Agrawal N, Hamam BN, Magistretti J, Alonso A, Ragsdale DS. (2001). Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons. Neuroscience. 102 [PubMed]
Baker MD, Bostock H. (1997). Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture. Journal of neurophysiology. 77 [PubMed]
Bennett BD, Callaway JC, Wilson CJ. (2000). Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 20 [PubMed]
Booth V, Rinzel J, Kiehn O. (1997). Compartmental model of vertebrate motoneurons for Ca2+-dependent spiking and plateau potentials under pharmacological treatment. Journal of neurophysiology. 78 [PubMed]
Butera RJ, Rinzel J, Smith JC. (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons. Journal of neurophysiology. 82 [PubMed]
Calvin WH. (1975). Generation of spike trains in CNS neurons. Brain research. 84 [PubMed]
Cao YJ, Dreixler JC, Couey JJ, Houamed KM. (2002). Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole. European journal of pharmacology. 449 [PubMed]
Carriedo SG, Yin HZ, Weiss JH. (1996). Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]
Crill WE. (1996). Persistent sodium current in mammalian central neurons. Annual review of physiology. 58 [PubMed]
Darbon P, Yvon C, Legrand JC, Streit J. (2004). INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons. The European journal of neuroscience. 20 [PubMed]
Del Negro CA, Morgado-Valle C, Feldman JL. (2002). Respiratory rhythm: an emergent network property? Neuron. 34 [PubMed]
Del Negro CA et al. (2005). Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Destexhe A. (1997). Conductance-based integrate-and-fire models. Neural computation. 9 [PubMed]
Do MT, Bean BP. (2003). Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation. Neuron. 39 [PubMed]
Fleidervish IA, Gutnick MJ. (1996). Kinetics of slow inactivation of persistent sodium current in layer V neurons of mouse neocortical slices. Journal of neurophysiology. 76 [PubMed]
Garraway SM, Hochman S. (2001). Modulatory actions of serotonin, norepinephrine, dopamine, and acetylcholine in spinal cord deep dorsal horn neurons. Journal of neurophysiology. 86 [PubMed]
Gasparini S, Migliore M, Magee JC. (2004). On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]
Grudt TJ, Perl ER. (2002). Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. The Journal of physiology. 540 [PubMed]
HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]
Hille B. (2001). Ion channels of excitable membranes (3rd Ed).
Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]
Hsiao CF, Del Negro CA, Trueblood PR, Chandler SH. (1998). Ionic basis for serotonin-induced bistable membrane properties in guinea pig trigeminal motoneurons. Journal of neurophysiology. 79 [PubMed]
Huang CS, Song JH, Nagata K, Yeh JZ, Narahashi T. (1997). Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons. The Journal of pharmacology and experimental therapeutics. 282 [PubMed]
Kay AR, Sugimori M, Llinás R. (1998). Kinetic and stochastic properties of a persistent sodium current in mature guinea pig cerebellar Purkinje cells. Journal of neurophysiology. 80 [PubMed]
Khaliq ZM, Gouwens NW, Raman IM. (2003). The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]
Kononenko NI, Shao LR, Dudek FE. (2004). Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons. Journal of neurophysiology. 91 [PubMed]
Kuo JJ et al. (2004). Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. Journal of neurophysiology. 91 [PubMed]
Kuo JJ, Siddique T, Fu R, Heckman CJ. (2005). Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice. The Journal of physiology. 563 [PubMed]
Lacomblez L et al. (1996). A confirmatory dose-ranging study of riluzole in ALS. ALS/Riluzole Study Group-II. Neurology. 47 [PubMed]
Larkum ME, Senn W, Lüscher HR. (2004). Top-down dendritic input increases the gain of layer 5 pyramidal neurons. Cerebral cortex (New York, N.Y. : 1991). 14 [PubMed]
Lee RH, Heckman CJ. (1999). Paradoxical effect of QX-314 on persistent inward currents and bistable behavior in spinal motoneurons in vivo. Journal of neurophysiology. 82 [PubMed]
Lee RH, Heckman CJ. (2001). Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing. Journal of neurophysiology. 85 [PubMed]
Li Y, Bennett DJ. (2003). Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats. Journal of neurophysiology. 90 [PubMed]
Li Y, Gorassini MA, Bennett DJ. (2004). Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats. Journal of neurophysiology. 91 [PubMed]
Lipowsky R, Gillessen T, Alzheimer C. (1996). Dendritic Na+ channels amplify EPSPs in hippocampal CA1 pyramidal cells. Journal of neurophysiology. 76 [PubMed]
Peña F, Parkis MA, Tryba AK, Ramirez JM. (2004). Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia. Neuron. 43 [PubMed]
Powers RK, Binder MD. (2001). Input-output functions of mammalian motoneurons. Reviews of physiology, biochemistry and pharmacology. 143 [PubMed]
