated afterhyperpolarization currents control burst firing dynamics in gonadotropin-releasing hormone neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Lehman MN, Coolen LM, Goodman RL. (2010). Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion. Endocrinology. 151 [PubMed]

Li YX, Rinzel J. (1994). Equations for InsP3 receptor-mediated [Ca2+]i oscillations derived from a detailed kinetic model: a Hodgkin-Huxley like formalism. Journal of theoretical biology. 166 [PubMed]

Maeda K et al. (2010). Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus. Brain research. 1364 [PubMed]

Mayer ML. (1985). A calcium-activated chloride current generates the after-depolarization of rat sensory neurones in culture. The Journal of physiology. 364 [PubMed]

Moenter SM, DeFazio RA. (2005). Endogenous gamma-aminobutyric acid can excite gonadotropin-releasing hormone neurons. Endocrinology. 146 [PubMed]

Morita K, Barrett EF. (1989). Calcium-dependent depolarizations originating in lizard motor nerve terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. 9 [PubMed]

Navarro VM et al. (2009). Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Nunemaker CS, DeFazio RA, Moenter SM. (2003). Calcium current subtypes in GnRH neurons. Biology of reproduction. 69 [PubMed]

Parker I, Ivorra I. (1990). Inhibition by Ca2+ of inositol trisphosphate-mediated Ca2+ liberation: a possible mechanism for oscillatory release of Ca2+. Proceedings of the National Academy of Sciences of the United States of America. 87 [PubMed]

Petersen SL, Ottem EN, Carpenter CD. (2003). Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol. Biology of reproduction. 69 [PubMed]

Rance NE, Krajewski SJ, Smith MA, Cholanian M, Dacks PA. (2010). Neurokinin B and the hypothalamic regulation of reproduction. Brain research. 1364 [PubMed]

Roberts CB, Best JA, Suter KJ. (2006). Dendritic processing of excitatory synaptic input in hypothalamic gonadotropin releasing-hormone neurons. Endocrinology. 147 [PubMed]

Roberts CB, Campbell RE, Herbison AE, Suter KJ. (2008). Dendritic action potential initiation in hypothalamic gonadotropin-releasing hormone neurons. Endocrinology. 149 [PubMed]

Roberts CB, Hemond P, Suter KJ. (2008). Synaptic integration in hypothalamic gonadotropin releasing hormone (GnRH) neurons. Neuroscience. 154 [PubMed]

Roberts CB, O'Boyle MP, Suter KJ. (2009). Dendrites determine the contribution of after depolarization potentials (ADPs) to generation of repetitive action potentials in hypothalamic gonadotropin releasing-hormone (GnRH) neurons. Journal of computational neuroscience. 26 [PubMed]

Seminara SB et al. (2003). The GPR54 gene as a regulator of puberty. The New England journal of medicine. 349 [PubMed]

Sim JA, Skynner MJ, Herbison AE. (2001). Heterogeneity in the basic membrane properties of postnatal gonadotropin-releasing hormone neurons in the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Spergel DJ, Krüth U, Hanley DF, Sprengel R, Seeburg PH. (1999). GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Stojilkovic SS, Krsmanovic LZ, Spergel DJ, Catt KJ. (1994). Gonadotropin-releasing hormone neurons: intrinsic pulsatility and receptor-mediated regulation. Trends in endocrinology and metabolism: TEM. 5 [PubMed]

Suter KJ. (2004). Control of firing by small (S)-alpha-amino-3-hydroxy-5-methyl-isoxazolepropionic acid-like inputs in hypothalamic gonadotropin releasing-hormone (GnRH) neurons. Neuroscience. 128 [PubMed]

Suter KJ et al. (2000). Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: characterization of whole-cell electrophysiological properties and morphology. Endocrinology. 141 [PubMed]

Teruyama R, Armstrong WE. (2007). Calcium-dependent fast depolarizing afterpotentials in vasopressin neurons in the rat supraoptic nucleus. Journal of neurophysiology. 98 [PubMed]

Van Goor F et al. (2000). Amplitude-dependent spike-broadening and enhanced Ca(2+) signaling in GnRH-secreting neurons. Biophysical journal. 79 [PubMed]

Verkhratsky A. (2005). Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiological reviews. 85 [PubMed]

Vitalis EA et al. (2000). Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells. Proceedings of the National Academy of Sciences of the United States of America. 97 [PubMed]

Watanabe M, Sakuma Y, Kato M. (2004). High expression of the R-type voltage-gated Ca2+ channel and its involvement in Ca2+-dependent gonadotropin-releasing hormone release in GT1-7 cells. Endocrinology. 145 [PubMed]

Watanabe M, Sakuma Y, Kato M. (2009). GABAA receptors mediate excitation in adult rat GnRH neurons. Biology of reproduction. 81 [PubMed]

Wintermantel TM et al. (2006). Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility. Neuron. 52 [PubMed]

Yin C, Ishii H, Tanaka N, Sakuma Y, Kato M. (2008). Activation of A-type gamma-amino butyric acid receptors excites gonadotrophin-releasing hormone neurones isolated from adult rats. Journal of neuroendocrinology. 20 [PubMed]

de Roux N et al. (2003). Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proceedings of the National Academy of Sciences of the United States of America. 100 [PubMed]

References and models that cite this paper

Park C, Rubin JE. (2013). Cooperation of intrinsic bursting and calcium oscillations underlying activity patterns of model pre-Bötzinger complex neurons. Journal of computational neuroscience. 34 [PubMed]

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