Ketamine disrupts theta modulation of gamma in a computer model of hippocampus (Neymotin et al 2011)


Neymotin SA et al. (2011). Ketamine Disrupts Theta Modulation of Gamma in a Computer Model of Hippocampus The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

See more from authors: Neymotin SA · Lazarewicz MT · Sherif M · Contreras D · Finkel LH · Lytton WW

References and models cited by this paper

Achim AM et al. (2007). Selective abnormal modulation of hippocampal activity during memory formation in first-episode psychosis. Archives of general psychiatry. 64 [PubMed]

Benes FM, Sorensen I, Bird ED. (1991). Reduced neuronal size in posterior hippocampus of schizophrenic patients. Schizophrenia bulletin. 17 [PubMed]

Bragin A et al. (1995). Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. 15 [PubMed]

Bresink I, Danysz W, Parsons CG, Mutschler E. (1995). Different binding affinities of NMDA receptor channel blockers in various brain regions--indication of NMDA receptor heterogeneity. Neuropharmacology. 34 [PubMed]

Bubeníková-Valesová V, Horácek J, Vrajová M, Höschl C. (2008). Models of schizophrenia in humans and animals based on inhibition of NMDA receptors. Neuroscience and biobehavioral reviews. 32 [PubMed]

Börgers C, Kopell N. (2003). Synchronization in networks of excitatory and inhibitory neurons with sparse, random connectivity. Neural computation. 15 [PubMed]

Canolty RT et al. (2006). High gamma power is phase-locked to theta oscillations in human neocortex. Science (New York, N.Y.). 313 [PubMed]

Cardin JA et al. (2009). Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature. 459 [PubMed]

Cobb SR et al. (1997). Synaptic effects of identified interneurons innervating both interneurons and pyramidal cells in the rat hippocampus. Neuroscience. 79 [PubMed]

Cull-Candy S, Brickley S, Farrant M. (2001). NMDA receptor subunits: diversity, development and disease. Current opinion in neurobiology. 11 [PubMed]

Cutsuridis V, Cobb S, Graham BP. (2010). Encoding and retrieval in a model of the hippocampal CA1 microcircuit. Hippocampus. 20 [PubMed]

Dean B, Scarr E, Bradbury R, Copolov D. (1999). Decreased hippocampal (CA3) NMDA receptors in schizophrenia. Synapse (New York, N.Y.). 32 [PubMed]

Destexhe A, Rudolph M, Paré D. (2003). The high-conductance state of neocortical neurons in vivo. Nature reviews. Neuroscience. 4 [PubMed]

Ehrlichman RS et al. (2009). N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience. 158 [PubMed]

Fries P, Nikolić D, Singer W. (2007). The gamma cycle. Trends in neurosciences. 30 [PubMed]

Goldberger AL et al. (2002). Fractal dynamics in physiology: alterations with disease and aging. Proceedings of the National Academy of Sciences of the United States of America. 99 Suppl 1 [PubMed]

Gourévitch B, Eggermont JJ. (2007). Evaluating information transfer between auditory cortical neurons. Journal of neurophysiology. 97 [PubMed]

Goutagny R, Jackson J, Williams S. (2009). Self-generated theta oscillations in the hippocampus. Nature neuroscience. 12 [PubMed]

Gray CM, Singer W. (1989). Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 86 [PubMed]

Greene R. (2001). Circuit analysis of NMDAR hypofunction in the hippocampus, in vitro, and psychosis of schizophrenia. Hippocampus. 11 [PubMed]

Grillner S, Markram H, De Schutter E, Silberberg G, LeBeau FE. (2005). Microcircuits in action--from CPGs to neocortex. Trends in neurosciences. 28 [PubMed]

Hangya B, Borhegyi Z, Szilágyi N, Freund TF, Varga V. (2009). GABAergic neurons of the medial septum lead the hippocampal network during theta activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Heckers S. (2001). Neuroimaging studies of the hippocampus in schizophrenia. Hippocampus. 11 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Hines ML, Carnevale NT. (2001). NEURON: a tool for neuroscientists. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 7 [PubMed]

Hines ML, Davison AP, Muller E. (2009). NEURON and Python. Frontiers in neuroinformatics. 3 [PubMed]

Holthausen EA et al. (2003). Long-term memory deficits in schizophrenia: primary or secondary dysfunction? Neuropsychology. 17 [PubMed]

Homayoun H, Moghaddam B. (2007). NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Honea R, Crow TJ, Passingham D, Mackay CE. (2005). Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. The American journal of psychiatry. 162 [PubMed]

Hong LE et al. (2010). Gamma and delta neural oscillations and association with clinical symptoms under subanesthetic ketamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 35 [PubMed]

Hájos N, Freund TF, Mody I. (2002). Comparison of single NMDA receptor channels recorded on hippocampal principal cells and oriens/alveus interneurons projecting to stratum lacunosum-moleculare (O-LM cells). Acta biologica Hungarica. 53 [PubMed]

Jackson ME, Homayoun H, Moghaddam B. (2004). NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 101 [PubMed]

Jahr CE, Stevens CF. (1990). Voltage dependence of NMDA-activated macroscopic conductances predicted by single-channel kinetics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 10 [PubMed]

Jessen F et al. (2003). Reduced hippocampal activation during encoding and recognition of words in schizophrenia patients. The American journal of psychiatry. 160 [PubMed]

Kelemen E, Fenton AA. (2010). Dynamic grouping of hippocampal neural activity during cognitive control of two spatial frames. PLoS biology. 8 [PubMed]

