Mechanisms of extraneuronal space shrinkage (Ostby et al 2009)


Østby I et al. (2009). Astrocytic mechanisms explaining neural-activity-induced shrinkage of extraneuronal space. PLoS computational biology. 5 [PubMed]

See more from authors: Østby I · Øyehaug L · Einevoll GT · Nagelhus EA · Plahte E · Zeuthen T · Lloyd CM · Ottersen OP · Omholt SW

References and models cited by this paper

Aitken PG et al. (1998). Volume changes induced by osmotic stress in freshly isolated rat hippocampal neurons. Pflugers Archiv : European journal of physiology. 436 [PubMed]

Amiry-Moghaddam M, Frydenlund DS, Ottersen OP. (2004). Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport. Neuroscience. 129 [PubMed]

Amiry-Moghaddam M, Ottersen OP. (2003). The molecular basis of water transport in the brain. Nature reviews. Neuroscience. 4 [PubMed]

Anderson AW et al. (2000). Effects of cell volume fraction changes on apparent diffusion in human cells. Magnetic resonance imaging. 18 [PubMed]

Andrew RD, Labron MW, Boehnke SE, Carnduff L, Kirov SA. (2007). Physiological evidence that pyramidal neurons lack functional water channels. Cerebral cortex (New York, N.Y. : 1991). 17 [PubMed]

Ballanyi K, Grafe P, ten Bruggencate G. (1987). Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. The Journal of physiology. 382 [PubMed]

Beck J, Lenart B, Kintner DB, Sun D. (2003). Na-K-Cl cotransporter contributes to glutamate-mediated excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Boussouf A, Lambert RC, Gaillard S. (1997). Voltage-dependent Na(+)-HCO3- cotransporter and Na+/H+ exchanger are involved in intracellular pH regulation of cultured mature rat cerebellar oligodendrocytes. Glia. 19 [PubMed]

Butt AM, Kalsi A. (2006). Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for Kir4.1 in glial functions. Journal of cellular and molecular medicine. 10 [PubMed]

Cajal SR. (1909). Histologie du Systeme Nerveux de l'homme et des Vertebres. Paris: Meloine.

Casanova MF, Stevens JR, Brown R, Royston C, Bruton C. (2002). Disentangling the pathology of schizophrenia and paraphrenia. Acta neuropathologica. 103 [PubMed]

Chan WY, Kohsaka S, Rezaie P. (2007). The origin and cell lineage of microglia: new concepts. Brain research reviews. 53 [PubMed]

Chen KC, Nicholson C. (2000). Spatial buffering of potassium ions in brain extracellular space. Biophysical journal. 78 [PubMed]

Connors NC, Kofuji P. (2006). Potassium channel Kir4.1 macromolecular complex in retinal glial cells. Glia. 53 [PubMed]

D'Ambrosio R, Gordon DS, Winn HR. (2002). Differential role of KIR channel and Na(+)/K(+)-pump in the regulation of extracellular K(+) in rat hippocampus. Journal of neurophysiology. 87 [PubMed]

D'Ambrosio R, Maris DO, Grady MS, Winn HR, Janigro D. (1999). Impaired K(+) homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

D'Ambrosio R, Wenzel J, Schwartzkroin PA, McKhann GM, Janigro D. (1998). Functional specialization and topographic segregation of hippocampal astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18 [PubMed]

Deitmer JW, Szatkowski M. (1990). Membrane potential dependence of intracellular pH regulation by identified glial cells in the leech central nervous system. The Journal of physiology. 421 [PubMed]

Dietzel I, Heinemann U. (1986). Dynamic variations of the brain cell microenvironment in relation to neuronal hyperactivity. Annals of the New York Academy of Sciences. 481 [PubMed]

Dietzel I, Heinemann U, Hofmeier G, Lux HD. (1982). Stimulus-induced changes in extracellular Na+ and Cl- concentration in relation to changes in the size of the extracellular space. Experimental brain research. 46 [PubMed]

Dietzel I, Heinemann U, Lux HD. (1989). Relations between slow extracellular potential changes, glial potassium buffering, and electrolyte and cellular volume changes during neuronal hyperactivity in cat brain. Glia. 2 [PubMed]

Djukic B, Casper KB, Philpot BD, Chin LS, McCarthy KD. (2007). Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Duquette PP, Bissonnette P, Lapointe JY. (2001). Local osmotic gradients drive the water flux associated with Na(+)/glucose cotransport. Proceedings of the National Academy of Sciences of the United States of America. 98 [PubMed]

Gagnon KB, Adragna NC, Fyffe RE, Lauf PK. (2007). Characterization of glial cell K-Cl cotransport. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 20 [PubMed]

