Akaike N, Inomata N, Tokutomi N. (1987). Contribution of chloride shifts to the fade of gamma-aminobutyric acid-gated currents in frog dorsal root ganglion cells. The Journal of physiology. 391 [PubMed]
Alger BE, Nicoll RA. (1979). GABA-mediated biphasic inhibitory responses in hippocampus. Nature. 281 [PubMed]
Alger BE, Nicoll RA. (1980). Spontaneous inhibitory post-synaptic potentials in hippocampus: mechanism for tonic inhibition. Brain research. 200 [PubMed]
Andersen P, Dingledine R, Gjerstad L, Langmoen IA, Laursen AM. (1980). Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid. The Journal of physiology. 305 [PubMed]
Atallah BV, Scanziani M. (2009). Instantaneous modulation of gamma oscillation frequency by balancing excitation with inhibition. Neuron. 62 [PubMed]
Backus KH, Deitmer JW, Friauf E. (1998). Glycine-activated currents are changed by coincident membrane depolarization in developing rat auditory brainstem neurones. The Journal of physiology. 507 ( Pt 3) [PubMed]
Barberis A, Petrini EM, Cherubini E. (2004). Presynaptic source of quantal size variability at GABAergic synapses in rat hippocampal neurons in culture. The European journal of neuroscience. 20 [PubMed]
Bazhenov M, Timofeev I, Fröhlich F, Sejnowski TJ. (2008). Cellular and network mechanisms of electrographic seizures. Drug discovery today. Disease models. 5 [PubMed]
Berglund K et al. (2008). Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain cell biology. 36 [PubMed]
Blaesse P, Airaksinen MS, Rivera C, Kaila K. (2009). Cation-chloride cotransporters and neuronal function. Neuron. 61 [PubMed]
Bonnet U, Bingmann D. (1995). GABAA-responses of CA3 neurones: contribution of bicarbonate and of Cl(-)-extrusion mechanisms. Neuroreport. 6 [PubMed]
Bormann J, Hamill OP, Sakmann B. (1987). Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. The Journal of physiology. 385 [PubMed]
Bracci E, Vreugdenhil M, Hack SP, Jefferys JG. (2001). Dynamic modulation of excitation and inhibition during stimulation at gamma and beta frequencies in the CA1 hippocampal region. Journal of neurophysiology. 85 [PubMed]
Bregestovski P, Waseem T, Mukhtarov M. (2009). Genetically encoded optical sensors for monitoring of intracellular chloride and chloride-selective channel activity. Frontiers in molecular neuroscience. 2 [PubMed]
Brumback AC, Staley KJ. (2008). Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]
Chance FS, Abbott LF, Reyes AD. (2002). Gain modulation from background synaptic input. Neuron. 35 [PubMed]
Cherubini E, Gaiarsa JL, Ben-Ari Y. (1991). GABA: an excitatory transmitter in early postnatal life. Trends in neurosciences. 14 [PubMed]
Cobb SR et al. (1999). Regulation of depolarizing GABA(A) receptor-mediated synaptic potentials by synaptic activation of GABA(B) autoreceptors in the rat hippocampus. Neuropharmacology. 38 [PubMed]
Dallwig R, Deitmer JW, Backus KH. (1999). On the mechanism of GABA-induced currents in cultured rat cortical neurons. Pflugers Archiv : European journal of physiology. 437 [PubMed]
De Schutter E, Smolen P. (1998). Calcium dynamics in large neuronal models Methods In Neuronal Modeling: From Ions To Networks.
DeFazio RA, Hablitz JJ. (2001). Chloride accumulation and depletion during GABA(A) receptor activation in neocortex. Neuroreport. 12 [PubMed]
De_schutter E. (). Modeling intracellular calcium dynamics Computational modeling methods for neuroscientists.
