Disentangling astroglial physiology with a realistic cell model in silico (Savtchenko et al 2018)


Savtchenko LP et al. (2018). Disentangling astroglial physiology with a realistic cell model in silico. Nature communications. 9 [PubMed]

See more from authors: Savtchenko LP · Bard L · Jensen TP · Reynolds JP · Kraev I · Medvedev N · Stewart MG · Henneberger C · Rusakov DA

References and models cited by this paper

Anders S et al. (2014). Spatial properties of astrocyte gap junction coupling in the rat hippocampus. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 369 [PubMed]

Araque A et al. (2014). Gliotransmitters travel in time and space. Neuron. 81 [PubMed]

Bazargani N, Attwell D. (2016). Astrocyte calcium signaling: the third wave. Nature neuroscience. 19 [PubMed]

Bergles DE, Tzingounis AV, Jahr CE. (2002). Comparison of coupled and uncoupled currents during glutamate uptake by GLT-1 transporters. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Berridge MJ, Taylor CW. (1988). Inositol trisphosphate and calcium signaling. Cold Spring Harbor symposia on quantitative biology. 53 Pt 2 [PubMed]

Bushong EA, Martone ME, Jones YZ, Ellisman MH. (2002). Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Cao P, Donovan G, Falcke M, Sneyd J. (2013). A stochastic model of calcium puffs based on single-channel data. Biophysical journal. 105 [PubMed]

Chen KC, Nicholson C. (2000). Spatial buffering of potassium ions in brain extracellular space. Biophysical journal. 78 [PubMed]

Chen TW et al. (2013). Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature. 499 [PubMed]

Chvátal A, Anderová M, Kirchhoff F. (2007). Three-dimensional confocal morphometry - a new approach for studying dynamic changes in cell morphology in brain slices. Journal of anatomy. 210 [PubMed]

De Pittà M, Goldberg M, Volman V, Berry H, Ben-Jacob E. (2009). Glutamate regulation of calcium and IP3 oscillating and pulsating dynamics in astrocytes. Journal of biological physics. 35 [PubMed]

De Pittà M, Volman V, Berry H, Ben-Jacob E. (2011). A tale of two stories: astrocyte regulation of synaptic depression and facilitation. PLoS computational biology. 7 [PubMed]

Di Castro MA et al. (2011). Local Ca2+ detection and modulation of synaptic release by astrocytes. Nature neuroscience. 14 [PubMed]

Ding F et al. (2013). a1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice. Cell calcium. 54 [PubMed]

Djukic B, Casper KB, Philpot BD, Chin LS, McCarthy KD. (2007). Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Fink CC et al. (2000). An image-based model of calcium waves in differentiated neuroblastoma cells. Biophysical journal. 79 [PubMed]

Giaume C, Koulakoff A, Roux L, Holcman D, Rouach N. (2010). Astroglial networks: a step further in neuroglial and gliovascular interactions. Nature reviews. Neuroscience. 11 [PubMed]

Golowasch J et al. (2009). Membrane capacitance measurements revisited: dependence of capacitance value on measurement method in nonisopotential neurons. Journal of neurophysiology. 102 [PubMed]

Grosche A et al. (2013). Versatile and simple approach to determine astrocyte territories in mouse neocortex and hippocampus. PloS one. 8 [PubMed]

Grosche J et al. (1999). Microdomains for neuron-glia interaction: parallel fiber signaling to Bergmann glial cells. Nature neuroscience. 2 [PubMed]

Hama K, Arii T, Katayama E, Marton M, Ellisman MH. (2004). Tri-dimensional morphometric analysis of astrocytic processes with high voltage electron microscopy of thick Golgi preparations. Journal of neurocytology. 33 [PubMed]

Haustein MD et al. (2014). Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82 [PubMed]

Henneberger C, Papouin T, Oliet SH, Rusakov DA. (2010). Long-term potentiation depends on release of D-serine from astrocytes. Nature. 463 [PubMed]

