ModelDB: Models that contain Apoptosis

Model Concept: Apoptosis

The process where a cell dies through a series of molecular signalling events, also called programmed cell death, either under normal or triggered by pathological states.

Biochemical Systems Theory Model of TNFa related pathways (Sasidharakurup and Diwakar 2020)
Boolean network-based analysis of the apoptosis network (Mai and Liu 2009)
Olfactory bulb network: neurogenetic restructuring and odor decorrelation (Chow et al. 2012)
Single-cell comprehensive biophysical model of SN pars compacta (Muddapu & Chakravarthy 2021)

Top authors for Apoptosis:

Sasidharakurup H (1)
Diwakar S (1)
Mai Z (1)
Liu H (1)
Chow SF (1)
Wick SD (1)
Riecke H (1)
Muddapu VR (1)
Chakravarthy VS (1)

Top concepts studied with Apoptosis:

Parkinson's (2)
Activity Patterns (2)
Aging/Alzheimer`s (1)
Methods (1)
Signaling pathways (1)
Boolean network (1)
Rate-coding model neurons (1)
Sensory processing (1)
Neurogenesis (1)
Olfaction (1)

Top neurons studied with Apoptosis:

Olfactory bulb main mitral GLU cell (1)
Olfactory bulb main interneuron granule MC GABA cell (1)
Substantia nigra pars compacta DA cell (1)

Top currents studied with Apoptosis:

Ca pump (1)
I A, slow (1)
I Ca,p (1)
I Calcium (1)
I h (1)
I K,Ca (1)
I K (1)
I Na, leak (1)
I_Na,Ca (1)
I_SERCA (1)

Top references cited by these models:

Woolf TB, Shepherd GM, Greer CA. (1991). Serial reconstructions of granule cell spines in the mammalian olfactory bulb. Synapse (New York, N.Y.). 7 (1)
Heeger DJ. (1992). Normalization of cell responses in cat striate cortex. Visual neuroscience. 9 (1)
Dolmetsch RE, Pajvani U, Fife K, Spotts JM, Greenberg ME. (2001). Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science (New York, N.Y.). 294 (1)
Friedrich RW, Laurent G. (2001). Dynamic optimization of odor representations by slow temporal patterning of mitral cell activity. Science (New York, N.Y.). 291 (1)
Cecchi GA, Petreanu LT, Alvarez-Buylla A, Magnasco MO. (2001). Unsupervised learning and adaptation in a model of adult neurogenesis. Journal of computational neuroscience. 11 (1)