Accorsi-Mendonça D, Machado BH. (2013). Synaptic transmission of baro- and chemoreceptors afferents in the NTS second order neurons. Autonomic neuroscience : basic & clinical. 175 [PubMed]
Anirudhan A, Narayanan R. (2015). Analogous synaptic plasticity profiles emerge from disparate channel combinations. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35 [PubMed]
Azar T, Sharp J, Lawson D. (2011). Heart rates of male and female Sprague-Dawley and spontaneously hypertensive rats housed singly or in groups. Journal of the American Association for Laboratory Animal Science : JAALAS. 50 [PubMed]
Bhalla US, Bower JM. (1993). Exploring parameter space in detailed single neuron models: simulations of the mitral and granule cells of the olfactory bulb. Journal of neurophysiology. 69 [PubMed]
Bhalla US, Iyengar R. (1999). Emergent properties of networks of biological signaling pathways. Science (New York, N.Y.). 283 [PubMed]
Cannon RC, D'Alessandro G. (2006). The ion channel inverse problem: neuroinformatics meets biophysics. PLoS computational biology. 2 [PubMed]
Cuadra AE, Shan Z, Sumners C, Raizada MK. (2010). A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? Pharmacology & therapeutics. 125 [PubMed]
Cunningham JP, Yu BM. (2014). Dimensionality reduction for large-scale neural recordings. Nature neuroscience. 17 [PubMed]
Dalla Torre di Sanguinetto SA, Dasen JS, Arber S. (2008). Transcriptional mechanisms controlling motor neuron diversity and connectivity. Current opinion in neurobiology. 18 [PubMed]
Dampney RA, Tan PS, Sheriff MJ, Fontes MA, Horiuchi J. (2007). Cardiovascular effects of angiotensin II in the rostral ventrolateral medulla: the push-pull hypothesis. Current hypertension reports. 9 [PubMed]
Dayan P. (2012). Twenty-five lessons from computational neuromodulation. Neuron. 76 [PubMed]
Dean CB, Nielsen JD. (2007). Generalized linear mixed models: a review and some extensions. Lifetime data analysis. 13 [PubMed]
Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ. (2001). Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons. Neuroscience. 107 [PubMed]
Donoghue S, Garcia M, Jordan D, Spyer KM. (1982). Identification and brain-stem projections of aortic baroreceptor afferent neurones in nodose ganglia of cats and rabbits. The Journal of physiology. 322 [PubMed]
Edelman GM, Gally JA. (2001). Degeneracy and complexity in biological systems. Proceedings of the National Academy of Sciences of the United States of America. 98 [PubMed]
Eriksson L, Wold S, Sjstrm M. (2001). PLS-Regression: a Basic Tool of Chemometrics Chemometrics and Intelligent Laboratory Systems. 58(2)
Ferguson AV, Washburn DL, Latchford KJ. (2001). Hormonal and neurotransmitter roles for angiotensin in the regulation of central autonomic function. Experimental biology and medicine (Maywood, N.J.). 226 [PubMed]
Finkel LH. (2000). Neuroengineering models of brain disease. Annual review of biomedical engineering. 2 [PubMed]
Foster WR, Ungar LH, Schwaber JS. (1993). Significance of conductances in Hodgkin-Huxley models. Journal of neurophysiology. 70 [PubMed]
Gelband CH et al. (1999). Angiotensin II type 1 receptor-mediated inhibition of K+ channel subunit kv2.2 in brain stem and hypothalamic neurons. Circulation research. 84 [PubMed]
Grashow R, Brookings T, Marder E. (2009). Reliable neuromodulation from circuits with variable underlying structure. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]
Guan D, Armstrong WE, Foehring RC. (2013). Kv2 channels regulate firing rate in pyramidal neurons from rat sensorimotor cortex. The Journal of physiology. 591 [PubMed]
