Antunes G, De Schutter E. (2012). A stochastic signaling network mediates the probabilistic induction of cerebellar long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

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References and models cited by this paper

Adesnik H, Nicoll RA, England PM. (2005). Photoinactivation of native AMPA receptors reveals their real-time trafficking. Neuron. 48 [PubMed]

Arkin A, Ross J, McAdams HH. (1998). Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells. Genetics. 149 [PubMed]

Bats C, Groc L, Choquet D. (2007). The interaction between Stargazin and PSD-95 regulates AMPA receptor surface trafficking. Neuron. 53 [PubMed]

Becskei A, Serrano L. (2000). Engineering stability in gene networks by autoregulation. Nature. 405 [PubMed]

Bhalla US. (2004). Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways. Biophysical journal. 87 [PubMed]

Bhalla US. (2004). Signaling in small subcellular volumes. II. Stochastic and diffusion effects on synaptic network properties. Biophysical journal. 87 [PubMed]

Bhalla US, Iyengar R. (1999). Emergent properties of networks of biological signaling pathways. Science (New York, N.Y.). 283 [PubMed]

Bittova L, Stahelin RV, Cho W. (2001). Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity. The Journal of biological chemistry. 276 [PubMed]

Borgdorff AJ, Choquet D. (2002). Regulation of AMPA receptor lateral movements. Nature. 417 [PubMed]

Cheng D et al. (2006). Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum. Molecular & cellular proteomics : MCP. 5 [PubMed]

Chung HJ, Steinberg JP, Huganir RL, Linden DJ. (2003). Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science (New York, N.Y.). 300 [PubMed]

Doi T, Kuroda S, Michikawa T, Kawato M. (2005). Inositol 1,4,5-trisphosphate-dependent Ca2+ threshold dynamics detect spike timing in cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Earnshaw BA, Bressloff PC. (2006). Biophysical model of AMPA receptor trafficking and its regulation during long-term potentiation/long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Ehlers MD. (2000). Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron. 28 [PubMed]

Eldar A, Elowitz MB. (2010). Functional roles for noise in genetic circuits. Nature. 467 [PubMed]

Elowitz MB, Levine AJ, Siggia ED, Swain PS. (2002). Stochastic gene expression in a single cell. Science (New York, N.Y.). 297 [PubMed]

Ferrell JE. (1996). Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. Trends in biochemical sciences. 21 [PubMed]

Ferrell JE. (2002). Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Current opinion in cell biology. 14 [PubMed]

Graupner M, Brunel N. (2007). STDP in a bistable synapse model based on CaMKII and associated signaling pathways. PLoS computational biology. 3 [PubMed]

Harris KM, Stevens JK. (1988). Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 8 [PubMed]

Hepburn I, Chen W, Wils S, De Schutter E. (2012). STEPS: efficient simulation of stochastic reaction-diffusion models in realistic morphologies. BMC systems biology. 6 [PubMed]

Higley MJ, Sabatini BL. (2008). Calcium signaling in dendrites and spines: practical and functional considerations. Neuron. 59 [PubMed]

Huang CY, Ferrell JE. (1996). Ultrasensitivity in the mitogen-activated protein kinase cascade. Proceedings of the National Academy of Sciences of the United States of America. 93 [PubMed]

Ito M. (2002). The molecular organization of cerebellar long-term depression. Nature reviews. Neuroscience. 3 [PubMed]

Jörntell H, Hansel C. (2006). Synaptic memories upside down: bidirectional plasticity at cerebellar parallel fiber-Purkinje cell synapses. Neuron. 52 [PubMed]

Kennedy MB, Beale HC, Carlisle HJ, Washburn LR. (2005). Integration of biochemical signalling in spines. Nature reviews. Neuroscience. 6 [PubMed]

Kolch W et al. (1993). Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature. 364 [PubMed]

Konnerth A, Dreessen J, Augustine GJ. (1992). Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 89 [PubMed]

Kotaleski JH, Blackwell KT. (2010). Modelling the molecular mechanisms of synaptic plasticity using systems biology approaches. Nature reviews. Neuroscience. 11 [PubMed]

Kuroda S, Schweighofer N, Kawato M. (2001). Exploration of signal transduction pathways in cerebellar long-term depression by kinetic simulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Launey T, Endo S, Sakai R, Harano J, Ito M. (2004). Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor. Proceedings of the National Academy of Sciences of the United States of America. 101 [PubMed]

Makino H, Malinow R. (2009). AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis. Neuron. 64 [PubMed]

Masugi-Tokita M et al. (2007). Number and density of AMPA receptors in individual synapses in the rat cerebellum as revealed by SDS-digested freeze-fracture replica labeling. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Matsuda S, Launey T, Mikawa S, Hirai H. (2000). Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons. The EMBO journal. 19 [PubMed]

