Bader CR, Macleish PR, Schwartz EA. (1979). A voltage-clamp study of the light response in solitary rods of the tiger salamander. The Journal of physiology. 296 [PubMed]
Beaumont V, Zucker RS. (2000). Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels. Nature neuroscience. 3 [PubMed]
Brown H, Difrancesco D. (1980). Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node. The Journal of physiology. 308 [PubMed]
Brown HF, DiFrancesco D, Noble SJ. (1979). How does adrenaline accelerate the heart? Nature. 280 [PubMed]
Demontis GC, Longoni B, Barcaro U, Cervetto L. (1999). Properties and functional roles of hyperpolarization-gated currents in guinea-pig retinal rods. The Journal of physiology. 515 ( Pt 3) [PubMed]
DiFrancesco D. (1993). Pacemaker mechanisms in cardiac tissue. Annual review of physiology. 55 [PubMed]
DiFrancesco D, Ducouret P, Robinson RB. (1989). Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science (New York, N.Y.). 243 [PubMed]
DiFrancesco D, Mangoni M. (1994). Modulation of single hyperpolarization-activated channels (i(f)) by cAMP in the rabbit sino-atrial node. The Journal of physiology. 474 [PubMed]
DiFrancesco D, Tortora P. (1991). Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature. 351 [PubMed]
Franz O, Liss B, Neu A, Roeper J. (2000). Single-cell mRNA expression of HCN1 correlates with a fast gating phenotype of hyperpolarization-activated cyclic nucleotide-gated ion channels (Ih) in central neurons. The European journal of neuroscience. 12 [PubMed]
Goulding EH et al. (1992). Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons. Neuron. 8 [PubMed]
Ishii TM, Takano M, Xie LH, Noma A, Ohmori H. (1999). Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node. The Journal of biological chemistry. 274 [PubMed]
Jan LY, Jan YN. (1997). Cloned potassium channels from eukaryotes and prokaryotes. Annual review of neuroscience. 20 [PubMed]
Kandel ER, Siegelbaum SA, Nolan MF, Morozov A, Gibbs E. (2000). Contribution of HCN1 channels to H-current and membrane properties of CA1 pyramidal neurons. 803.2 Soc Neurosci Abstr.
Kentros C et al. (2000). Generation and characterization of mice harboring a knockout of the hyperpolarization-activated channel HCN1. 803.1 Soc Neurosci Abstr.
Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M. (1998). A family of hyperpolarization-activated mammalian cation channels. Nature. 393 [PubMed]
Ludwig A et al. (1999). Two pacemaker channels from human heart with profoundly different activation kinetics. The EMBO journal. 18 [PubMed]
Lüthi A, McCormick DA. (1998). H-current: properties of a neuronal and network pacemaker. Neuron. 21 [PubMed]
Maller JL, Butcher FR, Krebs EG. (1979). Early effect of progesterone on levels of cyclic adenosine 3':5'-monophosphate in Xenopus oocytes. The Journal of biological chemistry. 254 [PubMed]
Marbán E. (1999). Inaugural editorial: a new era for Circulation Research. Circulation research. 85 [PubMed]
McCormick DA, Pape HC. (1990). Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. The Journal of physiology. 431 [PubMed]
Monteggia LM, Eisch AJ, Tang MD, Kaczmarek LK, Nestler EJ. (2000). Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain. Brain research. Molecular brain research. 81 [PubMed]
Moosmang S, Biel M, Hofmann F, Ludwig A. (1999). Differential distribution of four hyperpolarization-activated cation channels in mouse brain. Biological chemistry. 380 [PubMed]
Pape HC. (1996). Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annual review of physiology. 58 [PubMed]
Santoro B et al. (2000). Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]
Santoro B, Grant SG, Bartsch D, Kandel ER. (1997). Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels. Proceedings of the National Academy of Sciences of the United States of America. 94 [PubMed]