Guenther E, Schmid S, Hewig B, Kohler K. (1996). Two-fold effect of Angiotensin II on voltage-dependent calcium currents in rat retinal ganglion cells. Brain research. 718 [PubMed]
Guyenet PG. (2006). The sympathetic control of blood pressure. Nature reviews. Neuroscience. 7 [PubMed]
HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]
Hadzipasic M et al. (2014). Selective degeneration of a physiological subtype of spinal motor neuron in mice with SOD1-linked ALS. Proceedings of the National Academy of Sciences of the United States of America. 111 [PubMed]
Hagiwara K, Nunoki K, Ishii K, Abe T, Yanagisawa T. (2003). Differential inhibition of transient outward currents of Kv1.4 and Kv4.3 by endothelin. Biochemical and biophysical research communications. 310 [PubMed]
Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM. (2004). ModelDB: A Database to Support Computational Neuroscience. Journal of computational neuroscience. 17 [PubMed]
Hogarty DC, Speakman EA, Puig V, Phillips MI. (1992). The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking and vasopressin responses to central angiotensin. Brain research. 586 [PubMed]
Hudson AE, Prinz AA. (2010). Conductance ratios and cellular identity. PLoS computational biology. 6 [PubMed]
Hübner CA, Jentsch TJ. (2002). Ion channel diseases. Human molecular genetics. 11 [PubMed]
Janes KA, Yaffe MB. (2006). Data-driven modelling of signal-transduction networks. Nature reviews. Molecular cell biology. 7 [PubMed]
Jensen KJ, Janes KA. (2012). Modeling the latent dimensions of multivariate signaling datasets. Physical biology. 9 [PubMed]
Joshi SH, Klassen E, Srivastava A, Jermyn I. (2007). A Novel Representation for Riemannian Analysis of Elastic Curves in R Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. 2007 [PubMed]
Kaczorowski GJ, McManus OB, Priest BT, Garcia ML. (2008). Ion channels as drug targets: the next GPCRs. The Journal of general physiology. 131 [PubMed]
Kingsford C, Salzberg SL. (2008). What are decision trees? Nature biotechnology. 26 [PubMed]
Kispersky TJ, Caplan JS, Marder E. (2012). Increase in sodium conductance decreases firing rate and gain in model neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]
Klassen T et al. (2011). Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy. Cell. 145 [PubMed]
Koch C. (1998). Biophysics of Computation: Information Processing in Single Neurons.
Kotaleski JH, Blackwell KT. (2010). Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Nature reviews. Neuroscience. 11 [PubMed]
Kuhn M. (2008). Building predictive models in R using the caret package Journal of Statistical Software. 28(5)
Köndgen H et al. (2008). The dynamical response properties of neocortical neurons to temporally modulated noisy inputs in vitro. Cerebral cortex (New York, N.Y. : 1991). 18 [PubMed]
LeMasson G, Marder E, Abbott LF. (1993). Activity-dependent regulation of conductances in model neurons. Science (New York, N.Y.). 259 [PubMed]
Levitan IB. (1994). Modulation of ion channels by protein phosphorylation and dephosphorylation. Annual review of physiology. 56 [PubMed]
Li L. (2010). Dimension reduction for high-dimensional data. Methods in molecular biology (Clifton, N.J.). 620 [PubMed]
Liaw A, Wiener M. (2002). Classification and regression by randomForest R news. 2(3)
Lipski J, McAllen RM, Spyer KM. (1975). The sinus nerve and baroreceptor input to the medulla of the cat. The Journal of physiology. 251 [PubMed]
Liu PW, Bean BP. (2014). Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]
Makadia HK et al. (2015). Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology. Biophysical journal. 108 [PubMed]
