Calcium waves and mGluR-dependent synaptic plasticity in CA1 pyr. neurons (Ashhad & Narayanan 2013)

A morphologically realistic, conductance-based model equipped with kinetic schemes that govern several calcium signalling modules and pathways in CA1 pyramidal neurons

Model Type: Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite

Region(s) or Organism(s): Hippocampus

Cell Type(s): Hippocampus CA1 pyramidal GLU cell

Currents: I Na,t; I L high threshold; I T low threshold; I A; I K; Ca pump

Receptors: AMPA; NMDA; mGluR; IP3

Transmitters: Glutamate

Model Concept(s): Active Dendrites; Synaptic Plasticity; Signaling pathways; Calcium dynamics; G-protein coupled; Calcium waves

Simulation Environment: NEURON

Implementer(s): Narayanan, Rishikesh [rishi at]; Ashhad, Sufyan [soofy at]


Ashhad S, Narayanan R. (2013). Quantitative interactions between the A-type K+ current and inositol trisphosphate receptors regulate intraneuronal Ca2+ waves and synaptic plasticity. The Journal of physiology. 591 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.