3D model of the olfactory bulb (Migliore et al. 2014)

This entry contains a link to a full HD version of movie 1 and the NEURON code of the paper: "Distributed organization of a brain microcircuit analysed by three-dimensional modeling: the olfactory bulb" by M Migliore, F Cavarretta, ML Hines, and GM Shepherd.

Model Type: Realistic Network; Channel/Receptor; Dendrite

Region(s) or Organism(s): Olfactory bulb

Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron granule MC GABA cell

Currents: I Na,t; I A; I K

Receptors: NMDA; Glutamate; Gaba

Model Concept(s): Pattern Recognition; Activity Patterns; Bursting; Temporal Pattern Generation; Oscillations; Synchronization; Active Dendrites; Detailed Neuronal Models; Synaptic Plasticity; Action Potentials; Synaptic Integration; Unsupervised Learning; Olfaction

Simulation Environment: NEURON

Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]; Migliore, Michele [Michele.Migliore at Yale.edu]; Cavarretta, Francesco [francescocavarretta at hotmail.it]

References:

Migliore M, Cavarretta F, Hines ML, Shepherd GM. (2014). Distributed organization of a brain microcircuit analyzed by three-dimensional modeling: the olfactory bulb. Frontiers in computational neuroscience. 8 [PubMed]