Hernjak N et al. (2005). Modeling and analysis of calcium signaling events leading to long-term depression in cerebellar Purkinje cells. Biophysical journal. 89 [PubMed]

Hines ML, Carnevale NT. (2001). NEURON: a tool for neuroscientists. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 7 [PubMed]

Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM. (2004). ModelDB: A Database to Support Computational Neuroscience. Journal of computational neuroscience. 17 [PubMed]

Höfer T, Venance L, Giaume C. (2002). Control and plasticity of intercellular calcium waves in astrocytes: a modeling approach. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Khakh BS, Sofroniew MV. (2015). Diversity of astrocyte functions and phenotypes in neural circuits. Nature neuroscience. 18 [PubMed]

Kofuji P, Newman EA. (2004). Potassium buffering in the central nervous system. Neuroscience. 129 [PubMed]

Korogod N, Petersen CC, Knott GW. (2015). Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation. eLife. 4 [PubMed]

Lehre KP, Danbolt NC. (1998). The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Lehre KP, Rusakov DA. (2002). Asymmetry of glia near central synapses favors presynaptically directed glutamate escape. Biophysical journal. 83 [PubMed]

MacVicar BA, Thompson RJ. (2010). Non-junction functions of pannexin-1 channels. Trends in neurosciences. 33 [PubMed]

Manninen T, Havela R, Linne ML. (2017). Reproducibility and Comparability of Computational Models for Astrocyte Calcium Excitability. Frontiers in neuroinformatics. 11 [PubMed]

Medvedev N et al. (2014). Glia selectively approach synapses on thin dendritic spines. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 369 [PubMed]

Nedergaard M. (1994). Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science (New York, N.Y.). 263 [PubMed]

Newman EA, Frambach DA, Odette LL. (1984). Control of extracellular potassium levels by retinal glial cell K+ siphoning. Science (New York, N.Y.). 225 [PubMed]

Ogata K, Kosaka T. (2002). Structural and quantitative analysis of astrocytes in the mouse hippocampus. Neuroscience. 113 [PubMed]

Oschmann F, Berry H, Obermayer K, Lenk K. (2018). From in silico astrocyte cell models to neuron-astrocyte network models: A review. Brain research bulletin. 136 [PubMed]

Panatier A et al. (2011). Astrocytes are endogenous regulators of basal transmission at central synapses. Cell. 146 [PubMed]

Parpura V et al. (1994). Glutamate-mediated astrocyte-neuron signalling. Nature. 369 [PubMed]

Patrushev I, Gavrilov N, Turlapov V, Semyanov A. (2013). Subcellular location of astrocytic calcium stores favors extrasynaptic neuron-astrocyte communication. Cell calcium. 54 [PubMed]

Ransom BR, Carlini WG. (1986). Astrocytes: Biochemistry, Physiology, and Pharmacology of Astrocytes.

Reeves AM, Shigetomi E, Khakh BS. (2011). Bulk loading of calcium indicator dyes to study astrocyte physiology: key limitations and improvements using morphological maps. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Ross WN. (2012). Understanding calcium waves and sparks in central neurons. Nature reviews. Neuroscience. 13 [PubMed]

Rungta RL et al. (2016). Ca2+ transients in astrocyte fine processes occur via Ca2+ influx in the adult mouse hippocampus. Glia. 64 [PubMed]

Rusakov DA. (2015). Disentangling calcium-driven astrocyte physiology. Nature reviews. Neuroscience. 16 [PubMed]

Rusakov DA, Bard L, Stewart MG, Henneberger C. (2014). Diversity of astroglial functions alludes to subcellular specialisation. Trends in neurosciences. 37 [PubMed]

Rusakov DA, Harrison E, Stewart MG. (1998). Synapses in hippocampus occupy only 1-2% of cell membranes and are spaced less than half-micron apart: a quantitative ultrastructural analysis with discussion of physiological implications. Neuropharmacology. 37 [PubMed]

Savtchenko LP, Rusakov DA. (2014). Regulation of rhythm genesis by volume-limited, astroglia-like signals in neural networks. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 369 [PubMed]

