Spreading depression model for FHM3 with Nav1.1 mutation (Dahlem et al. 2014)

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• Ion concentration dynamics as a mechanism for neuronal bursting (Barreto & Cressman 2011) [Model]

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• Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]

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• Single neuron with dynamic ion concentrations (Cressman et al. 2009) [Model]

Dahlem MA. (2013). Migraine generator network and spreading depression dynamics as neuromodulation targets in episodic migraine. Chaos (Woodbury, N.Y.). 23 [PubMed]

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• Squid axon (Hodgkin, Huxley 1952) (NEURON) [Model]
• Squid axon (Hodgkin, Huxley 1952) (SNNAP) [Model]
• Squid axon (Hodgkin, Huxley 1952) (LabAXON) [Model]
• Squid axon (Hodgkin, Huxley 1952) (SBML, XPP, other) [Model]
• Squid axon (Hodgkin, Huxley 1952) used in (Chen et al 2010) (R language) [Model]

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Schiff SJ, Barreto E, Ziburkus J, Cressman JR, Ullah G. (2011). Erratum to: The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. J Comput Neurosci. 30

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Vanmolkot KR et al. (2007). The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online. Human mutation. 28 [PubMed]

Yao W, Huang H, Miura RM. (2011). A continuum neuronal model for the instigation and propagation of cortical spreading depression. Bulletin of mathematical biology. 73 [PubMed]

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• Single neuron with ion concentrations to model anoxic depolarization (Zandt et al. 2011) [Model]

van den Maagdenberg AM, Haan J, Terwindt GM, Ferrari MD. (2007). Migraine: gene mutations and functional consequences. Current opinion in neurology. 20 [PubMed]

Hübel N, Andrew RD, Ullah G. (2016). Large extracellular space leads to neuronal susceptibility to ischemic injury in a Na+/K+ pumps-dependent manner. Journal of computational neuroscience. 40 [PubMed]

• Anoxic depolarization, recovery: effect of brain regions and extracellular space (Hubel et al. 2016) [Model]

Hübel N, Dahlem MA. (2014). Dynamics from seconds to hours in Hodgkin-Huxley model with time-dependent ion concentrations and buffer reservoirs. PLoS computational biology. 10 [PubMed]

• Hodgkin-Huxley with dynamic ion concentrations (Hubel and Dahlem, 2014) [Model]

Hübel N, Hosseini-Zare MS, Žiburkus J, Ullah G. (2017). The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization. PLoS computational biology. 13 [PubMed]

• The role of glutamate in neuronal ion homeostasis: spreading depolarization (Hubel et al 2017) [Model]

Hübel N, Ullah G. (2016). Anions Govern Cell Volume: A Case Study of Relative Astrocytic and Neuronal Swelling in Spreading Depolarization. PloS one. 11 [PubMed]

• An ion-based model for swelling of neurons and astrocytes (Hubel & Ullah 2016) [Model]

Stein W, Harris AL. (2022). Interneuronal dynamics facilitate the initiation of spike block in cortical microcircuits Journal of computational neuroscience. 50 [PubMed]

• Cortical Interneuron & Pyramidal Cell Model of Cortical Spreading Depression (Stein & Harris 2022) [Model]

Sætra MJ, Einevoll GT, Halnes G. (2021). An electrodiffusive neuron-extracellular-glia model for exploring the genesis of slow potentials in the brain PLoS computational biology. 17 [PubMed]

• The electrodiffusive neuron-extracellular-glia (edNEG) model (Sætra et al. 2021) [Model]