This model was published in Letzkus, Kampa & Stuart (2006) J Neurosci 26(41):10420-9. The simulation creates several plots showing voltage and NMDA current and conductance changes at different apical dendritic locations in layer 5 pyramidal neurons during STDP induction protocols. Created by B. Kampa (2006).
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Neocortex L5/6 pyramidal GLU cell
Currents: I L high threshold; I T low threshold; I A; I M; I K,Ca; I Sodium; I Calcium; I Potassium
Receptors: NMDA
Transmitters: Glutamate
Model Concept(s): Dendritic Action Potentials; Bursting; Active Dendrites; Synaptic Plasticity; Long-term Synaptic Plasticity; Action Potentials; STDP; Calcium dynamics
Simulation Environment: NEURON
Implementer(s): Kampa, Bjorn M [Bjoern.Kampa at anu.edu.au]
References:
Letzkus JJ, Kampa BM, Stuart GJ. (2006). Learning rules for spike timing-dependent plasticity depend on dendritic synapse location. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]