Layer 5 Pyramidal Neuron (Shai et al., 2015)

This work contains a NEURON model for a layer 5 pyramidal neuron (based on Hay et al., 2011) with distributed groups of synapses across the basal and tuft dendrites. The results of that simulation are used to fit a phenomenological model, which is also included in this file.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Neocortex L5/6 pyramidal GLU cell

Transmitters: Glutamate

Model Concept(s): Dendritic Action Potentials; Active Dendrites

Simulation Environment: NEURON; MATLAB


Shai AS, Anastassiou CA, Larkum ME, Koch C. (2015). Physiology of layer 5 pyramidal neurons in mouse primary visual cortex: coincidence detection through bursting. PLoS computational biology. 11 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.