Excitability of DA neurons and their regulation by synaptic input (Morozova et al. 2016a, 2016b)


Morozova EO et al. (2016). Contribution of synchronized GABAergic neurons to dopaminergic neuron firing and bursting. Journal of neurophysiology. 116 [PubMed]

See more from authors: Morozova EO · Myroshnychenko M · Zakharov D · di Volo M · Gutkin B · Lapish CC · Kuznetsov A

References and models cited by this paper

Adhikari MH, Quilichini PP, Roy D, Jirsa V, Bernard C. (2012). Brain state dependent postinhibitory rebound in entorhinal cortex interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

Alger BE, Nicoll RA. (1979). GABA-mediated biphasic inhibitory responses in hippocampus. Nature. 281 [PubMed]

Amarasingham A, Harrison MT, Hatsopoulos NG, Geman S. (2012). Conditional modeling and the jitter method of spike resampling. Journal of neurophysiology. 107 [PubMed]

Andersen P, Dingledine R, Gjerstad L, Langmoen IA, Laursen AM. (1980). Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid. The Journal of physiology. 305 [PubMed]

Berretta N, Paolucci E, Bernardi G, Mercuri NB. (2001). Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons. The European journal of neuroscience. 14 [PubMed]

Blythe SN, Wokosin D, Atherton JF, Bevan MD. (2009). Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Bocklisch C et al. (2013). Cocaine disinhibits dopamine neurons by potentiation of GABA transmission in the ventral tegmental area. Science (New York, N.Y.). 341 [PubMed]

Bourdy R, Barrot M. (2012). A new control center for dopaminergic systems: pulling the VTA by the tail. Trends in neurosciences. 35 [PubMed]

Brinschwitz K et al. (2010). Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain. Neuroscience. 168 [PubMed]

Bromberg-Martin ES, Matsumoto M, Hikosaka O. (2010). Dopamine in motivational control: rewarding, aversive, and alerting. Neuron. 68 [PubMed]

Canavier CC, Landry RS. (2006). An increase in AMPA and a decrease in SK conductance increase burst firing by different mechanisms in a model of a dopamine neuron in vivo. Journal of neurophysiology. 96 [PubMed]

Carter BC, Giessel AJ, Sabatini BL, Bean BP. (2012). Transient sodium current at subthreshold voltages: activation by EPSP waveforms. Neuron. 75 [PubMed]

Celada P, Paladini CA, Tepper JM. (1999). GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata. Neuroscience. 89 [PubMed]

Chergui K et al. (1993). Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo. The European journal of neuroscience. 5 [PubMed]

Christie MJ, Bridge S, James LB, Beart PM. (1985). Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area. Brain research. 333 [PubMed]

Cobb SR, Buhl EH, Halasy K, Paulsen O, Somogyi P. (1995). Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature. 378 [PubMed]

Cohen JY, Haesler S, Vong L, Lowell BB, Uchida N. (2012). Neuron-type-specific signals for reward and punishment in the ventral tegmental area. Nature. 482 [PubMed]

Deister CA, Teagarden MA, Wilson CJ, Paladini CA. (2009). An intrinsic neuronal oscillator underlies dopaminergic neuron bursting. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Destexhe A, Mainen ZF, Sejnowski TJ. (1994). Synthesis of models for excitable membranes, synaptic transmission and neuromodulation using a common kinetic formalism. Journal of computational neuroscience. 1 [PubMed]

Diba K, Amarasingham A, Mizuseki K, Buzsáki G. (2014). Millisecond timescale synchrony among hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Dobi A, Margolis EB, Wang HL, Harvey BK, Morales M. (2010). Glutamatergic and nonglutamatergic neurons of the ventral tegmental area establish local synaptic contacts with dopaminergic and nondopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Durante P, Cardenas CG, Whittaker JA, Kitai ST, Scroggs RS. (2004). Low-threshold L-type calcium channels in rat dopamine neurons. Journal of neurophysiology. 91 [PubMed]

Eshel N et al. (2015). Arithmetic and local circuitry underlying dopamine prediction errors. Nature. 525 [PubMed]

Floresco SB, West AR, Ash B, Moore H, Grace AA. (2003). Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nature neuroscience. 6 [PubMed]

Fujisawa S, Amarasingham A, Harrison MT, Buzsáki G. (2008). Behavior-dependent short-term assembly dynamics in the medial prefrontal cortex. Nature neuroscience. 11 [PubMed]

