Large-scale neuromusculoskeletal model of human upright standing (Elias et al 2014)


Elias LA, Watanabe RN, Kohn AF. (2014). Spinal mechanisms may provide a combination of intermittent and continuous control of human posture: predictions from a biologically based neuromusculoskeletal model. PLoS computational biology. 10 [PubMed]

See more from authors: Elias LA · Watanabe RN · Kohn AF

References and models cited by this paper

Alexandrov AV, Frolov AA, Horak FB, Carlson-Kuhta P, Park S. (2005). Feedback equilibrium control during human standing. Biological cybernetics. 93 [PubMed]

Aniss AM, Diener HC, Hore J, Gandevia SC, Burke D. (1990). Behavior of human muscle receptors when reliant on proprioceptive feedback during standing. Journal of neurophysiology. 64 [PubMed]

Arnold EM, Ward SR, Lieber RL, Delp SL. (2010). A model of the lower limb for analysis of human movement. Annals of biomedical engineering. 38 [PubMed]

Baloh RW, Jacobson KM, Beykirch K, Honrubia V. (1998). Static and dynamic posturography in patients with vestibular and cerebellar lesions. Archives of neurology. 55 [PubMed]

Banks RW. (2006). An allometric analysis of the number of muscle spindles in mammalian skeletal muscles. Journal of anatomy. 208 [PubMed]

Bawa P, Stein RB. (1976). Frequency response of human soleus muscle. Journal of neurophysiology. 39 [PubMed]

Bottaro A, Casadio M, Morasso PG, Sanguineti V. (2005). Body sway during quiet standing: is it the residual chattering of an intermittent stabilization process? Human movement science. 24 [PubMed]

Bottaro A, Yasutake Y, Nomura T, Casadio M, Morasso P. (2008). Bounded stability of the quiet standing posture: an intermittent control model. Human movement science. 27 [PubMed]

Bui TV, Grande G, Rose PK. (2008). Multiple modes of amplification of synaptic inhibition to motoneurons by persistent inward currents. Journal of neurophysiology. 99 [PubMed]

Burke D, Hagbarth KE, Skuse NF. (1978). Recruitment order of human spindle endings in isometric voluntary contractions. The Journal of physiology. 285 [PubMed]

Burke D, Pierrot-Deseilligny E. (2012). The circuitry of the human spinal cord: Spinal and corticospinal mechanisms of movement.

Cabrera JL, Milton JG. (2002). On-off intermittency in a human balancing task. Physical review letters. 89 [PubMed]

Casadio M, Morasso PG, Sanguineti V. (2005). Direct measurement of ankle stiffness during quiet standing: implications for control modelling and clinical application. Gait & posture. 21 [PubMed]

Cheng EJ, Brown IE, Loeb GE. (2000). Virtual muscle: a computational approach to understanding the effects of muscle properties on motor control. Journal of neuroscience methods. 101 [PubMed]

Cisi RR, Kohn AF. (2008). Simulation system of spinal cord motor nuclei and associated nerves and muscles, in a Web-based architecture. Journal of computational neuroscience. 25 [PubMed]

Day JT, Lichtwark GA, Cresswell AG. (2013). Tibialis anterior muscle fascicle dynamics adequately represent postural sway during standing balance. Journal of applied physiology (Bethesda, Md. : 1985). 115 [PubMed]

Destexhe A. (1997). Conductance-based integrate-and-fire models. Neural computation. 9 [PubMed]

Di Giulio I, Maganaris CN, Baltzopoulos V, Loram ID. (2009). The proprioceptive and agonist roles of gastrocnemius, soleus and tibialis anterior muscles in maintaining human upright posture. The Journal of physiology. 587 [PubMed]

Dideriksen JL, Negro F, Enoka RM, Farina D. (2012). Motor unit recruitment strategies and muscle properties determine the influence of synaptic noise on force steadiness. Journal of neurophysiology. 107 [PubMed]

Diener HC, Dichgans J, Guschlbauer B, Mau H. (1984). The significance of proprioception on postural stabilization as assessed by ischemia. Brain research. 296 [PubMed]

Duarte M, Harvey W, ZatsiorskyVM. (2000). Stabilographic analysis of unconstrained standing. Ergonomics. 43 [PubMed]

Elias LA, Chaud VM, Kohn AF. (2012). Models of passive and active dendrite motoneuron pools and their differences in muscle force control. Journal of computational neuroscience. 33 [PubMed]

