Changes of ionic concentrations during seizure transitions (Gentiletti et al. 2016)


Gentiletti D, Suffczynski P, Gnatkovsky V, de Curtis M. (2017). Changes of Ionic Concentrations During Seizure Transitions - A Modeling Study. International journal of neural systems. 27 [PubMed]

See more from authors: Gentiletti D · Suffczynski P · Gnatkovsky V · de Curtis M

References and models cited by this paper

Amzica F, Massimini M, Manfridi A. (2002). Spatial buffering during slow and paroxysmal sleep oscillations in cortical networks of glial cells in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Bazhenov M, Timofeev I, Steriade M, Sejnowski TJ. (2004). Potassium model for slow (2-3 Hz) in vivo neocortical paroxysmal oscillations. Journal of neurophysiology. 92 [PubMed]

Cressman JR, Ullah G, Ziburkus J, Schiff SJ, Barreto E. (2009). The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. Journal of computational neuroscience. 26 [PubMed]

Dietzel I, Heinemann U, Hofmeier G, Lux HD. (1982). Stimulus-induced changes in extracellular Na+ and Cl- concentration in relation to changes in the size of the extracellular space. Experimental brain research. 46 [PubMed]

Fransen E, Alonso AA, Hasselmo ME. (2002). Simulations of the role of the muscarinic-activated calcium-sensitive nonspecific cation current INCM in entorhinal neuronal activity during delayed matching tasks. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Gnatkovsky V, Librizzi L, Trombin F, de Curtis M. (2008). Fast activity at seizure onset is mediated by inhibitory circuits in the entorhinal cortex in vitro. Annals of neurology. 64 [PubMed]

Halnes G, Ostby I, Pettersen KH, Omholt SW, Einevoll GT. (2013). Electrodiffusive model for astrocytic and neuronal ion concentration dynamics. PLoS computational biology. 9 [PubMed]

Jefferys JG, Haas HL. (1982). Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission. Nature. 300 [PubMed]

Jensen MS, Azouz R, Yaari Y. (1994). Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium. Journal of neurophysiology. 71 [PubMed]

Jensen MS, Yaari Y. (1988). The relationship between interictal and ictal paroxysms in an in vitro model of focal hippocampal epilepsy. Annals of neurology. 24 [PubMed]

Johnston D, Wu SMS. (1995). Foundations of Cellular Neurophysiology with simulations and illustrations by Richard Gray Foundations of Cellular Neurophysiology.

Kager H, Wadman WJ, Somjen GG. (2000). Simulated seizures and spreading depression in a neuron model incorporating interstitial space and ion concentrations. Journal of neurophysiology. 84 [PubMed]

Kager H, Wadman WJ, Somjen GG. (2002). Conditions for the triggering of spreading depression studied with computer simulations. Journal of neurophysiology. 88 [PubMed]

Kager H, Wadman WJ, Somjen GG. (2007). Seizure-like afterdischarges simulated in a model neuron. Journal of computational neuroscience. 22 [PubMed]

Konnerth A, Heinemann U, Yaari Y. (1986). Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium. Journal of neurophysiology. 56 [PubMed]

Krishnan GP, Bazhenov M. (2011). Ionic dynamics mediate spontaneous termination of seizures and postictal depression state. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Lauf PK, Adragna NC. (2000). K-Cl cotransport: properties and molecular mechanism. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 10 [PubMed]

Lee J. (2007). Fast Rhythmic Bursting Cells: The Horizontal Fiber System in the Cat’s Primary Visual Cortex Penn McNair Research Journal. 1(1)

Magistretti J, Alonso A. (1999). Biophysical properties and slow voltage-dependent inactivation of a sustained sodium current in entorhinal cortex layer-II principal neurons: a whole-cell and single-channel study. The Journal of general physiology. 114 [PubMed]

McCormick DA, Contreras D. (2001). On the cellular and network bases of epileptic seizures. Annual review of physiology. 63 [PubMed]