Marder E. (2011). Variability, compensation, and modulation in neurons and circuits. Proceedings of the National Academy of Sciences of the United States of America. 108 Suppl 3 [PubMed]
Marder E. (2012). Neuromodulation of neuronal circuits: back to the future. Neuron. 76 [PubMed]
Marder E, O'Leary T, Shruti S. (2014). Neuromodulation of circuits with variable parameters: single neurons and small circuits reveal principles of state-dependent and robust neuromodulation. Annual review of neuroscience. 37 [PubMed]
Marder E, Taylor AL. (2011). Multiple models to capture the variability in biological neurons and networks. Nature neuroscience. 14 [PubMed]
McCubbin JW, DeMoura RS, Page IH, Olmsted F. (1965). Arterial hypertension elicited by subpressor amounts of angiotensin. Science (New York, N.Y.). 149 [PubMed]
McGarry LM et al. (2010). Quantitative classification of somatostatin-positive neocortical interneurons identifies three interneuron subtypes. Frontiers in neural circuits. 4 [PubMed]
Mevik BH, Wehrens R. (2007). The pls package: Principal component and partial least squares regression in R Journal of Statistical Software. 18(2)
Mifflin SW, Spyer KM, Withington-Wray DJ. (1988). Baroreceptor inputs to the nucleus tractus solitarius in the cat: postsynaptic actions and the influence of respiration. The Journal of physiology. 399 [PubMed]
Mishra J, Bhalla US. (2002). Simulations of inositol phosphate metabolism and its interaction with InsP(3)-mediated calcium release. Biophysical journal. 83 [PubMed]
Misonou H et al. (2004). Regulation of ion channel localization and phosphorylation by neuronal activity. Nature neuroscience. 7 [PubMed]
Mitra AK, Gao L, Zucker IH. (2010). Angiotensin II-induced upregulation of AT(1) receptor expression: sequential activation of NF-kappaB and Elk-1 in neurons. American journal of physiology. Cell physiology. 299 [PubMed]
Moresco EM, Li X, Beutler B. (2013). Going forward with genetics: recent technological advances and forward genetics in mice. The American journal of pathology. 182 [PubMed]
Nadim F, Bucher D. (2014). Neuromodulation of neurons and synapses. Current opinion in neurobiology. 29 [PubMed]
O'Leary T, Williams AH, Caplan JS, Marder E. (2013). Correlations in ion channel expression emerge from homeostatic tuning rules. Proceedings of the National Academy of Sciences of the United States of America. 110 [PubMed]
O'Leary T, Williams AH, Franci A, Marder E. (2014). Cell types, network homeostasis, and pathological compensation from a biologically plausible ion channel expression model. Neuron. 82 [PubMed]
O'Leary T, Wyllie DJ. (2011). Neuronal homeostasis: time for a change? The Journal of physiology. 589 [PubMed]
Ogunnaike BA. (2009). Random Phenomena: Fundamentals of Probability.
Park J et al. (2014). Inputs drive cell phenotype variability. Genome research. 24 [PubMed]
Paton JF, Kasparov S. (1999). Differential effects of angiotensin II on cardiorespiratory reflexes mediated by nucleus tractus solitarii - a microinjection study in the rat. The Journal of physiology. 521 Pt 1 [PubMed]
Paton JF, Wang S, Polson JW, Kasparov S. (2008). Signalling across the blood brain barrier by angiotensin II: novel implications for neurogenic hypertension. Journal of molecular medicine (Berlin, Germany). 86 [PubMed]
Penela P et al. (2006). Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovascular research. 69 [PubMed]
Phillips MI, Sumners C. (1998). Angiotensin II in central nervous system physiology. Regulatory peptides. 78 [PubMed]
Prescott SA, De Koninck Y, Sejnowski TJ. (2008). Biophysical basis for three distinct dynamical mechanisms of action potential initiation. PLoS computational biology. 4 [PubMed]
Qi Y. (2012). Ensemble machine learning.