Santoro B et al. (1998). Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell. 93 [PubMed]
Santoro B, Tibbs GR. (1999). The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels. Annals of the New York Academy of Sciences. 868 [PubMed]
Seifert R et al. (1999). Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]
Shabb JB, Corbin JD. (1992). Cyclic nucleotide-binding domains in proteins having diverse functions. The Journal of biological chemistry. 267 [PubMed]
Southan AP, Morris NP, Stephens GJ, Robertson B. (2000). Hyperpolarization-activated currents in presynaptic terminals of mouse cerebellar basket cells. The Journal of physiology. 526 Pt 1 [PubMed]
Su Y et al. (1995). Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science (New York, N.Y.). 269 [PubMed]
Tibbs GR, Liu DT, Leypold BG, Siegelbaum SA. (1998). A state-independent interaction between ligand and a conserved arginine residue in cyclic nucleotide-gated channels reveals a functional polarity of the cyclic nucleotide binding site. The Journal of biological chemistry. 273 [PubMed]
Ulens C, Tytgat J. (2001). Functional heteromerization of HCN1 and HCN2 pacemaker channels. The Journal of biological chemistry. 276 [PubMed]
Weber IT, Steitz TA. (1987). Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution. Journal of molecular biology. 198 [PubMed]
Zagotta WN, Siegelbaum SA. (1996). Structure and function of cyclic nucleotide-gated channels. Annual review of neuroscience. 19 [PubMed]
Anderson WD, Galván EJ, Mauna JC, Thiels E, Barrionuevo G. (2011). Properties and functional implications of I (h) in hippocampal area CA3 interneurons. Pflugers Archiv : European journal of physiology. 462 [PubMed]
Chan CS, Shigemoto R, Mercer JN, Surmeier DJ. (2004). HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]
Chen X, Shu S, Kennedy DP, Willcox SC, Bayliss DA. (2009). Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice. Journal of neurophysiology. 101 [PubMed]
Day M et al. (2005). Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Elinder F, Männikkö R, Pandey S, Larsson HP. (2006). Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels. The Journal of physiology. 575 [PubMed]
Mäki-Marttunen T, Mäki-Marttunen V. (2022). Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells PLoS computational biology. 18 [PubMed]
Neymotin SA, Dura-Bernal S, Lakatos P, Sanger TD, Lytton WW. (2016). Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex. Frontiers in pharmacology. 7 [PubMed]
Neymotin SA et al. (2013). Ih tunes theta/gamma oscillations and cross-frequency coupling in an in silico CA3 model. PloS one. 8 [PubMed]
Neymotin SA et al. (2016). Calcium regulation of HCN channels supports persistent activity in a multiscale model of neocortex. Neuroscience. 316 [PubMed]
Orio P et al. (2012). Role of Ih in the firing pattern of mammalian cold thermoreceptor endings. Journal of neurophysiology. 108 [PubMed]
Poolos NP, Migliore M, Johnston D. (2002). Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites. Nature neuroscience. 5 [PubMed]
Rich S, Moradi Chameh H, Sekulic V, Valiante TA, Skinner FK. (2021). Modeling Reveals Human-Rodent Differences in H-Current Kinetics Influencing Resonance in Cortical Layer 5 Neurons. Cerebral cortex (New York, N.Y. : 1991). 31 [PubMed]
Sekulić V, Chen TC, Lawrence JJ, Skinner FK. (2015). Dendritic distributions of I h channels in experimentally-derived multi-compartment models of oriens-lacunosum/moleculare (O-LM) hippocampal interneurons. Frontiers in synaptic neuroscience. 7 [PubMed]
Sherif MA, Neymotin SA, Lytton WW. (2020). In silico hippocampal modeling for multi-target pharmacotherapy in schizophrenia. NPJ schizophrenia. 6 [PubMed]
Wang J, Chen S, Nolan MF, Siegelbaum SA. (2002). Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling. Neuron. 36 [PubMed]