Model Concept: Signaling pathways

The model is used to investigate signaling chemical pathways with kinetics.

  1. A kinetic model of dopamine- and calcium-dependent striatal synaptic plasticity (Nakano et al. 2010)
  2. A model of cerebellar LTD including RKIP inactivation of Raf and MEK (Hepburn et al 2017)
  3. A modified Morris-Lecar with TRPC4 & GIRK (Tian et al. 2022)
  4. A multiscale approach to analyze circadian rhythms (Vasalou & Henson, 2010) (CellML)
  5. A multiscale approach to analyze circadian rhythms (Vasalou & Henson, 2010) (SBML)
  6. A systems model of Parkinson’s disease using biochemical systems theory (Sasidharakurup et al. 2017)
  7. Active dendrites shape signaling microdomains in hippocampal neurons (Basak & Narayanan 2018)
  8. An allosteric kinetics of NMDARs in STDP (Urakubo et al. 2008)
  9. An integrative dynamic model of brain energy metabolism (Coultier et al 2009)
  10. Biochemical Systems Theory Model of SARS-CoV-2 infection network (Sasidharakurup et al., 2021)
  11. Boolean network-based analysis of the apoptosis network (Mai and Liu 2009)
  12. Ca(2+) oscillations based on Ca-induced Ca-release (Dupont et al 1991)
  13. Ca+/HCN channel-dependent persistent activity in multiscale model of neocortex (Neymotin et al 2016)
  14. CA1 oriens alveus interneurons: signaling properties (Minneci et al. 2007)
  15. CA1 pyramidal cell receptor dependent cAMP dynamics (Chay et al. 2016)
  16. Ca2+ oscillations in single astrocytes (Lavrentovich and Hemkin 2008) (python) (Manninen et al 2017)
  17. Ca2+ requirements for Long-Term Depression in Purkinje Cells (Criseida Zamora et al 2018)
  18. Calcium waves and mGluR-dependent synaptic plasticity in CA1 pyr. neurons (Ashhad & Narayanan 2013)
  19. CaMKII system exhibiting bistability with respect to calcium (Graupner and Brunel 2007)
  20. Cell signaling/ion channel variability effects on neuronal response (Anderson, Makadia, et al. 2015)
  21. Computational modeling of gephyrin-dependent inhibitory transsynaptic signaling (Lupascu et al 2020)
  22. Computational Modelling of TNFalpha Pathway in Parkinson's Disease (Sasidharakurup et al 2019)
  23. Dendritic spine geometry, spine apparatus organization: spatiotemporal Ca dynamics (Bell et al 2019)
  24. Differential interactions between Notch and ID factors control neurogenesis (Boareto et al 2017)
  25. Discrimination on behavioral time-scales mediated by reaction-diffusion in dendrites (Bhalla 2017)
  26. Dopamine activation of signaling pathways in a medium spiny projection neuron (Oliveira et al. 2012)
  27. Emergent properties of networks of biological signaling pathways (Bhalla, Iyengar 1999)
  28. Endocannabinoid dynamics gate spike-timing dependent depression and potentiation (Cui et al 2016)
  29. Endothelin action on pituitary latotrophs (Bertram et al. 2006)
  30. Excitation-contraction coupling/mitochondrial energetics (ECME) model (Cortassa et al. 2006)
  31. Firing neocortical layer V pyramidal neuron (Reetz et al. 2014; Stadler et al. 2014)
  32. Genetic, biochemical and bioelectrical dynamics in pattern regulation (Pietak & Levin 2017)
  33. Glutamate-evoked Ca2+ oscillations in single astrocytes (De Pitta et al. 2009) (Manninen et al 2017)
  34. Glutamate-evoked Ca2+ oscillations in single astrocytes (Modified from Dupont et al. 2011)
  35. Gq coupled signaling pathways involved in striatal synaptic plasticity (Kim et al. 2013)
  36. Hippocampus CA1: Simulations of LTP signaling pathways (Kim M et al. 2011)
  37. Hippocampus CA1: Temporal sensitivity of signaling pathways underlying LTP (Kim et al. 2010)
  38. Long term potentiation, LTP, protein synthesis, proteasome (Smolen et al. 2018)
  39. Model of a BDNF feedback loop (Zhang et al 2016)
  40. Model of AngII signaling and membrane electrophysiology (Makadia, Anderson, Fey et al., 2015)
  41. Model of calcium oscillations in olfactory cilia (Reidl et al. 2006)
  42. Model of DARPP-32 phosphorylation in striatal medium spiny neurons (Lindskog et al. 2006)
  43. Models of Na channels from a paper on the PKC control of I Na,P (Baker 2005)
  44. Moose/PyMOOSE: interoperable scripting in Python for MOOSE (Ray and Bhalla 2008)
  45. Multiscale model of olfactory receptor neuron in mouse (Dougherty 2009)
  46. Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)
  47. Paired turbulence and light effect on calcium increase in Hermissenda (Blackwell 2004)
  48. Regulation of KCNQ2/KCNQ3 current by G protein cycling (Suh et al 2004)
  49. Reproducibility and comparability of models for astrocyte Ca2+ excitability (Manninen et al 2017)
  50. Rescue of plasticity by a computationally predicted protocol (Liu et al. 2013)
  51. Roles of essential kinases in induction of late hippocampal LTP (Smolen et al., 2006)
  52. Signaling pathways In D1R containing striatal spiny projection neurons (Blackwell et al 2018)
  53. Signaling pathways underlying LTP in hippocampal CA1 pyramidal cells (Jedrzejewska-Szmek et al 2017)
  54. Simulation of calcium signaling in fine astrocytic processes (Denizot et al 2019)
  55. Spike timing detection in different forms of LTD (Doi et al 2005)
  56. Spontaneous calcium oscillations in astrocytes (Lavrentovich and Hemkin 2008)
  57. Spontaneous calcium oscillations in single astrocytes (Riera et al. 2011) (Manninen et al 2017)
  58. STDP and NMDAR Subunits (Gerkin et al. 2007)
  59. Stochastic model of the olfactory cilium transduction and adaptation (Antunes et al 2014)
  60. Strategy for kinase transport by microtubules to nerve terminals (Koon et al. 2014)
  61. Synchronization by D4 dopamine receptor-mediated phospholipid methylation (Kuznetsova, Deth 2008)
Top authors for Signaling pathways:
Top concepts studied with Signaling pathways:
Top neurons studied with Signaling pathways:
Top currents studied with Signaling pathways:
Top references cited by these models:
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.