McLaughlin SG, Szabo G, Eisenman G. (1971). Divalent ions and the surface potential of charged phospholipid membranes. The Journal of general physiology. 58 [PubMed]

Meeks JP, Mennerick S. (2004). Selective effects of potassium elevations on glutamate signaling and action potential conduction in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]

Nicholson C, Syková E. (1998). Extracellular space structure revealed by diffusion analysis. Trends in neurosciences. 21 [PubMed]

Owen JA, Barreto E, Cressman JR. (2013). Controlling seizure-like events by perturbing ion concentration dynamics with periodic stimulation. PloS one. 8 [PubMed]

Park EH, Durand DM. (2006). Role of potassium lateral diffusion in non-synaptic epilepsy: a computational study. Journal of theoretical biology. 238 [PubMed]

Park EH, Feng Z, Durand DM. (2008). Diffusive coupling and network periodicity: a computational study. Biophysical journal. 95 [PubMed]

Payne JA, Rivera C, Voipio J, Kaila K. (2003). Cation-chloride co-transporters in neuronal communication, development and trauma. Trends in neurosciences. 26 [PubMed]

Pumain R, Menini C, Heinemann U, Louvel J, Silva-Barrat C. (1985). Chemical synaptic transmission is not necessary for epileptic seizures to persist in the baboon Papio papio. Experimental neurology. 89 [PubMed]

Raimondo JV, Burman RJ, Katz AA, Akerman CJ. (2015). Ion dynamics during seizures. Frontiers in cellular neuroscience. 9 [PubMed]

Reiss M, Roberts MM, Monger G. (2000). Advanced Biology.

Sah P, Gibb AJ, Gage PW. (1988). Potassium current activated by depolarization of dissociated neurons from adult guinea pig hippocampus. The Journal of general physiology. 92 [PubMed]

Somjen GG. (2004). Ions in the brain: Normal function, seizures and stroke.

Somjen GG, Kager H, Wadman WJ. (2008). Computer simulations of neuron-glia interactions mediated by ion flux. Journal of computational neuroscience. 25 [PubMed]

Staley KJ, Soldo BL, Proctor WR. (1995). Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science (New York, N.Y.). 269 [PubMed]

Traub RD, Jefferys JG, Miles R, Whittington MA, Tóth K. (1994). A branching dendritic model of a rodent CA3 pyramidal neurone. The Journal of physiology. 481 ( Pt 1) [PubMed]

Traub RD, Wong RK, Miles R, Michelson H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology. 66 [PubMed]

Ullah G, Wei Y, Dahlem MA, Wechselberger M, Schiff SJ. (2015). The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization. PLoS computational biology. 11 [PubMed]

Uva L et al. (2008). Acute induction of epileptiform discharges by pilocarpine in the in vitro isolated guinea-pig brain requires enhancement of blood-brain barrier permeability. Neuroscience. 151 [PubMed]

Wei Y, Ullah G, Ingram J, Schiff SJ. (2014). Oxygen and seizure dynamics: II. Computational modeling. Journal of neurophysiology. 112 [PubMed]

Wei Y, Ullah G, Schiff SJ. (2014). Unification of neuronal spikes, seizures, and spreading depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Zhang M et al. (2014). Propagation of epileptiform activity can be independent of synaptic transmission, gap junctions, or diffusion and is consistent with electrical field transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Zhang ZJ et al. (2012). Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32 [PubMed]

de Almeida AC et al. (2008). Mechanistic hypotheses for nonsynaptic epileptiform activity induction and its transition from the interictal to ictal state--computational simulation. Epilepsia. 49 [PubMed]

de Curtis M, Gnatkovsky V. (2009). Reevaluating the mechanisms of focal ictogenesis: The role of low-voltage fast activity. Epilepsia. 50 [PubMed]

de Curtis M, Manfridi A, Biella G. (1998). Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

References and models that cite this paper

Sætra MJ, Einevoll GT, Halnes G. (2021). An electrodiffusive neuron-extracellular-glia model for exploring the genesis of slow potentials in the brain PLoS computational biology. 17 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.