Eliasmith C et al. (2012). A large-scale model of the functioning brain. Science (New York, N.Y.). 338 [PubMed]

Farina D, Negro F, Dideriksen JL. (2014). The effective neural drive to muscles is the common synaptic input to motor neurons. The Journal of physiology. 592 [PubMed]

Fitzpatrick R, Burke D, Gandevia SC. (1996). Loop gain of reflexes controlling human standing measured with the use of postural and vestibular disturbances. Journal of neurophysiology. 76 [PubMed]

Gage WH, Winter DA, Frank JS, Adkin AL. (2004). Kinematic and kinetic validity of the inverted pendulum model in quiet standing. Gait & posture. 19 [PubMed]

Gatev P, Thomas S, Kepple T, Hallett M. (1999). Feedforward ankle strategy of balance during quiet stance in adults. The Journal of physiology. 514 ( Pt 3) [PubMed]

Gawthrop P, Loram I, Lakie M, Gollee H. (2011). Intermittent control: a computational theory of human control. Biological cybernetics. 104 [PubMed]

Horak FB, Macpherson JM. (2013). Posture Principles of neural science.

Hunter IW, Kearney RE. (1982). Dynamics of human ankle stiffness: variation with mean ankle torque. Journal of biomechanics. 15 [PubMed]

Héroux ME, Dakin CJ, Luu BL, Inglis JT, Blouin JS. (2014). Absence of lateral gastrocnemius activity and differential motor unit behavior in soleus and medial gastrocnemius during standing balance. Journal of applied physiology (Bethesda, Md. : 1985). 116 [PubMed]

Jacobs JV, Horak FB. (2007). Cortical control of postural responses. Journal of neural transmission (Vienna, Austria : 1996). 114 [PubMed]

Johnson MA, Polgar J, Weightman D, Appleton D. (1973). Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. Journal of the neurological sciences. 18 [PubMed]

Kavounoudias A, Roll R, Roll JP. (2001). Foot sole and ankle muscle inputs contribute jointly to human erect posture regulation. The Journal of physiology. 532 [PubMed]

Kearney RE, Hunter IW. (1982). Dynamics of human ankle stiffness: variation with displacement amplitude. Journal of biomechanics. 15 [PubMed]

Kohn AF. (2005). Cross-correlation between EMG and center of gravity during quiet stance: theory and simulations. Biological cybernetics. 93 [PubMed]

Kohn AF, Elias LA. (2013). Individual and collective properties of computationally efficient motoneuron models of types S and F with active dendrites Neurocomputing. 99

Kohn AF, Elias LA, Watanabe RN. (2013). Large-scale neuromusculoskeletal model used to investigate neurophysiological mechanisms behind upright stance control 43rd Annual Meeting of the Society for Neuroscience 293.07.

Kohn AF, Elias LA, Watanabe RN. (2013). Low-frequency fluctuations of plantar flexion torque in force and position control tasks studied experimentally and by a neuromusculoskeletal model 6th International IEEE-EMBS Conference on Neural Engineering (NER).

Kohn AF, Elias LA, Watanabe RN. (2014). The role of reciprocal inhibition on human postural control Proceedings of the Bernstein Conference Gottingen: BFNT-BCCN.

Kohn AF, Elias LA, Watanabe RN, Chaud VM. (2012). A simulation study of the effects of activation-dependent muscle stiffness on proprioceptive feedback and short-latency reflex 4th IEEE RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics..

Kuo AD. (2005). An optimal state estimation model of sensory integration in human postural balance. Journal of neural engineering. 2 [PubMed]

Lawrence EL, Fassola I, Werner I, Leclercq C, Valero-Cuevas FJ. (2014). Quantification of dexterity as the dynamical regulation of instabilities: comparisons across gender, age, and disease. Frontiers in neurology. 5 [PubMed]

Lin CC, Crago PE. (2002). Neural and mechanical contributions to the stretch reflex: a model synthesis. Annals of biomedical engineering. 30 [PubMed]

Loeb GE, Brown IE, Cheng EJ. (1999). A hierarchical foundation for models of sensorimotor control. Experimental brain research. 126 [PubMed]

Loram ID, Gollee H, Lakie M, Gawthrop PJ. (2011). Human control of an inverted pendulum: is continuous control necessary? Is intermittent control effective? Is intermittent control physiological? The Journal of physiology. 589 [PubMed]

