Minimal model of the VTA (ventral segmental area) representing two (GABA versus dopamine) neuron populations and two subtypes of nicotinic receptors (alpha4beta2 versus alpha7). The model is used to tell apart circuit from receptor mechanisms in the nicotinic control of dopamine release and its pharmacological manipulation.
Region(s) or Organism(s): Basal ganglia
Cell Type(s): Ventral tegmental area dopamine neuron
Simulation Environment: XPPAUT
Implementer(s): Maex, Reinoud [reinoud at bbf.uia.ac.be]