Garris PA, Wightman RM. (1994). Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex, and striatum: an in vivo voltammetric study. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 [PubMed]

Grace AA. (1991). Regulation of spontaneous activity and oscillatory spike firing in rat midbrain dopamine neurons recorded in vitro. Synapse (New York, N.Y.). 7 [PubMed]

Grace AA, Bunney BS. (1979). Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. European journal of pharmacology. 59 [PubMed]

Grace AA, Bunney BS. (1984). The control of firing pattern in nigral dopamine neurons: burst firing. The Journal of neuroscience : the official journal of the Society for Neuroscience. 4 [PubMed]

Grace AA, Bunney BS. (1984). The control of firing pattern in nigral dopamine neurons: single spike firing. The Journal of neuroscience : the official journal of the Society for Neuroscience. 4 [PubMed]

Grace AA, Bunney BS, Moore H, Todd CL. (1997). Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends in neurosciences. 20 [PubMed]

Grace AA, Floresco SB, Goto Y, Lodge DJ. (2007). Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends in neurosciences. 30 [PubMed]

Grace AA, Onn SP. (1989). Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. 9 [PubMed]

Graupner M, Gutkin B. (2009). Modeling nicotinic neuromodulation from global functional and network levels to nAChR based mechanisms. Acta pharmacologica Sinica. 30 [PubMed]

Grenhoff J, Aston-Jones G, Svensson TH. (1986). Nicotinic effects on the firing pattern of midbrain dopamine neurons. Acta physiologica Scandinavica. 128 [PubMed]

Gulledge AT, Stuart GJ. (2003). Excitatory actions of GABA in the cortex. Neuron. 37 [PubMed]

Ha J, Kuznetsov A. (2013). Interaction of NMDA receptor and pacemaking mechanisms in the midbrain dopaminergic neuron. PloS one. 8 [PubMed]

Helton TD, Xu W, Lipscombe D. (2005). Neuronal L-type calcium channels open quickly and are inhibited slowly. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Henny P et al. (2012). Structural correlates of heterogeneous in vivo activity of midbrain dopaminergic neurons. Nature neuroscience. 15 [PubMed]

Henry DJ, Wise RA, Rompré PP, White FJ. (1992). Acute depolarization block of A10 dopamine neurons: interactions of morphine with dopamine antagonists. Brain research. 596 [PubMed]

Hikosaka O. (2010). The habenula: from stress evasion to value-based decision-making. Nature reviews. Neuroscience. 11 [PubMed]

Hille B. (1996). A K+ channel worthy of attention. Science (New York, N.Y.). 273 [PubMed]

Hollerman JR, Schultz W. (1998). Dopamine neurons report an error in the temporal prediction of reward during learning. Nature neuroscience. 1 [PubMed]

Hong S, Jhou TC, Smith M, Saleem KS, Hikosaka O. (2011). Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Horvitz JC. (2000). Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events. Neuroscience. 96 [PubMed]

Isaacson JS, Scanziani M. (2011). How inhibition shapes cortical activity. Neuron. 72 [PubMed]

Jhou TC, Fields HL, Baxter MG, Saper CB, Holland PC. (2009). The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron. 61 [PubMed]

Jhou TC, Geisler S, Marinelli M, Degarmo BA, Zahm DS. (2009). The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. The Journal of comparative neurology. 513 [PubMed]

Johnson SW, North RA. (1992). Two types of neurone in the rat ventral tegmental area and their synaptic inputs. The Journal of physiology. 450 [PubMed]

Johnson SW, North RA. (1992). Opioids excite dopamine neurons by hyperpolarization of local interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 12 [PubMed]

Johnson SW, Seutin V, North RA. (1992). Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science (New York, N.Y.). 258 [PubMed]

Johnson SW, Wu YN. (2004). Multiple mechanisms underlie burst firing in rat midbrain dopamine neurons in vitro. Brain research. 1019 [PubMed]

Kaufling J, Veinante P, Pawlowski SA, Freund-Mercier MJ, Barrot M. (2009). Afferents to the GABAergic tail of the ventral tegmental area in the rat. The Journal of comparative neurology. 513 [PubMed]

Kitai ST, Shepard PD, Callaway JC, Scroggs R. (1999). Afferent modulation of dopamine neuron firing patterns. Current opinion in neurobiology. 9 [PubMed]

Komendantov AO, Komendantova OG, Johnson SW, Canavier CC. (2004). A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons. Journal of neurophysiology. 91 [PubMed]