Destexhe A, Contreras D. (2006). Neuronal computations with stochastic network states. Science (New York, N.Y.). 314 [PubMed]
Duebel J et al. (2006). Two-photon imaging reveals somatodendritic chloride gradient in retinal ON-type bipolar cells expressing the biosensor Clomeleon. Neuron. 49 [PubMed]
Fatima-Shad K, Barry PH. (1993). Anion permeation in GABA- and glycine-gated channels of mammalian cultured hippocampal neurons. Proceedings. Biological sciences. 253 [PubMed]
Fiumelli H, Cancedda L, Poo MM. (2005). Modulation of GABAergic transmission by activity via postsynaptic Ca2+-dependent regulation of KCC2 function. Neuron. 48 [PubMed]
Frech MJ, Deitmer JW, Backus KH. (1999). Intracellular chloride and calcium transients evoked by gamma-aminobutyric acid and glycine in neurons of the rat inferior colliculus. Journal of neurobiology. 40 [PubMed]
Fujiwara-Tsukamoto Y, Isomura Y, Imanishi M, Fukai T, Takada M. (2007). Distinct types of ionic modulation of GABA actions in pyramidal cells and interneurons during electrical induction of hippocampal seizure-like network activity. The European journal of neuroscience. 25 [PubMed]
Gamba G. (2005). Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. Physiological reviews. 85 [PubMed]
Gavrikov KE, Nilson JE, Dmitriev AV, Zucker CL, Mangel SC. (2006). Dendritic compartmentalization of chloride cotransporters underlies directional responses of starburst amacrine cells in retina. Proceedings of the National Academy of Sciences of the United States of America. 103 [PubMed]
Glickfeld LL, Roberts JD, Somogyi P, Scanziani M. (2009). Interneurons hyperpolarize pyramidal cells along their entire somatodendritic axis. Nature neuroscience. 12 [PubMed]
Gulledge AT, Stuart GJ. (2003). Excitatory actions of GABA in the cortex. Neuron. 37 [PubMed]
Gulyás AI, Megías M, Emri Z, Freund TF. (1999). Total number and ratio of excitatory and inhibitory synapses converging onto single interneurons of different types in the CA1 area of the rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]
Herrero AI, Del Olmo N, González-Escalada JR, Solís JM. (2002). Two new actions of topiramate: inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance. Neuropharmacology. 42 [PubMed]
Hines ML, Carnevale NT. (2000). Expanding NEURON's repertoire of mechanisms with NMODL. Neural computation. 12 [PubMed]
Houston CM, Bright DP, Sivilotti LG, Beato M, Smart TG. (2009). Intracellular chloride ions regulate the time course of GABA-mediated inhibitory synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]
Huguenard JR, Alger BE. (1986). Whole-cell voltage-clamp study of the fading of GABA-activated currents in acutely dissociated hippocampal neurons. Journal of neurophysiology. 56 [PubMed]
Hull C, von Gersdorff H. (2004). Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. Neuron. 44 [PubMed]
Isomura Y et al. (2003). Synaptically activated Cl- accumulation responsible for depolarizing GABAergic responses in mature hippocampal neurons. Journal of neurophysiology. 90 [PubMed]
Jarolimek W, Lewen A, Misgeld U. (1999). A furosemide-sensitive K+-Cl- cotransporter counteracts intracellular Cl- accumulation and depletion in cultured rat midbrain neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]
Jedlicka P, Backus KH. (2006). Inhibitory transmission, activity-dependent ionic changes and neuronal network oscillations. Physiological research. 55 [PubMed]
Jeong HY, Gutkin B. (2005). Study on the role of GABAergic synapses in synchronization Neurocomputing. 65-66
Jin X, Huguenard JR, Prince DA. (2005). Impaired Cl- extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex. Journal of neurophysiology. 93 [PubMed]
Jones MV, Westbrook GL. (1995). Desensitized states prolong GABAA channel responses to brief agonist pulses. Neuron. 15 [PubMed]
Kaila K, Lamsa K, Smirnov S, Taira T, Voipio J. (1997). Long-lasting GABA-mediated depolarization evoked by high-frequency stimulation in pyramidal neurons of rat hippocampal slice is attributable to a network-driven, bicarbonate-dependent K+ transient. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]
Kaila K, Pasternack M, Saarikoski J, Voipio J. (1989). Influence of GABA-gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres. The Journal of physiology. 416 [PubMed]
