Gottschalk A, Haney P. (2003). Computational aspects of anesthetic action in simple neural models. Anesthesiology. 98 [PubMed]

See more from authors: Gottschalk A · Haney P

References and models cited by this paper

Alkire MT. (1998). Quantitative EEG correlations with brain glucose metabolic rate during anesthesia in volunteers. Anesthesiology. 89 [PubMed]

Alkire MT, Haier RJ, Fallon JH. (2000). Toward a unified theory of narcosis: brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness. Consciousness and cognition. 9 [PubMed]

Alkire MT et al. (1999). Functional brain imaging during anesthesia in humans: effects of halothane on global and regional cerebral glucose metabolism. Anesthesiology. 90 [PubMed]

Antognini JF, Schwartz K. (1993). Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology. 79 [PubMed]

BACKMAN LE, LOEFSTROEM B, WIDEN L. (1964). ELECTRO-ENCEPHALOGRAPHY IN HALOTHANE ANAESTHESIA. Acta anaesthesiologica Scandinavica. 8 [PubMed]

Banks MI, Pearce RA. (1999). Dual actions of volatile anesthetics on GABA(A) IPSCs: dissociation of blocking and prolonging effects. Anesthesiology. 90 [PubMed]

Barker JL, Harrison NL, Lange GD, Owen DG. (1987). Potentiation of gamma-aminobutyric-acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones. The Journal of physiology. 386 [PubMed]

Birnir B, Tierney ML, Dalziel JE, Cox GB, Gage PW. (1997). A structural determinant of desensitization and allosteric regulation by pentobarbitone of the GABAA receptor. The Journal of membrane biology. 155 [PubMed]

Borges M, Antognini JF. (1994). Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia? Anesthesiology. 81 [PubMed]

Bower JM, Beeman D. (1998). The Book Of Genesis: Exploring Realistic Neural Models With The General Neural Simulation System.

Bowery NG et al. (1984). GABA receptor multiplicity. Visualization of different receptor types in the mammalian CNS. Neuropharmacology. 23 [PubMed]

Buzsáki G, Leung LW, Vanderwolf CH. (1983). Cellular bases of hippocampal EEG in the behaving rat. Brain research. 287 [PubMed]

Carlson B, Hales T, Olsen R. (1997). GABAA Receptors and Anesthesia. Anesthesia:Biologic Foundations..

Carnahan B, Luther HA, Wilkes JO. (1969). Applied Numerical Methods..

Clark DL, Hosick EC, Rosner BS. (1971). Neurophysiological effects of different anesthetics in unconscious man. Journal of applied physiology. 31 [PubMed]

Deschênes M, Paradis M, Roy JP, Steriade M. (1984). Electrophysiology of neurons of lateral thalamic nuclei in cat: resting properties and burst discharges. Journal of neurophysiology. 51 [PubMed]

Destexhe A, Bal T, McCormick DA, Sejnowski TJ. (1996). Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices. Journal of neurophysiology. 76 [PubMed]

Destexhe A, Contreras D, Steriade M, Sejnowski TJ, Huguenard JR. (1996). In vivo, in vitro, and computational analysis of dendritic calcium currents in thalamic reticular neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Destexhe A, Mainen ZF, Sejnowski TJ. (1994). Synthesis of models for excitable membranes, synaptic transmission and neuromodulation using a common kinetic formalism. Journal of computational neuroscience. 1 [PubMed]

Eckenhoff RG, Johansson JS. (1999). On the relevance of "clinically relevant concentrations" of inhaled anesthetics in in vitro experiments. Anesthesiology. 91 [PubMed]

Eger EI et al. (2001). Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms. Anesthesiology. 94 [PubMed]

Eger EI, Saidman LJ, Brandstater B. (1965). Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology. 26 [PubMed]

Eger EI, Stoelting RK, Longnecker DE. (1970). Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake. Anesthesiology. 33

Ehlers CL, Havstad J, Prichard D, Theiler J. (1998). Low doses of ethanol reduce evidence for nonlinear structure in brain activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Evans RH, Hill RG. (1978). GABA-mimetic action of etomidate. Experientia. 34 [PubMed]

Faulkner HJ, Traub RD, Whittington MA. (1998). Disruption of synchronous gamma oscillations in the rat hippocampal slice: a common mechanism of anaesthetic drug action. British journal of pharmacology. 125 [PubMed]