Loram ID, Maganaris CN, Lakie M. (2005). Active, non-spring-like muscle movements in human postural sway: how might paradoxical changes in muscle length be produced? The Journal of physiology. 564 [PubMed]

Loram ID, Maganaris CN, Lakie M. (2007). The passive, human calf muscles in relation to standing: the non-linear decrease from short range to long range stiffness. The Journal of physiology. 584 [PubMed]

Loram ID, van de Kamp C, Lakie M, Gollee H, Gawthrop PJ. (2014). Does the motor system need intermittent control? Exercise and sport sciences reviews. 42 [PubMed]

Markram H. (2006). The blue brain project. Nature reviews. Neuroscience. 7 [PubMed]

Masani K, Popovic MR, Nakazawa K, Kouzaki M, Nozaki D. (2003). Importance of body sway velocity information in controlling ankle extensor activities during quiet stance. Journal of neurophysiology. 90 [PubMed]

Masani K, Vette AH, Popovic MR. (2006). Controlling balance during quiet standing: proportional and derivative controller generates preceding motor command to body sway position observed in experiments. Gait & posture. 23 [PubMed]

Matthews PB, Stein RB. (1969). The regularity of primary and secondary muscle spindle afferent discharges. The Journal of physiology. 202 [PubMed]

Maurer C, Peterka RJ. (2005). A new interpretation of spontaneous sway measures based on a simple model of human postural control. Journal of neurophysiology. 93 [PubMed]

McComas AJ. (1991). Invited review: motor unit estimation: methods, results, and present status. Muscle & nerve. 14 [PubMed]

Mello EM, Magalhães FH, Kohn AF. (2013). Larger plantar flexion torque variability implies less stable balance in the young: an association affected by knee position. Human movement science. 32 [PubMed]

Menegaldo LL, de Toledo Fleury A, Weber HI. (2004). Moment arms and musculotendon lengths estimation for a three-dimensional lower-limb model. Journal of biomechanics. 37 [PubMed]

Meyer PF, Oddsson LI, De Luca CJ. (2004). The role of plantar cutaneous sensation in unperturbed stance. Experimental brain research. 156 [PubMed]

Mezzarane RA, Kohn AF. (2007). Control of upright stance over inclined surfaces. Experimental brain research. 180 [PubMed]

Mileusnic MP, Brown IE, Lan N, Loeb GE. (2006). Mathematical models of proprioceptors. I. Control and transduction in the muscle spindle. Journal of neurophysiology. 96 [PubMed]

Morasso PG, Schieppati M. (1999). Can muscle stiffness alone stabilize upright standing? Journal of neurophysiology. 82 [PubMed]

Murnaghan CD, Squair JW, Chua R, Inglis JT, Carpenter MG. (2014). Cortical contributions to control of posture during unrestricted and restricted stance. Journal of neurophysiology. 111 [PubMed]

Nardone A, Schieppati M. (1998). Medium-latency response to muscle stretch in human lower limb: estimation of conduction velocity of group II fibres and central delay. Neuroscience letters. 249 [PubMed]

Nomura T, Oshikawa S, Suzuki Y, Kiyono K, Morasso P. (2013). Modeling human postural sway using an intermittent control and hemodynamic perturbations. Mathematical biosciences. 245 [PubMed]

Peterka RJ. (2000). Postural control model interpretation of stabilogram diffusion analysis. Biological cybernetics. 82 [PubMed]

Prieto TE, Myklebust JB, Hoffmann RG, Lovett EG, Myklebust BM. (1996). Measures of postural steadiness: differences between healthy young and elderly adults. IEEE transactions on bio-medical engineering. 43 [PubMed]

Prochazka A, Hulliger M, Zangger P, Appenteng K. (1985). 'Fusimotor set': new evidence for alpha-independent control of gamma-motoneurones during movement in the awake cat. Brain research. 339 [PubMed]

Proske U, Gandevia SC. (2012). The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiological reviews. 92 [PubMed]

Proske U, Wise AK, Gregory JE. (2000). The role of muscle receptors in the detection of movements. Progress in neurobiology. 60 [PubMed]

Raphael G, Tsianos GA, Loeb GE. (2010). Spinal-like regulator facilitates control of a two-degree-of-freedom wrist. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Sartori M, Reggiani M, Farina D, Lloyd DG. (2012). EMG-driven forward-dynamic estimation of muscle force and joint moment about multiple degrees of freedom in the human lower extremity. PloS one. 7 [PubMed]

