ModelDB: Models that contain Chemesis

Simulation Environment: Chemesis

Differences between type A and B photoreceptors (Blackwell 2006)
Paired turbulence and light effect on calcium increase in Hermissenda (Blackwell 2004)

http://krasnow1.gmu.edu/CENlab/software.html
Understanding the effect of neuromodulators requires modeling the dynamics of second messenger pathways and their effects on channel properties. Chemesis is software for modeling enzyme reactions, stoichiometric reactions, diffusion, and ligand gating of channels and is used in conjunction with GENESIS, the software program for neuronal modeling.

Top authors for Chemesis:

Blackwell KT (2)

Top concepts studied with Chemesis:

Invertebrate (2)
Activity Patterns (1)
Temporal Pattern Generation (1)
Signaling pathways (1)
Calcium dynamics (1)

Top neurons studied with Chemesis:

Hermissenda photoreceptor Type B (2)
Hermissenda photoreceptor Type A (1)

Top currents studied with Chemesis:

I A (2)
I h (2)
I K,Ca (2)
I Calcium (2)
I T low threshold (1)
I K (1)
I K,leak (1)
I Sodium (1)
I Potassium (1)

Top references cited by these models:

Bower JM, Beeman D. (1998). The Book Of Genesis: Exploring Realistic Neural Models With The General Neural Simulation System. (2)
Farley J, Alkon DL. (1982). Associative neural and behavioral change in Hermissenda: consequences of nervous system orientation for light and pairing specificity. Journal of neurophysiology. 48 (2)
Fost JW, Clark GA. (1996). Modeling Hermissenda: I. Differential contributions of IA and IC to type-B cell plasticity. Journal of computational neuroscience. 3 (2)
Frysztak RJ, Crow T. (1994). Enhancement of type B and A photoreceptor inhibitory synaptic connections in conditioned Hermissenda. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14 (2)
Ito E, Oka K, Collin C, Schreurs BG, Sakakibara M, Alkon DL. (1994). Intracellular calcium signals are enhanced for days after Pavlovian conditioning. Journal of neurochemistry. 62 (2)