" ... In this paper, we describe an MPI-based, parallel operator-splitting implementation for stochastic spatial reaction-diffusion simulations with irregular tetrahedral meshes. The performance of our implementation is first examined and analyzed with simulations of a simple model. We then demonstrate its application to real-world research by simulating the reaction-diffusion components of a published calcium burst model in both Purkinje neuron sub-branch and full dendrite morphologies..."
Region(s) or Organism(s): Cerebellum
Cell Type(s): Cerebellum Purkinje GABA cell
Model Concept(s): Bursting; Reaction-diffusion; Calcium dynamics; Methods
Simulation Environment: STEPS
Implementer(s): Chen, Weiliang [w.chen at oist.jp]
References:
Chen W, De Schutter E. (2017). Parallel STEPS: Large Scale Stochastic Spatial Reaction-Diffusion Simulation with High Performance Computers. Frontiers in neuroinformatics. 11 [PubMed]