Altomare C et al. (2003). Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node. The Journal of physiology. 549 [PubMed]
Basheer R, Strecker RE, Thakkar MM, McCarley RW. (2004). Adenosine and sleep-wake regulation. Progress in neurobiology. 73 [PubMed]
Budde T, Biella G, Munsch T, Pape HC. (1997). Lack of regulation by intracellular Ca2+ of the hyperpolarization-activated cation current in rat thalamic neurones. The Journal of physiology. 503 ( Pt 1) [PubMed]
Budde T et al. (2005). Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Campagna JA, Miller KW, Forman SA. (2003). Mechanisms of actions of inhaled anesthetics. The New England journal of medicine. 348 [PubMed]
Chen X et al. (2005). HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Day M et al. (2005). Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Detsch O, Kochs E, Siemers M, Bromm B, Vahle-Hinz C. (2002). Differential effects of isoflurane on excitatory and inhibitory synaptic inputs to thalamic neurones in vivo. British journal of anaesthesia. 89 [PubMed]
Dilger JP, Vidal AM, Mody HI, Liu Y. (1994). Evidence for direct actions of general anesthetics on an ion channel protein. A new look at a unified mechanism of action. Anesthesiology. 81 [PubMed]
Fanselow EE, Sameshima K, Baccala LA, Nicolelis MA. (2001). Thalamic bursting in rats during different awake behavioral states. Proceedings of the National Academy of Sciences of the United States of America. 98 [PubMed]
Franks NP, Lieb WR. (1994). Molecular and cellular mechanisms of general anaesthesia. Nature. 367 [PubMed]
Franks NP, Lieb WR. (1998). Which molecular targets are most relevant to general anaesthesia? Toxicology letters. 100-101 [PubMed]
Heurteaux C et al. (2004). TREK-1, a K+ channel involved in neuroprotection and general anesthesia. The EMBO journal. 23 [PubMed]
Hines ML, Carnevale NT. (2001). NEURON: a tool for neuroscientists. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 7 [PubMed]
Honoré E. (2007). The neuronal background K2P channels: focus on TREK1. Nature reviews. Neuroscience. 8 [PubMed]
Huguenard JR, McCormick DA. (1992). Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons. Journal of neurophysiology. 68 [PubMed]
Jones MV, Harrison NL. (1993). Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons. Journal of neurophysiology. 70 [PubMed]
Linden AM et al. (2006). The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists. The Journal of pharmacology and experimental therapeutics. 317 [PubMed]
Linden AM et al. (2007). TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics. The Journal of pharmacology and experimental therapeutics. 323 [PubMed]
Ludwig A et al. (2003). Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. The EMBO journal. 22 [PubMed]
Maingret F, Patel AJ, Lesage F, Lazdunski M, Honoré E. (1999). Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. The Journal of biological chemistry. 274 [PubMed]
McCormick DA. (1992). Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Progress in neurobiology. 39 [PubMed]
McCormick DA, Huguenard JR. (1992). A model of the electrophysiological properties of thalamocortical relay neurons. Journal of neurophysiology. 68 [PubMed]
McCormick DA, Pape HC. (1990). Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. The Journal of physiology. 431 [PubMed]
Meuth P et al. (2005). Get the rhythm: modeling neuronal activity. Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience. 4 [PubMed]
Meuth SG et al. (2006). The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. Molecular pharmacology. 69 [PubMed]
Meuth SG et al. (2003). Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]
Meuth SG et al. (2006). Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels. Journal of neurophysiology. 96 [PubMed]
Mihic SJ et al. (1997). Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389 [PubMed]
Mikulec AA, Pittson S, Amagasu SM, Monroe FA, MacIver MB. (1998). Halothane depresses action potential conduction in hippocampal axons. Brain research. 796 [PubMed]
Monteggia LM, Eisch AJ, Tang MD, Kaczmarek LK, Nestler EJ. (2000). Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain. Brain research. Molecular brain research. 81 [PubMed]
Much B et al. (2003). Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. The Journal of biological chemistry. 278 [PubMed]
Nelson LE et al. (2002). The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway. Nature neuroscience. 5 [PubMed]
Pape HC. (1992). Adenosine promotes burst activity in guinea-pig geniculocortical neurones through two different ionic mechanisms. The Journal of physiology. 447 [PubMed]
Pape HC. (1996). Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annual review of physiology. 58 [PubMed]
Pape HC, Budde T, Broicher T, Kanyshkova T. (2007). Developmental and functional profile of the thalamic hyperpolarizationactivated cation current, Ih, in absence epilepsy. Thalamus Related Systems DOI 10.1017-S1472928807000180.
