ModelDB: Models that contain Virtual Cell

Simulation Environment: Virtual Cell

Note: this list includes both models hosted here at ModelDB and models where have metadata and link to the sourcecode somewhere else. These may also be viewed separately; see the browse by simulator page.

A nicotinic acetylcholine receptor kinetic model (Edelstein et al. 1996)
Calcium waves in neuroblastoma cells (Fink et al. 2000)
Phosphoinositide-Dependent Signaling in Sympathetic Neurons (SCG) (Kruse et al. 2016)
Regulation of KCNQ2/KCNQ3 current by G protein cycling (Suh et al 2004)

http://www.vcell.org
NRCAM, the National Resource for Cell Analysis and Modeling is developing a unique software modeling environment, the Virtual Cell, for quantitative cell biological research. NRCAM is currently funded through the NCRR, National Center for Research Resources, a component of the National Institutes of Health (NIH).

Top authors for Virtual Cell:

Hille B (2)
Edelstein SJ (1)
Schaad O (1)
Henry E (1)
Bertrand D (1)
Changeux JP (1)
Fink CC (1)
Slepchenko B (1)
Moraru II (1)
Watras J (1)

Top concepts studied with Virtual Cell:

Ion Channel Kinetics (2)
Calcium dynamics (1)
Calcium waves (1)
Signaling pathways (1)
G-protein coupled (1)

Top neurons studied with Virtual Cell:

Neuroblastoma (1)

Top currents studied with Virtual Cell:

I M (2)
I_SERCA (1)

Top references cited by these models:

Hirose K, Kadowaki S, Tanabe M, Takeshima H, Iino M. (1999). Spatiotemporal dynamics of inositol 1,4,5-trisphosphate that underlies complex Ca2+ mobilization patterns. Science (New York, N.Y.). 284 (3)
Zhang H, Craciun LC, Mirshahi T, Rohács T, Lopes CM, Jin T, Logothetis DE. (2003). PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron. 37 (3)
Cruzblanca H, Koh DS, Hille B. (1998). Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 95 (3)
Xu C, Watras J, Loew LM. (2003). Kinetic analysis of receptor-activated phosphoinositide turnover. The Journal of cell biology. 161 (3)
Suh BC, Hille B. (2002). Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron. 35 (3)