Gardner-Medwin AR. (1983). Analysis of potassium dynamics in mammalian brain tissue. The Journal of physiology. 335 [PubMed]

Hama K, Arii T, Katayama E, Marton M, Ellisman MH. (2004). Tri-dimensional morphometric analysis of astrocytic processes with high voltage electron microscopy of thick Golgi preparations. Journal of neurocytology. 33 [PubMed]

Hamann S, Herrera-Perez JJ, Bundgaard M, Alvarez-Leefmans FJ, Zeuthen T. (2005). Water permeability of Na+-K+-2Cl- cotransporters in mammalian epithelial cells. The Journal of physiology. 568 [PubMed]

Holthoff K, Witte OW. (1996). Intrinsic optical signals in rat neocortical slices measured with near-infrared dark-field microscopy reveal changes in extracellular space. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Hunter P, Robbins P, Noble D. (2002). The IUPS human Physiome Project. Pflugers Archiv : European journal of physiology. 445 [PubMed]

Ito U et al. (2006). Restitution of ischemic injuries in penumbra of cerebral cortex after temporary ischemia. Acta neurochirurgica. Supplement. 96 [PubMed]

KEYNES RD. (1951). The ionic movements during nervous activity. The Journal of physiology. 114 [PubMed]

Lauf PK, Adragna NC. (2000). K-Cl cotransport: properties and molecular mechanism. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 10 [PubMed]

Lloyd CM, Halstead MD, Nielsen PF. (2004). CellML: its future, present and past. Progress in biophysics and molecular biology. 85 [PubMed]

Luo CH, Rudy Y. (1994). A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circulation research. 74 [PubMed]

Lux HD, Heinemann U, Dietzel I. (1986). Ionic changes and alterations in the size of the extracellular space during epileptic activity. Advances in neurology. 44 [PubMed]

Lux HD, Neher E. (1973). The equilibration time course of (K + ) 0 in cat cortex. Experimental brain research. 17 [PubMed]

MacAulay N, Hamann S, Zeuthen T. (2004). Water transport in the brain: role of cotransporters. Neuroscience. 129 [PubMed]

MacVicar BA, Feighan D, Brown A, Ransom B. (2002). Intrinsic optical signals in the rat optic nerve: role for K(+) uptake via NKCC1 and swelling of astrocytes. Glia. 37 [PubMed]

Nagelhus EA et al. (1999). Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. Glia. 26 [PubMed]

Nagelhus EA, Mathiisen TM, Ottersen OP. (2004). Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1. Neuroscience. 129 [PubMed]

Nedergaard M, Ransom B, Goldman SA. (2003). New roles for astrocytes: redefining the functional architecture of the brain. Trends in neurosciences. 26 [PubMed]

Newman EA. (1991). Sodium-bicarbonate cotransport in retinal Müller (glial) cells of the salamander. The Journal of neuroscience : the official journal of the Society for Neuroscience. 11 [PubMed]

Newman EA. (1993). Inward-rectifying potassium channels in retinal glial (Müller) cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 13 [PubMed]

Newman EA. (1996). Acid efflux from retinal glial cells generated by sodium bicarbonate cotransport. The Journal of neuroscience : the official journal of the Society for Neuroscience. 16 [PubMed]

Nicchia GP et al. (2004). The role of aquaporin-4 in the blood-brain barrier development and integrity: studies in animal and cell culture models. Neuroscience. 129 [PubMed]

Nilius B, Eggermont J, Voets T, Droogmans G. (1996). Volume-activated Cl- channels. General pharmacology. 27 [PubMed]

O'Donnell ME, Lam TI, Tran LQ, Foroutan S, Anderson SE. (2006). Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 26 [PubMed]

Orkand RK, Nicholls JG, Kuffler SW. (1966). Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. Journal of neurophysiology. 29 [PubMed]

Pangrsic T, Potokar M, Haydon PG, Zorec R, Kreft M. (2006). Astrocyte swelling leads to membrane unfolding, not membrane insertion. Journal of neurochemistry. 99 [PubMed]

Pellerin L. (2005). How astrocytes feed hungry neurons. Molecular neurobiology. 32 [PubMed]

Ransom BR, Kettenmann H. (2005). Neuroglia. New York: Oxford University Press.

