This archive instantiates the single-cell cortical models used in (Aberra et al. 2018) and sets up extracellular stimulation with either a point-current source, to simulate intracortical microstimulation (ICMS), or a uniform E-field distribution, with a monophasic, rectangular pulse waveform in both cases.
Model Type: Neuron or other electrically excitable cell; Axon
Region(s) or Organism(s): Neocortex; Barrel cortex
Cell Type(s): Myelinated neuron
Model Concept(s): Action Potential Initiation; Detailed Neuronal Models
Simulation Environment: NEURON
Implementer(s): Aberra, Aman [aman.aberra at duke.edu]
References:
Aberra AS, Peterchev AV, Grill WM. (2018). Biophysically realistic neuron models for simulation of cortical stimulation. Journal of neural engineering. 15 [PubMed]