Layer V pyramidal cell functions and schizophrenia genetics (Mäki-Marttunen et al 2019)


Mäki-Marttunen T et al. (2019). Computational modeling of genetic contributions to excitability and neural coding in layer V pyramidal cells: applications to schizophrenia pathology Front. Comput. Neurosci.. 13

See more from authors: Mäki-Marttunen T · Devor A · Phillips WA · Dale AM · Andreassen OA · Einevoll GT

References and models cited by this paper

Anastassiou CA, Perin R, Markram H, Koch C. (2011). Ephaptic coupling of cortical neurons. Nature neuroscience. 14 [PubMed]

Artola A, Singer W. (1993). Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation. Trends in neurosciences. 16 [PubMed]

Azizan EA et al. (2013). Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature genetics. 45 [PubMed]

Ballesteros-Merino C et al. (2014). Differential subcellular localization of SK3-containing channels in the hippocampus. The European journal of neuroscience. 39 [PubMed]

Bock G et al. (2011). Functional properties of a newly identified C-terminal splice variant of Cav1.3 L-type Ca2+ channels. The Journal of biological chemistry. 286 [PubMed]

Brackenbury WJ, Isom LL. (2011). Na Channel ß Subunits: Overachievers of the Ion Channel Family. Frontiers in pharmacology. 2 [PubMed]

Carlén M et al. (2012). A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior. Molecular psychiatry. 17 [PubMed]

Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J. (2005). International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacological reviews. 57 [PubMed]

Cestèle S et al. (2013). Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine. Epilepsia. 54 [PubMed]

Cestèle S et al. (2008). Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Christensen BK, Spencer JM, King JP, Sekuler AB, Bennett PJ. (2013). Noise as a mechanism of anomalous face processing among persons with Schizophrenia. Frontiers in psychology. 4 [PubMed]

Cordeiro JM et al. (2009). Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome. Journal of molecular and cellular cardiology. 46 [PubMed]

Depil K et al. (2011). Timothy mutation disrupts the link between activation and inactivation in Ca(V)1.2 protein. The Journal of biological chemistry. 286 [PubMed]

Devor A et al. (2017). Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia. Molecular psychiatry. 22 [PubMed]

Duan AR et al. (2015). Delta frequency optogenetic stimulation of the thalamic nucleus reuniens is sufficient to produce working memory deficits: relevance to schizophrenia. Biological psychiatry. 77 [PubMed]

Empson RM, Akemann W, Knöpfel T. (2010). The role of the calcium transporter protein plasma membrane calcium ATPase PMCA2 in cerebellar Purkinje neuron function. Functional neurology. 25 [PubMed]

Fakira AK et al. (2012). Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice. Molecular and cellular neurosciences. 51 [PubMed]

Ficarella R et al. (2007). A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]

Giacomello M et al. (2011). Mutations in PMCA2 and hereditary deafness: a molecular analysis of the pump defect. Cell calcium. 50 [PubMed]

Gomora JC, Murbartián J, Arias JM, Lee JH, Perez-Reyes E. (2002). Cloning and expression of the human T-type channel Ca(v)3.3: insights into prepulse facilitation. Biophysical journal. 83 [PubMed]

Green EK et al. (2010). The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Molecular psychiatry. 15 [PubMed]

Grienberger C et al. (2012). Sound-evoked network calcium transients in mouse auditory cortex in vivo. The Journal of physiology. 590 [PubMed]

Hay E, Hill S, Schürmann F, Markram H, Segev I. (2011). Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties. PLoS computational biology. 7 [PubMed]

Hohaus A et al. (2005). Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder. The Journal of biological chemistry. 280 [PubMed]

Hu D et al. (2010). Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome. Pacing and clinical electrophysiology : PACE. 33 [PubMed]

Ishii TM, Nakashima N, Ohmori H. (2007). Tryptophan-scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation. The Journal of physiology. 579 [PubMed]

Isom LL, De Jongh KS, Catterall WA. (1994). Auxiliary subunits of voltage-gated ion channels. Neuron. 12 [PubMed]

Ji Y et al. (2000). Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function. The Journal of biological chemistry. 275 [PubMed]

Jolivet R et al. (2008). The quantitative single-neuron modeling competition. Biological cybernetics. 99 [PubMed]

Keogh E, Lonardi S, Ratanamahatana CA. (2004). Towards parameter-free data mining Proceedings Of The Tenth ACM SIGKDD International Conference On Knowledge Discovery And Data Mining.

Kudrnac M et al. (2009). Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2. The Journal of biological chemistry. 284 [PubMed]

Li M, Chen X, Li X, Ma B, Vitány PMB. (2004). The similarity metric IEEE Transactions On Information Theory. 50

Lieb A, Scharinger A, Sartori S, Sinnegger-Brauns MJ, Striessnig J. (2012). Structural determinants of CaV1.3 L-type calcium channel gating. Channels (Austin, Tex.). 6 [PubMed]

Link S et al. (2009). Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart. The Journal of biological chemistry. 284 [PubMed]

Lőrincz ML et al. (2015). A distinct class of slow (~0.2-2 Hz) intrinsically bursting layer 5 pyramidal neurons determines UP/DOWN state dynamics in the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35 [PubMed]

Ma JY, Catterall WA, Scheuer T. (1997). Persistent sodium currents through brain sodium channels induced by G protein betagamma subunits. Neuron. 19 [PubMed]

Mantegazza M et al. (2005). Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

Massa E, Kelly KM, Yule DI, MacDonald RL, Uhler MD. (1995). Comparison of fura-2 imaging and electrophysiological analysis of murine calcium channel alpha 1 subunits coexpressed with novel beta 2 subunit isoforms. Molecular pharmacology. 47 [PubMed]