Kaila K, Voipio J, Paalasmaa P, Pasternack M, Deisz RA. (1993). The role of bicarbonate in GABAA receptor-mediated IPSPs of rat neocortical neurones. The Journal of physiology. 464 [PubMed]
Kantrowitz JT, Francis NN, Salah A, Perkins KL. (2005). Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked. Journal of neurophysiology. 93 [PubMed]
Khirug S et al. (2008). GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]
Kuner T, Augustine GJ. (2000). A genetically encoded ratiometric indicator for chloride: capturing chloride transients in cultured hippocampal neurons. Neuron. 27 [PubMed]
Lamsa K, Taira T. (2003). Use-dependent shift from inhibitory to excitatory GABAA receptor action in SP-O interneurons in the rat hippocampal CA3 area. Journal of neurophysiology. 90 [PubMed]
Lee HH et al. (2007). Direct protein kinase C-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter KCC2. The Journal of biological chemistry. 282 [PubMed]
Ling DS, Benardo LS. (1995). Activity-dependent depression of monosynaptic fast IPSCs in hippocampus: contributions from reductions in chloride driving force and conductance. Brain research. 670 [PubMed]
Lopreore CL et al. (2008). Computational modeling of three-dimensional electrodiffusion in biological systems: application to the node of Ranvier. Biophysical journal. 95 [PubMed]
Mann EO, Kohl MM, Paulsen O. (2009). Distinct roles of GABA(A) and GABA(B) receptors in balancing and terminating persistent cortical activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]
Manuel NA, Davies CH. (1998). Pharmacological modulation of GABA(A) receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus. British journal of pharmacology. 125 [PubMed]
Marandi N, Konnerth A, Garaschuk O. (2002). Two-photon chloride imaging in neurons of brain slices. Pflugers Archiv : European journal of physiology. 445 [PubMed]
McCarren M, Alger BE. (1985). Use-dependent depression of IPSPs in rat hippocampal pyramidal cells in vitro. Journal of neurophysiology. 53 [PubMed]
Megías M, Emri Z, Freund TF, Gulyás AI. (2001). Total number and distribution of inhibitory and excitatory synapses on hippocampal CA1 pyramidal cells. Neuroscience. 102 [PubMed]
Mitchell SJ, Silver RA. (2003). Shunting inhibition modulates neuronal gain during synaptic excitation. Neuron. 38 [PubMed]
Morita K, Tsumoto K, Aihara K. (2006). Bidirectional modulation of neuronal responses by depolarizing GABAergic inputs. Biophysical journal. 90 [PubMed]
Mozrzymas JW, Zarnowska ED, Pytel M, Mercik K. (2003). Modulation of GABA(A) receptors by hydrogen ions reveals synaptic GABA transient and a crucial role of the desensitization process. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]
Nakanishi K, Kukita F. (2000). Intracellular [Cl(-)] modulates synchronous electrical activity in rat neocortical neurons in culture by way of GABAergic inputs. Brain research. 863 [PubMed]
Nusser Z, Kay LM, Laurent G, Homanics GE, Mody I. (2001). Disruption of GABA(A) receptors on GABAergic interneurons leads to increased oscillatory power in the olfactory bulb network. Journal of neurophysiology. 86 [PubMed]
Otis TS, Staley KJ, Mody I. (1991). Perpetual inhibitory activity in mammalian brain slices generated by spontaneous GABA release. Brain research. 545 [PubMed]
Patenaude C, Chapman CA, Bertrand S, Congar P, Lacaille JC. (2003). GABAB receptor- and metabotropic glutamate receptor-dependent cooperative long-term potentiation of rat hippocampal GABAA synaptic transmission. The Journal of physiology. 553 [PubMed]
Perez Velazquez JL. (2003). Bicarbonate-dependent depolarizing potentials in pyramidal cells and interneurons during epileptiform activity. The European journal of neuroscience. 18 [PubMed]
Perkins KL. (1999). Cl- accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells. Journal of neurophysiology. 82 [PubMed]
Perkins KL, Wong RK. (1996). Ionic basis of the postsynaptic depolarizing GABA response in hippocampal pyramidal cells. Journal of neurophysiology. 76 [PubMed]
Prescott SA, De Koninck Y. (2003). Gain control of firing rate by shunting inhibition: roles of synaptic noise and dendritic saturation. Proceedings of the National Academy of Sciences of the United States of America. 100 [PubMed]
Prescott SA, De_koninck Y, Doyon N, Kroger S. (2008). Impact of altered chloride extrusion capacity on cell excitability Program No. 237.17. Society for Neuroscience Abstract.
