In this study we report theta-frequency (3-12 Hz) bursting and resonance in rat cerebellar granule cells and show that these neurons express a previously unidentified slow repolarizing K1 current (IK-slow ). Our experimental and modeling results indicate that IK-slow was necessary for both bursting and resonance. See paper for more.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Cerebellum interneuron granule GLU cell
Simulation Environment: NEURON
Implementer(s): D'Angelo, Egidio [dangelo at unipv.it]
D'Angelo E et al. (2001). Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]