Avian nucleus isthmi pars parvocellularis (Ipc) neurons are reciprocally connected with the tectal layer 10 (L10) neurons and respond with oscillatory bursts to visual stimulation. To elucidate mechanisms of oscillatory bursting in this network of regularly spiking neurons, we investigated an experimentally constrained model of coupled leaky integrate-and-fire neurons with spike-rate adaptation. The model reproduces the observed Ipc oscillatory bursting in response to simulated visual stimulation.
Model Type: Realistic Network
Receptors: AMPA
Transmitters: Acetylcholine; Glutamate
Model Concept(s): Bursting; Oscillations; Vision
Simulation Environment: C or C++ program
Implementer(s): Lai, Dihui [dlai at artsci.wustl.edu]
References:
Shao J, Lai D, Meyer U, Luksch H, Wessel R. (2009). Generating oscillatory bursts from a network of regular spiking neurons without inhibition. Journal of computational neuroscience. 27 [PubMed]