Powers RK, Binder MD. (2003). Persistent sodium and calcium currents in rat hypoglossal motoneurons. Journal of neurophysiology. 89 [PubMed]
Prescott SA, De Koninck Y. (2002). Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat. The Journal of physiology. 539 [PubMed]
Prescott SA, De Koninck Y. (2005). Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Ptak K et al. (2005). Sodium currents in medullary neurons isolated from the pre-Bötzinger complex region. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]
Raman IM, Bean BP. (1997). Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]
Reboreda A, Sánchez E, Romero M, Lamas JA. (2003). Intrinsic spontaneous activity and subthreshold oscillations in neurones of the rat dorsal column nuclei in culture. The Journal of physiology. 551 [PubMed]
Rosen DR et al. (1993). Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 362 [PubMed]
Ruscheweyh R, Sandkühler J. (2002). Lamina-specific membrane and discharge properties of rat spinal dorsal horn neurones in vitro. The Journal of physiology. 541 [PubMed]
Rybak IA, Shevtsova NA, St-John WM, Paton JF, Pierrefiche O. (2003). Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studies. The European journal of neuroscience. 18 [PubMed]
Safronov BV, Vogel W. (1995). Single voltage-activated Na+ and K+ channels in the somata of rat motoneurones. The Journal of physiology. 487 [PubMed]
Schlue WR, Richter DW, Mauritz KH, Nacimiento AC. (1972). Accomodation and Na-inactivation in cat spinal motor neurons. Pflugers Archiv : European journal of physiology. 332 [PubMed]
Schwindt PC, Crill WE. (1995). Amplification of synaptic current by persistent sodium conductance in apical dendrite of neocortical neurons. Journal of neurophysiology. 74 [PubMed]
Song JH, Huang CS, Nagata K, Yeh JZ, Narahashi T. (1997). Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. The Journal of pharmacology and experimental therapeutics. 282 [PubMed]
Spadoni F et al. (2002). Lamotrigine derivatives and riluzole inhibit INa,P in cortical neurons. Neuroreport. 13 [PubMed]
Steriade M. (2001). Impact of network activities on neuronal properties in corticothalamic systems. Journal of neurophysiology. 86 [PubMed]
Stuart G, Sakmann B. (1995). Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons. Neuron. 15 [PubMed]
Stuart G, Spruston N, Sakmann B, Häusser M. (1997). Action potential initiation and backpropagation in neurons of the mammalian CNS. Trends in neurosciences. 20 [PubMed]
Swensen AM, Bean BP. (2003). Ionic mechanisms of burst firing in dissociated Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]
Szûcs P, Odeh F, Szokol K, Antal M. (2003). Neurons with distinctive firing patterns, morphology and distribution in laminae V-VII of the neonatal rat lumbar spinal cord. The European journal of neuroscience. 17 [PubMed]
Taddese A, Bean BP. (2002). Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons. Neuron. 33 [PubMed]
Theiss RD, Heckman CJ. (2005). Systematic variation in effects of serotonin and norepinephrine on repetitive firing properties of ventral horn neurons. Neuroscience. 134 [PubMed]
Turner RW, Meyers DE, Richardson TL, Barker JL. (1991). The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 11 [PubMed]
Urbani A, Belluzzi O. (2000). Riluzole inhibits the persistent sodium current in mammalian CNS neurons. The European journal of neuroscience. 12 [PubMed]
Uteshev V, Stevens DR, Haas HL. (1995). A persistent sodium current in acutely isolated histaminergic neurons from rat hypothalamus. Neuroscience. 66 [PubMed]
Wu N et al. (2005). Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability. Journal of neurophysiology. 93 [PubMed]
Zona C et al. (2003). Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis. Neurosci Lett. 351
Zona C, Siniscalchi A, Mercuri NB, Bernardi G. (1998). Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons. Neuroscience. 85 [PubMed]
Kovalsky Y, Amir R, Devor M. (2009). Simulation in sensory neurons reveals a key role for delayed Na+ current in subthreshold oscillations and ectopic discharge: implications for neuropathic pain. Journal of neurophysiology. 102 [PubMed]
Powers RK, Elbasiouny SM, Rymer WZ, Heckman CJ. (2012). Contribution of intrinsic properties and synaptic inputs to motoneuron discharge patterns: a simulation study. Journal of neurophysiology. 107 [PubMed]
Powers RK, Heckman CJ. (2015). Contribution of intrinsic motoneuron properties to discharge hysteresis and its estimation based on paired motor unit recordings: a simulation study. Journal of neurophysiology. 114 [PubMed]
Shapiro NP, Lee RH. (2007). Synaptic amplification versus bistability in motoneuron dendritic processing: a top-down modeling approach. Journal of neurophysiology. 97 [PubMed]
Yvon C, Czarnecki A, Streit J. (2007). Riluzole-induced oscillations in spinal networks. Journal of neurophysiology. 97 [PubMed]