Simulated light response in rod photoreceptors (Liu and Kourennyi 2004)

We developed a complete computer model of the rod, which accurately reproduced the main features of the light response and allowed us to demonstrate that it was suppression of Kx channels that was essential for slowing SLR and increasing excitability of rods. The results reported in this work further establish the importance of Kx channels in rod photoreceptor function.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Retina photoreceptor cone GLU cell

Currents: I Chloride; I L high threshold; I K; I h; I K,Ca; I Potassium

Model Concept(s): Action Potential Initiation; Oscillations; Action Potentials; Calcium dynamics

Simulation Environment: NEURON

Implementer(s): Kourennyi, Dmitri E [dek at]; Liu, Xiaodong [xliu22 at]


Liu XD, Kourennyi DE. (2004). Effects of tetraethylammonium on Kx channels and simulated light response in rod photoreceptors. Annals of biomedical engineering. 32 [PubMed]

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