Momiyama A et al. (2003). The density of AMPA receptors activated by a transmitter quantum at the climbing fibre-Purkinje cell synapse in immature rats. The Journal of physiology. 549 [PubMed]

Napper RM, Harvey RJ. (1988). Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. The Journal of comparative neurology. 274 [PubMed]

O'Connor DH, Wittenberg GM, Wang SS. (2005). Graded bidirectional synaptic plasticity is composed of switch-like unitary events. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

O'Flaherty JT, Chadwell BA, Kearns MW, Sergeant S, Daniel LW. (2001). Protein kinases C translocation responses to low concentrations of arachidonic acid. The Journal of biological chemistry. 276 [PubMed]

Passafaro M, Piëch V, Sheng M. (2001). Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons. Nature neuroscience. 4 [PubMed]

Peng J et al. (2004). Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. The Journal of biological chemistry. 279 [PubMed]

Petersen CC, Malenka RC, Nicoll RA, Hopfield JJ. (1998). All-or-none potentiation at CA3-CA1 synapses. Proceedings of the National Academy of Sciences of the United States of America. 95 [PubMed]

Piomelli D, Astarita G, Rapaka R. (2007). A neuroscientist's guide to lipidomics. Nature reviews. Neuroscience. 8 [PubMed]

Piomelli D et al. (1987). Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature. 328 [PubMed]

Raser JM, O'Shea EK. (2005). Noise in gene expression: origins, consequences, and control. Science (New York, N.Y.). 309 [PubMed]

Ribrault C, Sekimoto K, Triller A. (2011). From the stochasticity of molecular processes to the variability of synaptic transmission. Nature reviews. Neuroscience. 12 [PubMed]

Schmidt H, Eilers J. (2009). Spine neck geometry determines spino-dendritic cross-talk in the presence of mobile endogenous calcium binding proteins. Journal of computational neuroscience. 27 [PubMed]

Schmidt H, Stiefel KM, Racay P, Schwaller B, Eilers J. (2003). Mutational analysis of dendritic Ca2+ kinetics in rodent Purkinje cells: role of parvalbumin and calbindin D28k. The Journal of physiology. 551 [PubMed]

Sheng M, Hoogenraad CC. (2007). The postsynaptic architecture of excitatory synapses: a more quantitative view. Annual review of biochemistry. 76 [PubMed]

Simpson ML et al. (2009). Noise in biological circuits. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 1 [PubMed]

Sontag E et al. (1993). The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell. 75 [PubMed]

Steuber V et al. (2007). Cerebellar LTD and pattern recognition by Purkinje cells. Neuron. 54 [PubMed]

Suter DM et al. (2011). Mammalian genes are transcribed with widely different bursting kinetics. Science (New York, N.Y.). 332 [PubMed]

Tanaka K, Augustine GJ. (2008). A positive feedback signal transduction loop determines timing of cerebellar long-term depression. Neuron. 59 [PubMed]

Tanaka K et al. (2007). Ca2+ requirements for cerebellar long-term synaptic depression: role for a postsynaptic leaky integrator. Neuron. 54 [PubMed]

Tucker DE et al. (2009). Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function. The Journal of biological chemistry. 284 [PubMed]

Vecellio M, Schwaller B, Meyer M, Hunziker W, Celio MR. (2000). Alterations in Purkinje cell spines of calbindin D-28 k and parvalbumin knock-out mice. The European journal of neuroscience. 12 [PubMed]

Wang HX, Gerkin RC, Nauen DW, Bi GQ. (2005). Coactivation and timing-dependent integration of synaptic potentiation and depression. Nature neuroscience. 8 [PubMed]

Wang YT, Linden DJ. (2000). Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron. 25 [PubMed]

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Anwar H, Hepburn I, Nedelescu H, Chen W, De Schutter E. (2013). Stochastic calcium mechanisms cause dendritic calcium spike variability. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

Anwar H et al. (2014). Dendritic diameters affect the spatial variability of intracellular calcium dynamics in computer models. Frontiers in cellular neuroscience. 8 [PubMed]

Chen W, De Schutter E. (2014). Python-based geometry preparation and simulation visualization toolkits for STEPS. Frontiers in neuroinformatics. 8 [PubMed]

De Schutter E et al. (2017). A model of induction of cerebellar Long-Term Depression including RKIP inactivation of Raf and MEK Frontiers in Molecular Neuroscience.

Gallimore AR, Kim T, Tanaka-Yamamoto K, De Schutter E. (2018). Switching On Depression and Potentiation in the Cerebellum. Cell reports. 22 [PubMed]

Jȩdrzejewska-Szmek J, Luczak V, Abel T, Blackwell KT. (2017). ß-adrenergic signaling broadly contributes to LTP induction. PLoS computational biology. 13 [PubMed]

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