Patel AJ et al. (1999). Inhalational anesthetics activate two-pore-domain background K+ channels. Nature neuroscience. 2 [PubMed]
Patel AJ, Lazdunski M. (2004). The 2P-domain K+ channels: role in apoptosis and tumorigenesis. Pflugers Archiv : European journal of physiology. 448 [PubMed]
Pearce RA. (1996). Volatile anaesthetic enhancement of paired-pulse depression investigated in the rat hippocampus in vitro. The Journal of physiology. 492 ( Pt 3) [PubMed]
Porkka-Heiskanen T, Alanko L, Kalinchuk A, Stenberg D. (2002). Adenosine and sleep. Sleep medicine reviews. 6 [PubMed]
Rajan S et al. (2001). THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. The Journal of biological chemistry. 276 [PubMed]
Ries CR, Puil E. (1999). Mechanism of anesthesia revealed by shunting actions of isoflurane on thalamocortical neurons. Journal of neurophysiology. 81 [PubMed]
Ries CR, Puil E. (1999). Ionic mechanism of isoflurane's actions on thalamocortical neurons. Journal of neurophysiology. 81 [PubMed]
Seifert R et al. (1999). Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]
Sherman SM, Guillery RW. (1996). Functional organization of thalamocortical relays. Journal of neurophysiology. 76 [PubMed]
Sherman SM, Guillery RW. (2001). Exploring the Thalamus.
Sirois JE, Lei Q, Talley EM, Lynch C, Bayliss DA. (2000). The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]
Sirois JE, Lynch C, Bayliss DA. (2002). Convergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones. The Journal of physiology. 541 [PubMed]
Steriade M. (1997). Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. Cerebral cortex (New York, N.Y. : 1991). 7 [PubMed]
Steriade M, Jones EG, McCormick DA. (1997). Thalamus.
Sugiyama K, Muteki T, Shimoji K. (1992). Halothane-induced hyperpolarization and depression of postsynaptic potentials of guinea pig thalamic neurons in vitro. Brain research. 576 [PubMed]
Talley EM, Bayliss DA. (2002). Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action. The Journal of biological chemistry. 277 [PubMed]
Talley EM, Solorzano G, Lei Q, Kim D, Bayliss DA. (2001). Cns distribution of members of the two-pore-domain (KCNK) potassium channel family. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]
Triner L, Vulliemoz Y, Woo SY, Verosky M. (1980). Halothane effect on cAMP generation and hydrolysis in rat brain. European journal of pharmacology. 66 [PubMed]
Trudell JR, Bertaccini E. (2002). Molecular modelling of specific and non-specific anaesthetic interactions. British journal of anaesthesia. 89 [PubMed]
Tung A, Mendelson WB. (2004). Anesthesia and sleep. Sleep medicine reviews. 8 [PubMed]
Vahle-Hinz C, Detsch O, Siemers M, Kochs E. (2007). Contributions of GABAergic and glutamatergic mechanisms to isoflurane-induced suppression of thalamic somatosensory information transfer. Experimental brain research. 176 [PubMed]
Weyand TG, Boudreaux M, Guido W. (2001). Burst and tonic response modes in thalamic neurons during sleep and wakefulness. Journal of neurophysiology. 85 [PubMed]
Carnevale NT, Morse TM. (1996). Research reports that have used NEURON Web published citations at the NEURON website.