Kuznetsov AS, Zakharov DG. (2015). On the dynamical mechanisms of influence of synaptic currents on the neuron model with response differentiation JETP Lett. 102

Lammel S et al. (2008). Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron. 57 [PubMed]

Lecca S, Melis M, Luchicchi A, Muntoni AL, Pistis M. (2012). Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 37 [PubMed]

Li YX, Bertram R, Rinzel J. (1996). Modeling N-methyl-D-aspartate-induced bursting in dopamine neurons. Neuroscience. 71 [PubMed]

Lobb CJ, Troyer TW, Wilson CJ, Paladini CA. (2011). Disinhibition bursting of dopaminergic neurons. Frontiers in systems neuroscience. 5 [PubMed]

Lobb CJ, Wilson CJ, Paladini CA. (2010). A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons. Journal of neurophysiology. 104 [PubMed]

Lobb CJ, Wilson CJ, Paladini CA. (2011). High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons. Journal of neurophysiology. 105 [PubMed]

Lodge DJ, Grace AA. (2006). The laterodorsal tegmentum is essential for burst firing of ventral tegmental area dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America. 103 [PubMed]

Margolis EB, Toy B, Himmels P, Morales M, Fields HL. (2012). Identification of rat ventral tegmental area GABAergic neurons. PloS one. 7 [PubMed]

Mittmann W, Koch U, Häusser M. (2005). Feed-forward inhibition shapes the spike output of cerebellar Purkinje cells. The Journal of physiology. 563 [PubMed]

Mundorf ML, Joseph JD, Austin CM, Caron MG, Wightman RM. (2001). Catecholamine release and uptake in the mouse prefrontal cortex. Journal of neurochemistry. 79 [PubMed]

Nair-Roberts RG et al. (2008). Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. 152 [PubMed]

Omelchenko N, Sesack SR. (2009). Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. Synapse (New York, N.Y.). 63 [PubMed]

Oster AM, Gutkin BS. (2011). A reduced model of DA neuronal dynamics that displays quiescence, tonic firing and bursting. Journal of physiology, Paris. 105 [PubMed]

Overton P, Clark D. (1992). Iontophoretically administered drugs acting at the N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat. Synapse (New York, N.Y.). 10 [PubMed]

Overton PG, Clark D. (1997). Burst firing in midbrain dopaminergic neurons. Brain research. Brain research reviews. 25 [PubMed]

Oyama K, Hernádi I, Iijima T, Tsutsui K. (2010). Reward prediction error coding in dorsal striatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Oyama K et al. (2015). Discrete coding of stimulus value, reward expectation, and reward prediction error in the dorsal striatum. Journal of neurophysiology. 114 [PubMed]

Paladini CA, Roeper J. (2014). Generating bursts (and pauses) in the dopamine midbrain neurons. Neuroscience. 282 [PubMed]

Pan WX, Brown J, Dudman JT. (2013). Neural signals of extinction in the inhibitory microcircuit of the ventral midbrain. Nature neuroscience. 16 [PubMed]

Pan WX, Hyland BI. (2005). Pedunculopontine tegmental nucleus controls conditioned responses of midbrain dopamine neurons in behaving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Pennartz CM, Kitai ST. (1991). Hippocampal inputs to identified neurons in an in vitro slice preparation of the rat nucleus accumbens: evidence for feed-forward inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. 11 [PubMed]

Pikovsky A, Zaks M, Rosenblum M, Osipov G, Kurths J. (1997). Phase synchronization of chaotic oscillations in terms of periodic orbits. Chaos (Woodbury, N.Y.). 7 [PubMed]

Pouille F, Scanziani M. (2001). Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition. Science (New York, N.Y.). 293 [PubMed]

Puopolo M, Raviola E, Bean BP. (2007). Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Quiroga RQ, Nadasdy Z, Ben-Shaul Y. (2004). Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering. Neural computation. 16 [PubMed]

Ribak CE, Vaughn JE, Saito K, Barber R, Roberts E. (1976). Immunocytochemical localization of glutamate decarboxylase in rat substantia nigra. Brain research. 116 [PubMed]

Richards CD, Shiroyama T, Kitai ST. (1997). Electrophysiological and immunocytochemical characterization of GABA and dopamine neurons in the substantia nigra of the rat. Neuroscience. 80 [PubMed]

Roeper J. (2013). Dissecting the diversity of midbrain dopamine neurons. Trends in neurosciences. 36 [PubMed]

