Model of the 3-cell core CPG (DSI, C2, and VSI-B) mediating escape swimming in Tritonia diomedea. Cells use a hybrid integrate-and-fire scheme pioneered by Peter Getting. Each model cell is reconstructed from extensive physiological measurements to precisely mimic I-F curves, synaptic waveforms, and functional connectivity.
Model Type: Realistic Network
Region(s) or Organism(s): Tritonia
Cell Type(s): Tritonia swim interneuron dorsal; Tritonia cerebral cell; Tritonia swim interneuron ventral
Currents: I A
Model Concept(s): Bursting; Oscillations; Invertebrate
Simulation Environment: NEURON
Implementer(s): Calin-Jageman, Robert [rcalinjageman at gsu dot edu]; Mensh, Brett ; Frost, William N; Katz, Paul S; Tunstall, Mark
References:
Calin-Jageman RJ, Tunstall MJ, Mensh BD, Katz PS, Frost WN. (2007). Parameter space analysis suggests multi-site plasticity contributes to motor pattern initiation in Tritonia. Journal of neurophysiology. 98 [PubMed]