Savtchenko LP, Sylantyev S, Rusakov DA. (2013). Central synapses release a resource-efficient amount of glutamate. Nature neuroscience. 16 [PubMed]

Scemes E, Giaume C. (2006). Astrocyte calcium waves: what they are and what they do. Glia. 54 [PubMed]

Schaff J, Fink CC, Slepchenko B, Carson JH, Loew LM. (1997). A general computational framework for modeling cellular structure and function. Biophysical journal. 73 [PubMed]

Seifert G et al. (2009). Analysis of astroglial K+ channel expression in the developing hippocampus reveals a predominant role of the Kir4.1 subunit. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 [PubMed]

Shigetomi E et al. (2013). Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. The Journal of general physiology. 141 [PubMed]

Sibille J, Dao Duc K, Holcman D, Rouach N. (2015). The neuroglial potassium cycle during neurotransmission: role of Kir4.1 channels. PLoS computational biology. 11 [PubMed]

Smith IF, Wiltgen SM, Shuai J, Parker I. (2009). Ca(2+) puffs originate from preestablished stable clusters of inositol trisphosphate receptors. Science signaling. 2 [PubMed]

Srinivasan R et al. (2015). Ca(2+) signaling in astrocytes from Ip3r2(-/-) mice in brain slices and during startle responses in vivo. Nature neuroscience. 18 [PubMed]

Sylantyev S et al. (2008). Electric fields due to synaptic currents sharpen excitatory transmission. Science (New York, N.Y.). 319 [PubMed]

Taufiq-Ur-Rahman, Skupin A, Falcke M, Taylor CW. (2009). Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+. Nature. 458 [PubMed]

Thurley K et al. (2011). Timescales of IP(3)-evoked Ca(2+) spikes emerge from Ca(2+) puffs only at the cellular level. Biophysical journal. 101 [PubMed]

Ullah G, Jung P, Cornell-Bell AH. (2006). Anti-phase calcium oscillations in astrocytes via inositol (1, 4, 5)-trisphosphate regeneration. Cell calcium. 39 [PubMed]

Ventura R, Harris KM. (1999). Three-dimensional relationships between hippocampal synapses and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Verkhratsky A, Kettenmann H. (1996). Calcium signalling in glial cells. Trends in neurosciences. 19 [PubMed]

Viola GG et al. (2009). Morphological changes in hippocampal astrocytes induced by environmental enrichment in mice. Brain research. 1274 [PubMed]

Volterra A, Liaudet N, Savtchouk I. (2014). Astrocyte Ca²? signalling: an unexpected complexity. Nature reviews. Neuroscience. 15 [PubMed]

Wallach G et al. (2014). Glutamate mediated astrocytic filtering of neuronal activity. PLoS computational biology. 10 [PubMed]

Wallraff A et al. (2006). The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Wang Z, Tymianski M, Jones OT, Nedergaard M. (1997). Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17 [PubMed]

Witcher MR et al. (2010). Three-dimensional relationships between perisynaptic astroglia and human hippocampal synapses. Glia. 58 [PubMed]

Zhang Z et al. (2007). Transport direction determines the kinetics of substrate transport by the glutamate transporter EAAC1. Proceedings of the National Academy of Sciences of the United States of America. 104 [PubMed]

Zheng K et al. (2015). Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca(2+) in Neurons and Astroglia. Neuron. 88 [PubMed]

Zheng K et al. (2017). Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging. Scientific reports. 7 [PubMed]

Zheng K, Scimemi A, Rusakov DA. (2008). Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns. Biophysical journal. 95 [PubMed]

References and models that cite this paper

Denizot A, Arizono M, Nägerl UV, Soula H, Berry H. (2019). Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity. PLoS computational biology. 15 [PubMed]

Manninen T, Saudargiene A, Linne ML. (2020). Astrocyte-mediated spike-timing-dependent long-term depression modulates synaptic properties in the developing cortex. PLoS computational biology. 16 [PubMed]

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