Faulkner HJ, Traub RD, Whittington MA. (1999). Anaesthetic/amnesic agents disrupt beta frequency oscillations associated with potentiation of excitatory synaptic potentials in the rat hippocampal slice. British journal of pharmacology. 128 [PubMed]

Franks NP, Lieb WR. (1994). Molecular and cellular mechanisms of general anaesthesia. Nature. 367 [PubMed]

Fujiwara N et al. (1988). Changes in spontaneous firing patterns of rat hippocampal neurones induced by volatile anaesthetics. The Journal of physiology. 402 [PubMed]

Galarreta M, Hestrin S. (1999). A network of fast-spiking cells in the neocortex connected by electrical synapses. Nature. 402 [PubMed]

Galarreta M, Hestrin S. (2001). Spike transmission and synchrony detection in networks of GABAergic interneurons. Science (New York, N.Y.). 292 [PubMed]

Golomb D, Wang XJ, Rinzel J. (1994). Synchronization properties of spindle oscillations in a thalamic reticular nucleus model. Journal of neurophysiology. 72 [PubMed]

Gottschalk A. (2001). Seeking an integrated model of anesthetic action. Anesthesiology. 95 [PubMed]

Guckenheimer J, Holmes P. (1983). Nonlinear Oscillations, Dynamical Systems, and Bifurcations of Vector Fields, 2nd edition..

HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]

Hales TG, Lambert JJ. (1991). The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. British journal of pharmacology. 104 [PubMed]

Haydon DA, Urban BW. (1983). The effects of some inhalation anaesthetics on the sodium current of the squid giant axon. The Journal of physiology. 341 [PubMed]

Haydon DA, Urban BW. (1986). The actions of some general anaesthetics on the potassium current of the squid giant axon. The Journal of physiology. 373 [PubMed]

Heinke W, Schwarzbauer C. (2001). Subanesthetic isoflurane affects task-induced brain activation in a highly specific manner: a functional magnetic resonance imaging study. Anesthesiology. 94 [PubMed]

Herrington J, Stern RC, Evers AS, Lingle CJ. (1991). Halothane inhibits two components of calcium current in clonal (GH3) pituitary cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 11 [PubMed]

Homanics GE et al. (1997). Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics. Molecular pharmacology. 51 [PubMed]

Jefferys JG, Traub RD, Whittington MA. (1996). Neuronal networks for induced '40 Hz' rhythms. Trends in neurosciences. 19 [PubMed]

Johansen JW, Sebel PS. (2000). Development and clinical application of electroencephalographic bispectrum monitoring. Anesthesiology. 93 [PubMed]

Jones MV, Harrison NL. (1993). Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons. Journal of neurophysiology. 70 [PubMed]

Kamatchi GL, Chan CK, Snutch T, Durieux ME, Lynch C. (1999). Volatile anesthetic inhibition of neuronal Ca channel currents expressed in Xenopus oocytes. Brain research. 831 [PubMed]

Levy WJ. (2001). Neurophysiologic brain monitoring: electroencephalography. Anesthesia and Neurosurgery,4th edition..

Llinás R, Ribary U, Contreras D, Pedroarena C. (1998). The neuronal basis for consciousness. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 353 [PubMed]

Lumer ED, Edelman GM, Tononi G. (1997). Neural dynamics in a model of the thalamocortical system. I. Layers, loops and the emergence of fast synchronous rhythms. Cerebral cortex (New York, N.Y. : 1991). 7 [PubMed]

Macdonald RL, Twyman RE, Rogers CJ, Weddle MG. (1988). Pentobarbital regulation of the kinetic properties of GABA receptor chloride channels. Advances in biochemical psychopharmacology. 45 [PubMed]

Marder E, Abbott LF, Turrigiano GG, Liu Z, Golowasch J. (1996). Memory from the dynamics of intrinsic membrane currents. Proceedings of the National Academy of Sciences of the United States of America. 93 [PubMed]

Maren S, Baudry M. (1995). Properties and mechanisms of long-term synaptic plasticity in the mammalian brain: relationships to learning and memory. Neurobiology of learning and memory. 63 [PubMed]

McCormick DA, Huguenard JR. (1992). A model of the electrophysiological properties of thalamocortical relay neurons. Journal of neurophysiology. 68 [PubMed]

