We present a unified model of the thalamus that is capable of independently generating multiple distinct oscillations (delta, spindle, alpha and gamma oscillations) under different levels of acetylcholine (ACh) and norepinephrine (NE) modulation corresponding to different physiological conditions (deep sleep, light sleep, relaxed wakefulness and attention). The model also shows that entrainment of thalamic oscillations is state-dependent.
Model Type: Realistic Network
Region(s) or Organism(s): Thalamus
Simulation Environment: C or C++ program
Implementer(s): Li, Guoshi [guoshi_li at med.unc.edu]