Kolomeets NS, Orlovskaya DD, Uranova NA. (2007). Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia. Synapse (New York, N.Y.). 61 [PubMed]

Lazarewicz MT et al. (2010). Ketamine modulates theta and gamma oscillations. Journal of cognitive neuroscience. 22 [PubMed]

Lisman J, Buzsáki G. (2008). A neural coding scheme formed by the combined function of gamma and theta oscillations. Schizophrenia bulletin. 34 [PubMed]

Lisman JE et al. (2008). Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends in neurosciences. 31 [PubMed]

Lytton WW. (2006). Neural Query System: Data-mining from within the NEURON simulator. Neuroinformatics. 4 [PubMed]

Lytton WW. (2008). Computer modelling of epilepsy. Nature reviews. Neuroscience. 9 [PubMed]

Lytton WW, Sejnowski TJ. (1991). Simulations of cortical pyramidal neurons synchronized by inhibitory interneurons. Journal of neurophysiology. 66 [PubMed]

Malhotra AK et al. (1997). Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 17 [PubMed]

Malhotra AK et al. (1996). NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 14 [PubMed]

Narr KL et al. (2004). Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage. 21 [PubMed]

Newcomer JW et al. (1999). Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 20 [PubMed]

Neymotin SA, Jacobs KM, Fenton AA, Lytton WW. (2011). Synaptic information transfer in computer models of neocortical columns. Journal of computational neuroscience. 30 [PubMed]

Neymotin SA, Lee H, Park E, Fenton AA, Lytton WW. (2011). Emergence of physiological oscillation frequencies in a computer model of neocortex. Frontiers in computational neuroscience. 5 [PubMed]

Nyíri G, Stephenson FA, Freund TF, Somogyi P. (2003). Large variability in synaptic N-methyl-D-aspartate receptor density on interneurons and a comparison with pyramidal-cell spines in the rat hippocampus. Neuroscience. 119 [PubMed]

Olypher AV, Klement D, Fenton AA. (2006). Cognitive disorganization in hippocampus: a physiological model of the disorganization in psychosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Orbán G, Kiss T, Erdi P. (2006). Intrinsic and synaptic mechanisms determining the timing of neuron population activity during hippocampal theta oscillation. Journal of neurophysiology. 96 [PubMed]

Parnas J, Bovet P, Zahavi D. (2002). Schizophrenic autism: clinical phenomenology and pathogenetic implications. World psychiatry : official journal of the World Psychiatric Association (WPA). 1 [PubMed]

Phillips WA, Silverstein SM. (2003). Convergence of biological and psychological perspectives on cognitive coordination in schizophrenia. The Behavioral and brain sciences. 26 [PubMed]

Silberberg G, Grillner S, LeBeau FE, Maex R, Markram H. (2005). Synaptic pathways in neural microcircuits. Trends in neurosciences. 28 [PubMed]

Stacey WC, Lazarewicz MT, Litt B. (2009). Synaptic noise and physiological coupling generate high-frequency oscillations in a hippocampal computational model. Journal of neurophysiology. 102 [PubMed]

Stewart M, Fox SE. (1990). Do septal neurons pace the hippocampal theta rhythm? Trends in neurosciences. 13 [PubMed]

Suzuki Y, Jodo E, Takeuchi S, Niwa S, Kayama Y. (2002). Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons in freely moving rats. Neuroscience. 114 [PubMed]

Szeszko PR et al. (2003). Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia. The American journal of psychiatry. 160 [PubMed]

Tamminga CA, Stan AD, Wagner AD. (2010). The hippocampal formation in schizophrenia. The American journal of psychiatry. 167 [PubMed]

Tiesinga P, Sejnowski TJ. (2009). Cortical enlightenment: are attentional gamma oscillations driven by ING or PING? Neuron. 63 [PubMed]

Tort AB, Rotstein HG, Dugladze T, Gloveli T, Kopell NJ. (2007). On the formation of gamma-coherent cell assemblies by oriens lacunosum-moleculare interneurons in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]

Uhlhaas PJ, Phillips WA, Mitchell G, Silverstein SM. (2006). Perceptual grouping in disorganized schizophrenia. Psychiatry research. 145 [PubMed]

Uhlhaas PJ, Phillips WA, Schenkel LS, Silverstein SM. (2006). Theory of mind and perceptual context-processing in schizophrenia. Cognitive neuropsychiatry. 11 [PubMed]

Uhlhaas PJ, Silverstein SM. (2005). Perceptual organization in schizophrenia spectrum disorders: empirical research and theoretical implications. Psychological bulletin. 131 [PubMed]

Uhlhaas PJ, Singer W. (2006). Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology. Neuron. 52 [PubMed]

Wang XJ. (2002). Pacemaker neurons for the theta rhythm and their synchronization in the septohippocampal reciprocal loop. Journal of neurophysiology. 87 [PubMed]

Wang XJ, Buzsáki G. (1996). Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

White JA, Banks MI, Pearce RA, Kopell NJ. (2000). Networks of interneurons with fast and slow gamma-aminobutyric acid type A (GABAA) kinetics provide substrate for mixed gamma-theta rhythm. Proceedings of the National Academy of Sciences of the United States of America. 97 [PubMed]

Whittington MA, Traub RD, Kopell N, Ermentrout B, Buhl EH. (2000). Inhibition-based rhythms: experimental and mathematical observations on network dynamics. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 38 [PubMed]

Zaidel DW, Esiri MM, Harrison PJ. (1997). Size, shape, and orientation of neurons in the left and right hippocampus: investigation of normal asymmetries and alterations in schizophrenia. The American journal of psychiatry. 154 [PubMed]

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