Schuurmans J, van der Helm FC, Schouten AC. (2011). Relating reflex gain modulation in posture control to underlying neural network properties using a neuromusculoskeletal model. Journal of computational neuroscience. 30 [PubMed]

Scott SH, Loeb GE. (1994). The computation of position sense from spindles in mono- and multiarticular muscles. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 [PubMed]

Sejnowski TJ, Destexhe A, Mainen Z. (1994). An efficient method for computing synaptic conductances based on a kinetic model of receptor binding Neural Comput. 6

Simoneau GG, Ulbrecht JS, Derr JA, Cavanagh PR. (1995). Role of somatosensory input in the control of human posture. Gait Posture. 3

Stienen AH, Schouten AC, Schuurmans J, van der Helm FC. (2007). Analysis of reflex modulation with a biologically realistic neural network. Journal of computational neuroscience. 23 [PubMed]

Suzuki Y, Nomura T, Casadio M, Morasso P. (2012). Intermittent control with ankle, hip, and mixed strategies during quiet standing: a theoretical proposal based on a double inverted pendulum model. Journal of theoretical biology. 310 [PubMed]

Taube W et al. (2007). Cortical and spinal adaptations induced by balance training: correlation between stance stability and corticospinal activation. Acta physiologica (Oxford, England). 189 [PubMed]

Thelen DG. (2003). Adjustment of muscle mechanics model parameters to simulate dynamic contractions in older adults. Journal of biomechanical engineering. 125 [PubMed]

Ushiyama J, Takahashi Y, Ushiba J. (2010). Muscle dependency of corticomuscular coherence in upper and lower limb muscles and training-related alterations in ballet dancers and weightlifters. Journal of applied physiology (Bethesda, Md. : 1985). 109 [PubMed]

Vieira TM, Loram ID, Muceli S, Merletti R, Farina D. (2012). Recruitment of motor units in the medial gastrocnemius muscle during human quiet standing: is recruitment intermittent? What triggers recruitment? Journal of neurophysiology. 107 [PubMed]

Watanabe RN et al. (2013). Influences of premotoneuronal command statistics on the scaling of motor output variability during isometric plantar flexion. Journal of neurophysiology. 110 [PubMed]

Windhorst U. (2007). Muscle proprioceptive feedback and spinal networks. Brain research bulletin. 73 [PubMed]

Zehr EP. (2002). Considerations for use of the Hoffmann reflex in exercise studies. European journal of applied physiology. 86 [PubMed]

de Vlugt E, de Groot JH, Wisman WH, Meskers CG. (2012). Clonus is explained from increased reflex gain and enlarged tissue viscoelasticity. Journal of biomechanics. 45 [PubMed]

van Soest AJ, Rozendaal LA. (2008). The inverted pendulum model of bipedal standing cannot be stabilized through direct feedback of force and contractile element length and velocity at realistic series elastic element stiffness. Biological cybernetics. 99 [PubMed]

van de Kamp C, Gawthrop PJ, Gollee H, Lakie M, Loram ID. (2013). Interfacing sensory input with motor output: does the control architecture converge to a serial process along a single channel? Frontiers in computational neuroscience. 7 [PubMed]

van de Kamp C, Gawthrop PJ, Gollee H, Loram ID. (2013). Refractoriness in sustained visuo-manual control: is the refractory duration intrinsic or does it depend on external system properties? PLoS computational biology. 9 [PubMed]

van der Kooij H, Jacobs R, Koopman B, Grootenboer H. (1999). A multisensory integration model of human stance control. Biological cybernetics. 80 [PubMed]

van der Kooij H, Jacobs R, Koopman B, van der Helm F. (2001). An adaptive model of sensory integration in a dynamic environment applied to human stance control. Biological cybernetics. 84 [PubMed]

van der Kooij H, de Vlugt E. (2007). Postural responses evoked by platform pertubations are dominated by continuous feedback. Journal of neurophysiology. 98 [PubMed]

References and models that cite this paper

Allen JM, Elbasiouny SM. (2018). The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors. Journal of neural engineering. 15 [PubMed]

Kim H. (2017). Impact of the localization of dendritic calcium persistent inward current on the input-output properties of spinal motoneuron pool: a computational study. Journal of applied physiology (Bethesda, Md. : 1985). 123 [PubMed]

Vannucci L, Falotico E, Laschi C. (2017). Proprioceptive Feedback through a Neuromorphic Muscle Spindle Model. Frontiers in neuroscience. 11 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.