Buchin A, Chizhov A, Huberfeld G, Miles R, Gutkin BS. (2016). Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36 [PubMed]

• Subiculum network model with dynamic chloride/potassium homeostasis (Buchin et al 2016) [Model]

Doyon N et al. (2011). Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis. PLoS computational biology. 7 [PubMed]

Jedlicka P, Deller T, Gutkin BS, Backus KH. (2011). Activity-dependent intracellular chloride accumulation and diffusion controls GABA(A) receptor-mediated synaptic transmission. Hippocampus. 21 [PubMed]

• Effects of Chloride accumulation and diffusion on GABAergic transmission (Jedlicka et al 2011) [Model]

Kolbaev SN et al. (2020). NKCC-1 mediated Cl- uptake in immature CA3 pyramidal neurons is sufficient to compensate phasic GABAergic inputs. Scientific reports. 10 [PubMed]

• Cl- homeostasis in immature hippocampal CA3 neurons (Kolbaev et al 2020) [Model]

Lewin N, Aksay E, Clancy CE. (2012). Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons. PloS one. 7 [PubMed]

• Paradoxical GABA-mediated excitation (Lewin et al. 2012) [Model]

Lombardi A, Jedlicka P, Luhmann HJ, Kilb W. (2019). Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration International journal of molecular sciences. 20 [PubMed]

• Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019) [Model]

Prescott SA, Sejnowski TJ, De Koninck Y. (2006). Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain. Molecular pain. 2 [PubMed]

Ratté S, Prescott SA. (2011). ClC-2 channels regulate neuronal excitability, not intracellular chloride levels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

• ClC-2 channels regulate neuronal excitability, not intracellular Cl- levels (Ratte & Prescott 2011) [Model]

Sudhakar SK, Choi TJ, Ahmed OJ. (2019). Biophysical Modeling Suggests Optimal Drug Combinations for Improving the Efficacy of GABA Agonists after Traumatic Brain Injuries. Journal of neurotrauma. 36 [PubMed]

• Biophysical modeling of pathological brain states (Sudhakar et al 2019) [Model]