Metzner C, Schweikard A, Zurowski B. (2016). Multifactorial Modeling of Impairment of Evoked Gamma Range Oscillations in Schizophrenia. Frontiers in computational neuroscience. 10 [PubMed]

Murbartián J, Arias JM, Perez-Reyes E. (2004). Functional impact of alternative splicing of human T-type Cav3.3 calcium channels. Journal of neurophysiology. 92 [PubMed]

Mäki-Marttunen T et al. (2011). Information diversity in structure and dynamics of simulated neuronal networks. Frontiers in computational neuroscience. 5 [PubMed]

Mäki-Marttunen T et al. (2018). A stepwise neuron model fitting procedure designed for recordings with high spatial resolution: Application to layer 5 pyramidal cells. Journal of neuroscience methods. 293 [PubMed]

Mäki-Marttunen T et al. (2016). Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. 1 [PubMed]

Mäki-Marttunen T, Kesseli J, Nykter M. (2013). Balance between noise and information flow maximizes set complexity of network dynamics. PloS one. 8 [PubMed]

Nakazawa K et al. (2012). GABAergic interneuron origin of schizophrenia pathophysiology. Neuropharmacology. 62 [PubMed]

Neske GT, Connors BW. (2016). Distinct Roles of SOM and VIP Interneurons during Cortical Up States. Frontiers in neural circuits. 10 [PubMed]

Olney JW, Newcomer JW, Farber NB. (1999). NMDA receptor hypofunction model of schizophrenia. Journal of psychiatric research. 33 [PubMed]

Phillips WA, Larkum ME, Harley CW, Silverstein SM. (2016). The effects of arousal on apical amplification and conscious state. Neuroscience of consciousness. 2016 [PubMed]

Pinggera A et al. (2015). CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels. Biological psychiatry. 77 [PubMed]

Poirazi P, Brannon T, Mel BW. (2003). Pyramidal neuron as two-layer neural network. Neuron. 37 [PubMed]

Pérez-Alvarez A, Hernández-Vivanco A, Caba-González JC, Albillos A. (2011). Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells. Journal of neurochemistry. 116 [PubMed]

Ripke S et al. (2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature genetics. 45 [PubMed]

Saha S, Chant D, Welham J, McGrath J. (2005). A systematic review of the prevalence of schizophrenia. PLoS medicine. 2 [PubMed]

Sanchez-Vives MV, McCormick DA. (2000). Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nature neuroscience. 3 [PubMed]

Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature. 511 [PubMed]

Shadlen MN, Newsome WT. (1998). The variable discharge of cortical neurons: implications for connectivity, computation, and information coding. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Silverstein SM, Wibral M, Phillips WA. (2017). Implications of Information Theory for Computational Modeling of Schizophrenia. Computational psychiatry (Cambridge, Mass.). 1 [PubMed]

Smolin B, Karry R, Gal-Ben-Ari S, Ben-Shachar D. (2012). Differential expression of genes encoding neuronal ion-channel subunits in major depression, bipolar disorder and schizophrenia: implications for pathophysiology. The international journal of neuropsychopharmacology. 15 [PubMed]

Spitzer M, Neumann M. (1996). Noise in models of neurological and psychiatric disorders. International journal of neural systems. 7 [PubMed]

Sponheim SR, Clementz BA, Iacono WG, Beiser M. (1994). Resting EEG in first-episode and chronic schizophrenia. Psychophysiology. 31 [PubMed]

Stary A et al. (2008). Molecular dynamics and mutational analysis of a channelopathy mutation in the IIS6 helix of Ca V 1.2. Channels (Austin, Tex.). 2 [PubMed]

Stocker M. (2004). Ca(2+)-activated K+ channels: molecular determinants and function of the SK family. Nature reviews. Neuroscience. 5 [PubMed]

Sun Z, Williams DJ, Xu B, Gogos JA. (2018). Altered function and maturation of primary cortical neurons from a 22q11.2 deletion mouse model of schizophrenia. Translational psychiatry. 8 [PubMed]

Tan BZ et al. (2011). Functional characterization of alternative splicing in the C terminus of L-type CaV1.3 channels. The Journal of biological chemistry. 286 [PubMed]

Tang ZZ et al. (2004). Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit. The Journal of biological chemistry. 279 [PubMed]

Theunissen F, Miller JP. (1995). Temporal encoding in nervous systems: a rigorous definition. Journal of computational neuroscience. 2 [PubMed]

Turetsky BI, Bilker WB, Siegel SJ, Kohler CG, Gur RE. (2009). Profile of auditory information-processing deficits in schizophrenia. Psychiatry research. 165 [PubMed]

Turetsky BI et al. (2007). Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophrenia bulletin. 33 [PubMed]

Vanmolkot KR et al. (2007). The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online. Human mutation. 28 [PubMed]

Volkers L et al. (2011). Nav 1.1 dysfunction in genetic epilepsy with febrile seizures-plus or Dravet syndrome. The European journal of neuroscience. 34 [PubMed]

Whitaker WR et al. (2000). Distribution of voltage-gated sodium channel alpha-subunit and beta-subunit mRNAs in human hippocampal formation, cortex, and cerebellum. The Journal of comparative neurology. 422 [PubMed]

Wilson C. (2008). Up and down states. Scholarpedia journal. 3 [PubMed]

Yli-Harja O, Maki-Marttunen T, Nykter M, Kesseli J, Kauffman S. (2011). Of the complexity of boolean network state trajectories Eight International Workshop on Computational Systems Biology, WCSB 2011, June 6-8, Zurich, Switzerland. TICSP series.

Zhang Q et al. (2011). Expression and roles of Cav1.3 (a1D) L-type Ca²+ channel in atrioventricular node automaticity. Journal of molecular and cellular cardiology. 50 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.