The model demonstrates how signal amplification with NMDARs depends on the synaptic environment. When direction selectivity (DS) detection is mediated by DS inhibition, NMDARs multiply other synaptic conductances. In the case of DS tuned excitation, NMDARs contribute additively.
Cell Type(s): Retina ganglion GLU cell
Simulation Environment: NEURON
Implementer(s): Polsky, Alon [alonpol at tx.technion.ac.il]