Rossant C et al. (2016). Spike sorting for large, dense electrode arrays. Nature neuroscience. 19 [PubMed]

Schultz W. (1998). Predictive reward signal of dopamine neurons. Journal of neurophysiology. 80 [PubMed]

Scroggs RS, Cardenas CG, Whittaker JA, Kitai ST. (2001). Muscarine reduces calcium-dependent electrical activity in substantia nigra dopaminergic neurons. Journal of neurophysiology. 86 [PubMed]

Sesack SR, Pickel VM. (1992). Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. The Journal of comparative neurology. 320 [PubMed]

Shepard PD, Bunney BS. (1991). Repetitive firing properties of putative dopamine-containing neurons in vitro: regulation by an apamin-sensitive Ca(2+)-activated K+ conductance. Experimental brain research. 86 [PubMed]

Sohal VS, Zhang F, Yizhar O, Deisseroth K. (2009). Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature. 459 [PubMed]

Steffensen SC, Svingos AL, Pickel VM, Henriksen SJ. (1998). Electrophysiological characterization of GABAergic neurons in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Steffensen SC et al. (2008). Cocaine disinhibits dopamine neurons in the ventral tegmental area via use-dependent blockade of GABA neuron voltage-sensitive sodium channels. The European journal of neuroscience. 28 [PubMed]

Stobbs SH et al. (2004). Ethanol suppression of ventral tegmental area GABA neuron electrical transmission involves N-methyl-D-aspartate receptors. The Journal of pharmacology and experimental therapeutics. 311 [PubMed]

Swadlow HA. (2002). Thalamocortical control of feed-forward inhibition in awake somatosensory 'barrel' cortex. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 357 [PubMed]

Tan KR et al. (2012). GABA neurons of the VTA drive conditioned place aversion. Neuron. 73 [PubMed]

Tateno T, Robinson HP. (2011). The mechanism of ethanol action on midbrain dopaminergic neuron firing: a dynamic-clamp study of the role of I(h) and GABAergic synaptic integration. Journal of neurophysiology. 106 [PubMed]

Tepper JM, Lee CR. (2007). GABAergic control of substantia nigra dopaminergic neurons. Progress in brain research. 160 [PubMed]

Tepper JM, Martin LP, Anderson DR. (1995). GABAA receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 15 [PubMed]

Theile JW, Morikawa H, Gonzales RA, Morrisett RA. (2011). GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons. Neuroscience. 172 [PubMed]

Tolu S et al. (2013). Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement. Molecular psychiatry. 18 [PubMed]

Tong ZY, Overton PG, Clark D. (1996). Antagonism of NMDA receptors but not AMPA/kainate receptors blocks bursting in dopaminergic neurons induced by electrical stimulation of the prefrontal cortex. Journal of neural transmission (Vienna, Austria : 1996). 103 [PubMed]

Wang XJ, Buzsáki G. (1996). Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Waroux O et al. (2005). SK channels control the firing pattern of midbrain dopaminergic neurons in vivo. The European journal of neuroscience. 22 [PubMed]

Watabe-Uchida M, Zhu L, Ogawa SK, Vamanrao A, Uchida N. (2012). Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron. 74 [PubMed]

Wehr M, Zador AM. (2003). Balanced inhibition underlies tuning and sharpens spike timing in auditory cortex. Nature. 426 [PubMed]

Westerink BH, Kwint HF, deVries JB. (1996). The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Wightman RM, Zimmerman JB. (1990). Control of dopamine extracellular concentration in rat striatum by impulse flow and uptake. Brain research. Brain research reviews. 15 [PubMed]

Wilson CJ, Callaway JC. (2000). Coupled oscillator model of the dopaminergic neuron of the substantia nigra. Journal of neurophysiology. 83 [PubMed]

Wilson CL, Puntis M, Lacey MG. (2004). Overwhelmingly asynchronous firing of rat subthalamic nucleus neurones in brain slices provides little evidence for intrinsic interconnectivity. Neuroscience. 123 [PubMed]

Woodruff AR, Monyer H, Sah P. (2006). GABAergic excitation in the basolateral amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Xia Y et al. (2011). Nucleus accumbens medium spiny neurons target non-dopaminergic neurons in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Zweifel LS et al. (2009). Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

van Zessen R, Phillips JL, Budygin EA, Stuber GD. (2012). Activation of VTA GABA neurons disrupts reward consumption. Neuron. 73 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.