Thalamic neuron: Modeling rhythmic neuronal activity (Meuth et al. 2005)


The authors use an in vitro cell model of a single acutely isolated thalamic neuron in the NEURON simulation environment to address and discuss questions in an undergraduate course. Topics covered include passive electrical properties, composition of action potentials, trains of action potentials, multicompartment modeling, and research topics. The paper includes detailed instructions on how to run the simulations in the appendix.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Thalamus geniculate nucleus/lateral principal GLU cell

Currents: I Na,t; I L high threshold; I T low threshold; I A; I K; I h

Model Concept(s): Bursting; Tutorial/Teaching; Action Potentials

Simulation Environment: NEURON

References:

Meuth P et al. (2005). Get the rhythm: modeling neuronal activity. Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience. 4 [PubMed]


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