McDowell TS, Pancrazio JJ, Barrett PQ, Lynch C. (1999). Volatile anesthetic sensitivity of T-type calcium currents in various cell types. Anesthesia and analgesia. 88 [PubMed]

Miao N, Nagao K, Lynch C. (1998). Thiopental and methohexital depress Ca2+ entry into and glutamate release from cultured neurons. Anesthesiology. 88 [PubMed]

Migliore M, Cook EP, Jaffe DB, Turner DA, Johnston D. (1995). Computer simulations of morphologically reconstructed CA3 hippocampal neurons. Journal of neurophysiology. 73 [PubMed]

Moller JT et al. (1998). Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. Lancet (London, England). 351 [PubMed]

Morris C, Lecar H. (1981). Voltage oscillations in the barnacle giant muscle fiber. Biophysical journal. 35 [PubMed]

Namba T et al. (2000). Inhibition of the human intermediate conductance Ca(2+)-activated K(+) channel, hIK1, by volatile anesthetics. European journal of pharmacology. 395 [PubMed]

Newman J. (1997). Putting the puzzle together. Part I: Towards a general theory of the neural correlates of consciousness. J Consciousness Stud. 4

Pancrazio JJ, Park WK, Lynch C. (1992). Effects of enflurane on the voltage-gated membrane currents of bovine adrenal chromaffin cells. Neuroscience letters. 146 [PubMed]

Pancrazio JJ, Park WK, Lynch C. (1993). Inhalational anesthetic actions on voltage-gated ion currents of bovine adrenal chromaffin cells. Molecular pharmacology. 43 [PubMed]

Patel AJ, Honoré E. (2001). Anesthetic-sensitive 2P domain K+ channels. Anesthesiology. 95 [PubMed]

Patel AJ et al. (1999). Inhalational anesthetics activate two-pore-domain background K+ channels. Nature neuroscience. 2 [PubMed]

Pearce RA. (1996). Volatile anaesthetic enhancement of paired-pulse depression investigated in the rat hippocampus in vitro. The Journal of physiology. 492 ( Pt 3) [PubMed]

Pichlmayr I, Lips U. (1980). [EEG effects of diazepam. Studies on 16 patients (author's transl)]. Der Anaesthesist. 29 [PubMed]

Pike FG et al. (2000). Distinct frequency preferences of different types of rat hippocampal neurones in response to oscillatory input currents. The Journal of physiology. 529 Pt 1 [PubMed]

Pinsky PF, Rinzel J. (1994). Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. Journal of computational neuroscience. 1 [PubMed]

Proctor WR, Mynlieff M, Dunwiddie TV. (1986). Facilitatory action of etomidate and pentobarbital on recurrent inhibition in rat hippocampal pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 6 [PubMed]

Quinlan JJ, Homanics GE, Firestone LL. (1998). Anesthesia sensitivity in mice that lack the beta3 subunit of the gamma-aminobutyric acid type A receptor. Anesthesiology. 88 [PubMed]

Raines DE, Claycomb RJ, Scheller M, Forman SA. (2001). Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels. Anesthesiology. 95 [PubMed]

Rampil IJ, Laster MJ. (1992). No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats. Anesthesiology. 77 [PubMed]

Rampil IJ et al. (1991). The electroencephalographic effects of desflurane in humans. Anesthesiology. 74 [PubMed]

Rinzel J, Ermentrout B. (1998). Analysis of neural excitability and oscillations. Methods In Neuronal Modeling 2nd Edition.

Rinzel J, Golomb D. (1994). Clustering in globally coupled inhibitory neurons Physica D. 72

Rinzel J, Pinsky PF. (1995). Erratum for Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci. 2

Roizen MF, Horrigan RW, Frazer BM. (1981). Anesthetic doses blocking adrenergic (stress) and cardiovascular responses to incision--MAC BAR. Anesthesiology. 54 [PubMed]

Saidman LJ, Lynch C, Yaksh TL, Zapol WM, Biebuyck JF. (1998). Anesthesia Biologic Foundations..

Schulz DW, Macdonald RL. (1981). Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions. Brain research. 209 [PubMed]

Segev I, Koch C. (1998). Methods In Neuronal Modeling.