Ransom BR, Yamate CL, Connors BW. (1985). Activity-dependent shrinkage of extracellular space in rat optic nerve: a developmental study. The Journal of neuroscience : the official journal of the Society for Neuroscience. 5 [PubMed]

Rose CR, Kovalchuk Y, Eilers J, Konnerth A. (1999). Two-photon Na+ imaging in spines and fine dendrites of central neurons. Pflugers Archiv : European journal of physiology. 439 [PubMed]

Rose CR, Ransom BR. (1996). Intracellular sodium homeostasis in rat hippocampal astrocytes. The Journal of physiology. 491 ( Pt 2) [PubMed]

Ruiz-Ederra J, Zhang H, Verkman AS. (2007). Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Müller cells. The Journal of biological chemistry. 282 [PubMed]

Simard M, Nedergaard M. (2004). The neurobiology of glia in the context of water and ion homeostasis. Neuroscience. 129 [PubMed]

Sipilä ST, Schuchmann S, Voipio J, Yamada J, Kaila K. (2006). The cation-chloride cotransporter NKCC1 promotes sharp waves in the neonatal rat hippocampus. The Journal of physiology. 573 [PubMed]

Somjen GG. (2004). Ions in the brain: Normal function, seizures and stroke.

Su G, Kintner DB, Flagella M, Shull GE, Sun D. (2002). Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release. American journal of physiology. Cell physiology. 282 [PubMed]

Su G, Kintner DB, Sun D. (2002). Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes. American journal of physiology. Cell physiology. 282 [PubMed]

Syková E, Vargová L, Kubinová S, Jendelová P, Chvátal A. (2003). The relationship between changes in intrinsic optical signals and cell swelling in rat spinal cord slices. NeuroImage. 18 [PubMed]

Walz W. (1991). Accumulation of intracellular bicarbonate accounts for the missing anion during potassium-evoked swelling of cortical type-1-like astrocytes. Annals of the New York Academy of Sciences. 633 [PubMed]

Walz W, Hertz L. (1983). Intracellular ion changes of astrocytes in response to extracellular potassium. Journal of neuroscience research. 10 [PubMed]

Walz W, Hinks EC. (1985). Carrier-mediated KCl accumulation accompanied by water movements is involved in the control of physiological K+ levels by astrocytes. Brain research. 343 [PubMed]

Walz W, Hinks EC. (1986). A transmembrane sodium cycle in astrocytes. Brain research. 368 [PubMed]

Zagami CJ, O'Shea RD, Lau CL, Cheema SS, Beart PM. (2005). Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype. Neurotoxicity research. 7 [PubMed]

Zeuthen T, MacAulay N. (2002). Cotransporters as molecular water pumps. International review of cytology. 215 [PubMed]

References and models that cite this paper

Dormanns K, Brown RG, David T. (2016). The role of nitric oxide in neurovascular coupling. Journal of theoretical biology. 394 [PubMed]

Dormanns K, van Disseldorp EM, Brown RG, David T. (2015). Neurovascular coupling and the influence of luminal agonists via the endothelium. Journal of theoretical biology. 364 [PubMed]

Farr H, David T. (2011). Models of neurovascular coupling via potassium and EET signalling. Journal of theoretical biology. 286 [PubMed]

Halnes G, Ostby I, Pettersen KH, Omholt SW, Einevoll GT. (2013). Electrodiffusive model for astrocytic and neuronal ion concentration dynamics. PLoS computational biology. 9 [PubMed]

Hübel N, Hosseini-Zare MS, Žiburkus J, Ullah G. (2017). The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization. PLoS computational biology. 13 [PubMed]

Hübel N, Ullah G. (2016). Anions Govern Cell Volume: A Case Study of Relative Astrocytic and Neuronal Swelling in Spreading Depolarization. PloS one. 11 [PubMed]

Mathias EJ, Plank MJ, David T. (2017). A model of neurovascular coupling and the BOLD response: PART I. Computer methods in biomechanics and biomedical engineering. 20 [PubMed]

Sætra MJ, Einevoll GT, Halnes G. (2021). An electrodiffusive neuron-extracellular-glia model for exploring the genesis of slow potentials in the brain PLoS computational biology. 17 [PubMed]

Sætra MJ, Ellingsrud AJ, Rognes ME. (2023). Neural activity induces strongly coupled electro-chemo-mechanical interactions and fluid flow in astrocyte networks and extracellular space-A computational study. PLoS computational biology. 19 [PubMed]

Sætra MJ, Ellingsrud AJ, Rognes ME. (2023). Neural activity induces strongly coupled electro-chemo-mechanical interactions and fluid flow in astrocyte networks and extracellular space-A computational study. PLoS computational biology. 19 [PubMed]

Øyehaug L, Østby I, Lloyd CM, Omholt SW, Einevoll GT. (2012). Dependence of spontaneous neuronal firing and depolarisation block on astroglial membrane transport mechanisms. Journal of computational neuroscience. 32 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.