Ramocki MB, Zoghbi HY. (2008). Failure of neuronal homeostasis results in common neuropsychiatric phenotypes. Nature. 455 [PubMed]
Rathour RK, Narayanan R. (2012). Inactivating ion channels augment robustness of subthreshold intrinsic response dynamics to parametric variability in hippocampal model neurons. The Journal of physiology. 590 [PubMed]
Rathour RK, Narayanan R. (2014). Homeostasis of functional maps in active dendrites emerges in the absence of individual channelostasis. Proceedings of the National Academy of Sciences of the United States of America. 111 [PubMed]
Ritter SL, Hall RA. (2009). Fine-tuning of GPCR activity by receptor-interacting proteins. Nature reviews. Molecular cell biology. 10 [PubMed]
Roden DM. (2008). Repolarization reserve: a moving target. Circulation. 118 [PubMed]
Rogers RF, Rybak IA, Schwaber JS. (2000). Computational modeling of the baroreflex arc: nucleus tractus solitarius. Brain research bulletin. 51 [PubMed]
Rybak IA, Paton JF, Schwaber JS. (1997). Modeling neural mechanisms for genesis of respiratory rhythm and pattern. I. Models of respiratory neurons. Journal of neurophysiology. 77 [PubMed]
Sarkar AX, Christini DJ, Sobie EA. (2012). Exploiting mathematical models to illuminate electrophysiological variability between individuals. The Journal of physiology. 590 [PubMed]
Schulz DJ, Goaillard JM, Marder E. (2006). Variable channel expression in identified single and electrically coupled neurons in different animals. Nature neuroscience. 9 [PubMed]
Schulz DJ, Goaillard JM, Marder EE. (2007). Quantitative expression profiling of identified neurons reveals cell-specific constraints on highly variable levels of gene expression. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]
Shan Z et al. (2013). Chronic knockdown of the nucleus of the solitary tract AT1 receptors increases blood inflammatory-endothelial progenitor cell ratio and exacerbates hypertension in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979). 61 [PubMed]
Smyth JW, Shaw RM. (2010). Forward trafficking of ion channels: what the clinician needs to know. Heart rhythm. 7 [PubMed]
Spaethling JM et al. (2014). Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28 [PubMed]
Sumners C, Fleegal MA, Zhu M. (2002). Angiotensin AT1 receptor signalling pathways in neurons. Clinical and experimental pharmacology & physiology. 29 [PubMed]
Sun K, Marchand-Maillet S. (2014). An Information Geometry of Statistical Manifold Learning Proceedings of the 31 st International Conference on Machine Learning. Beijing, China. 14
Sévoz-Couche C, Spyer KM, Jordan D. (2000). In vivo modulation of vagal-identified dorsal medullary neurones by activation of different 5-Hydroxytryptamine(2) receptors in rats. British journal of pharmacology. 131 [PubMed]
Taylor AL, Goaillard JM, Marder E. (2009). How multiple conductances determine electrophysiological properties in a multicompartment model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]
Taylor AL, Hickey TJ, Prinz AA, Marder E. (2006). Structure and visualization of high-dimensional conductance spaces. Journal of neurophysiology. 96 [PubMed]
Temporal S, Lett KM, Schulz DJ. (2014). Activity-dependent feedback regulates correlated ion channel mRNA levels in single identified motor neurons. Current biology : CB. 24 [PubMed]
Tobin AE, Cruz-Bermúdez ND, Marder E, Schulz DJ. (2009). Correlations in ion channel mRNA in rhythmically active neurons. PloS one. 4 [PubMed]
Toledo-Rodriguez M et al. (2004). Correlation maps allow neuronal electrical properties to be predicted from single-cell gene expression profiles in rat neocortex. Cerebral cortex (New York, N.Y. : 1991). 14 [PubMed]
Torben-Nielsen B, Stiefel KM. (2009). Systematic mapping between dendritic function and structure. Network (Bristol, England). 20 [PubMed]
Torben-Nielsen B, Stiefel KM. (2010). Wide-field motion integration in fly VS cells: insights from an inverse approach. PLoS computational biology. 6 [PubMed]
Tripathy SJ, Burton SD, Geramita M, Gerkin RC, Urban NN. (2015). Brain-wide analysis of electrophysiological diversity yields novel categorization of mammalian neuron types. Journal of neurophysiology. 113 [PubMed]
Vadigepalli R, Doyle FJ, Schwaber JS. (2001). Analysis and neuronal modeling of the nonlinear characteristics of a local cardiac reflex in the rat. Neural computation. 13 [PubMed]
Wang D, Gelband CH, Sumners C, Posner P. (1997). Mechanisms underlying the chronotropic effect of angiotensin II on cultured neurons from rat hypothalamus and brain stem. Journal of neurophysiology. 78 [PubMed]
Wolfram V et al. (2014). The transcription factors islet and Lim3 combinatorially regulate ion channel gene expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]
Zhang C, Song Y, Xiang S, Nie F. (2008). A unified framework for semi-supervised dimensionality reduction Pattern Recognition. 41(9)