Sherman SM. (2001). Tonic and burst firing: dual modes of thalamocortical relay. Trends in neurosciences. 24 [PubMed]

Singer W. (1999). Neuronal synchrony: a versatile code for the definition of relations? Neuron. 24 [PubMed]

Sirois JE, Lei Q, Talley EM, Lynch C, Bayliss DA. (2000). The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]

Steinmetz PN et al. (2000). Attention modulates synchronized neuronal firing in primate somatosensory cortex. Nature. 404 [PubMed]

Steriade M. (1993). Cellular substrates of brain rhythms. Electroencephalography: Basic Principles, Clinical Applications, and Related Fields, 3rd Edition..

Steriade M, Deschenes M. (1984). The thalamus as a neuronal oscillator. Brain research. 320 [PubMed]

Steyn-Ross ML, Steyn-Ross DA, Sleigh JW, Liley DT. (1999). Theoretical electroencephalogram stationary spectrum for a white-noise-driven cortex: evidence for a general anesthetic-induced phase transition. Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics. 60 [PubMed]

Study RE. (1994). Isoflurane inhibits multiple voltage-gated calcium currents in hippocampal pyramidal neurons. Anesthesiology. 81 [PubMed]

Study RE, Barker JL. (1981). Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons. Proceedings of the National Academy of Sciences of the United States of America. 78 [PubMed]

Swadlow HA, Gusev AG. (2001). The impact of 'bursting' thalamic impulses at a neocortical synapse. Nature neuroscience. 4 [PubMed]

Tas PW, Kress HG, Koschel K. (1989). Volatile anesthetics inhibit the ion flux through Ca2+-activated K+ channels of rat glioma C6 cells. Biochimica et biophysica acta. 983 [PubMed]

Traub RD, Jefferys JG, Miles R, Whittington MA, Tóth K. (1994). A branching dendritic model of a rodent CA3 pyramidal neurone. The Journal of physiology. 481 ( Pt 1) [PubMed]

Traub RD et al. (2001). Gap junctions between interneuron dendrites can enhance synchrony of gamma oscillations in distributed networks. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Traub RD, Wong RK, Miles R, Michelson H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology. 66 [PubMed]

Turrigiano G, LeMasson G, Marder E. (1995). Selective regulation of current densities underlies spontaneous changes in the activity of cultured neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 15 [PubMed]

Turrigiano GG, Leslie KR, Desai NS, Rutherford LC, Nelson SB. (1998). Activity-dependent scaling of quantal amplitude in neocortical neurons. Nature. 391 [PubMed]

Twyman RE, Macdonald RL. (1992). Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture. The Journal of physiology. 456 [PubMed]

Vaadia E et al. (1995). Dynamics of neuronal interactions in monkey cortex in relation to behavioural events. Nature. 373 [PubMed]

Veselis RA, Reinsel RA, Feshchenko VA. (2001). Drug-induced amnesia is a separate phenomenon from sedation: electrophysiologic evidence. Anesthesiology. 95 [PubMed]

Wang XJ, Buzsáki G. (1996). Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Wang XJ, Golomb D, Rinzel J. (1995). Emergent spindle oscillations and intermittent burst firing in a thalamic model: specific neuronal mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 92 [PubMed]

White JA, Chow CC, Ritt J, Soto-Treviño C, Kopell N. (1998). Synchronization and oscillatory dynamics in heterogeneous, mutually inhibited neurons. Journal of computational neuroscience. 5 [PubMed]

Whittington MA, Jefferys JG, Traub RD. (1996). Effects of intravenous anaesthetic agents on fast inhibitory oscillations in the rat hippocampus in vitro. British journal of pharmacology. 118 [PubMed]

Wolfram S. (1999). The Mathematica Book, 4th edition. .

Yakaitis RW, Blitt CD, Angiulo JP. (1977). End-tidal halothane concentration for endotracheal intubation. Anesthesiology. 47 [PubMed]

Yamakura T, Harris RA. (2000). Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison with isoflurane and ethanol. Anesthesiology. 93 [PubMed]

Zhu WJ, Vicini S. (1997). Neurosteroid prolongs GABAA channel deactivation by altering kinetics of desensitized states. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

de Jong RH, Eger EI. (1975). MAC expanded: AD50 and AD95 values of common inhalation anesthetics in man. Anesthesiology. 42 [PubMed]

de Sousa SL, Dickinson R, Lieb WR, Franks NP. (2000). Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon. Anesthesiology. 92 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.