"LabHEART is an easy to use program that simulates the cardiac action potential, calcium transient and ionic currents. Key parameters such as ionic concentration, stimulus waveform and channel conductance can easily be changed by a click on an icon or dragging a slider. It is a powerfull tool for teaching and researching cardiac electrophysiology."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Heart cell; Cardiac ventricular cell
Model Concept(s): Ion Channel Kinetics; Temporal Pattern Generation; Tutorial/Teaching; Action Potentials; Heart disease
Simulation Environment: MATLAB (web link to model)
Implementer(s): Bers, Donald M; Puglisi, Jose ; Salah, Wajeeh
References:
Puglisi JL, Bers DM. (2001). LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport. American journal of physiology. Cell physiology. 281 [PubMed]
Busjahn A et al. (2004). Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 14 [PubMed]