Persistent synchronized bursting activity in cortical tissues (Golomb et al 2005)

The program simulates a one-dimensional model of a cortical tissue with excitatory and inhibitory populations.

Model Type: Realistic Network

Region(s) or Organism(s): Neocortex

Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Abstract Wang-Buzsaki neuron

Currents: I Na,p; I Na,t; I K; I K,leak; I M

Receptors: GabaA; AMPA; NMDA

Transmitters: Gaba; Glutamate

Model Concept(s): Bursting; Oscillations; Synchronization; Epilepsy

Simulation Environment: C or C++ program

Implementer(s): Golomb, David [golomb at bgu.ac.il]

References:

Golomb D, Shedmi A, Curtu R, Ermentrout GB. (2006). Persistent synchronized bursting activity in cortical tissues with low magnesium concentration: a modeling study. Journal of neurophysiology. 95 [PubMed]