Prescott SA, Sejnowski TJ, De Koninck Y. (2006). Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain. Molecular pain. 2 [PubMed]
Qian N, Sejnowski TJ. (1990). When is an inhibitory synapse effective? Proceedings of the National Academy of Sciences of the United States of America. 87 [PubMed]
Rinke I, Artmann J, Stein V. (2010). ClC-2 voltage-gated channels constitute part of the background conductance and assist chloride extrusion. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]
Rivera C et al. (1999). The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature. 397 [PubMed]
Rudolph M, Pospischil M, Timofeev I, Destexhe A. (2007). Inhibition determines membrane potential dynamics and controls action potential generation in awake and sleeping cat cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]
Santhakumar V, Aradi I, Soltesz I. (2005). Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: a network model of the dentate gyrus incorporating cell types and axonal topography. Journal of neurophysiology. 93 [PubMed]
Saraga F, Balena T, Wolansky T, Dickson CT, Woodin MA. (2008). Inhibitory synaptic plasticity regulates pyramidal neuron spiking in the rodent hippocampus. Neuroscience. 155 [PubMed]
Schmidt-Hieber C, Jonas P, Bischofberger J. (2007). Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]
Sejnowski TJ, Qian N. (1989). An electro-diffusion model for computing membrane potentials and ionic concentrations in branching dendrites, spines and axons. Biol Cybern. 62
Shu Y, Hasenstaub A, McCormick DA. (2003). Turning on and off recurrent balanced cortical activity. Nature. 423 [PubMed]
Staley KJ, Proctor WR. (1999). Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport. The Journal of physiology. 519 Pt 3 [PubMed]
Staley KJ, Soldo BL, Proctor WR. (1995). Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science (New York, N.Y.). 269 [PubMed]
Steriade M. (2001). Impact of network activities on neuronal properties in corticothalamic systems. Journal of neurophysiology. 86 [PubMed]
Stiefel KM, Wespatat V, Gutkin B, Tennigkeit F, Singer W. (2005). Phase dependent sign changes of GABAergic synaptic input explored in-silicio and in-vitro. Journal of computational neuroscience. 19 [PubMed]
Sun MK, Zhao WQ, Nelson TJ, Alkon DL. (2001). Theta rhythm of hippocampal CA1 neuron activity: gating by GABAergic synaptic depolarization. Journal of neurophysiology. 85 [PubMed]
Thompson SM, Gähwiler BH. (1989). Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro. Journal of neurophysiology. 61 [PubMed]
Ulrich D. (2003). Differential arithmetic of shunting inhibition for voltage and spike rate in neocortical pyramidal cells. The European journal of neuroscience. 18 [PubMed]
Vida I, Bartos M, Jonas P. (2006). Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron. 49 [PubMed]
Viitanen T, Ruusuvuori E, Kaila K, Voipio J. (2010). The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus. The Journal of physiology. 588 [PubMed]
Vreugdenhil M, Bracci E, Jefferys JG. (2005). Layer-specific pyramidal cell oscillations evoked by tetanic stimulation in the rat hippocampal area CA1 in vitro and in vivo. The Journal of physiology. 562 [PubMed]
Wagner S, Sagiv N, Yarom Y. (2001). GABA-induced current and circadian regulation of chloride in neurones of the rat suprachiasmatic nucleus. The Journal of physiology. 537 [PubMed]
Woodin MA, Ganguly K, Poo MM. (2003). Coincident pre- and postsynaptic activity modifies GABAergic synapses by postsynaptic changes in Cl- transporter activity. Neuron. 39 [PubMed]
Buchin A, Chizhov A, Huberfeld G, Miles R, Gutkin BS. (2016). Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36 [PubMed]
Doyon N et al. (2011). Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis. PLoS computational biology. 7 [PubMed]
Kolbaev SN et al. (2020). NKCC-1 mediated Cl- uptake in immature CA3 pyramidal neurons is sufficient to compensate phasic GABAergic inputs. Scientific reports. 10 [PubMed]
Lombardi A, Jedlicka P, Luhmann HJ, Kilb W. (2019). Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration International journal of molecular sciences. 20 [PubMed]
Sudhakar SK, Choi TJ, Ahmed OJ. (2019). Biophysical Modeling Suggests Optimal Drug Combinations for Improving the Efficacy of GABA Agonists after Traumatic Brain Injuries. Journal of neurotrauma. 36 [PubMed]