Adachi R, Yamada R, Kuba H. (2015). Plasticity of the axonal trigger zone. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 21 [PubMed]

Almog M, Korngreen A. (2016). Is realistic neuronal modeling realistic? Journal of neurophysiology. 116 [PubMed]

Baranauskas G, David Y, Fleidervish IA. (2013). Spatial mismatch between the Na+ flux and spike initiation in axon initial segment. Proceedings of the National Academy of Sciences of the United States of America. 110 [PubMed]

Beaulieu-Laroche L et al. (2018). Enhanced Dendritic Compartmentalization in Human Cortical Neurons. Cell. 175 [PubMed]

Ben-Shalom R et al. (2017). Opposing Effects on NaV1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures. Biological psychiatry. 82 [PubMed]

• Pyramidal neurons with mutated SCN2A gene (Nav1.2) (Ben-Shalom et al 2017) [Model]

Boucher PA, Joós B, Morris CE. (2012). Coupled left-shift of Nav channels: modeling the Na?-loading and dysfunctional excitability of damaged axons. Journal of computational neuroscience. 33 [PubMed]

• Nodes of Ranvier with left-shifted Nav channels (Boucher et al. 2012) [Model]

Brette R. (2013). Sharpness of spike initiation in neurons explained by compartmentalization. PLoS computational biology. 9 [PubMed]

• Sharpness of spike initiation in neurons explained by compartmentalization (Brette 2013) [Model]

Debanne D, Campanac E, Bialowas A, Carlier E, Alcaraz G. (2011). Axon physiology. Physiological reviews. 91 [PubMed]

Doiron B, Longtin A, Turner RW, Maler L. (2001). Model of gamma frequency burst discharge generated by conditional backpropagation. Journal of neurophysiology. 86 [PubMed]

Feldman DE. (2012). The spike-timing dependence of plasticity. Neuron. 75 [PubMed]

Fletcher LN, Williams SR. (2019). Neocortical Topology Governs the Dendritic Integrative Capacity of Layer 5 Pyramidal Neurons. Neuron. 101 [PubMed]

Gulledge AT, Bravo JJ. (2016). Neuron Morphology Influences Axon Initial Segment Plasticity. eNeuro. 3 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]

• Squid axon (Hodgkin, Huxley 1952) (NEURON) [Model]
• Squid axon (Hodgkin, Huxley 1952) (SNNAP) [Model]
• Squid axon (Hodgkin, Huxley 1952) (LabAXON) [Model]
• Squid axon (Hodgkin, Huxley 1952) (SBML, XPP, other) [Model]
• Squid axon (Hodgkin, Huxley 1952) used in (Chen et al 2010) (R language) [Model]

Hay E, Hill S, Schürmann F, Markram H, Segev I. (2011). Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties. PLoS computational biology. 7 [PubMed]

• L5b PC model constrained for BAC firing and perisomatic current step firing (Hay et al., 2011) [Model]
• Layer V pyramidal cell model with reduced morphology (Mäki-Marttunen et al 2018) [Model]
• Cortical Layer 5b pyr. cell with [Na+]i mechanisms, from Hay et al 2011 (Zylbertal et al 2017) [Model]

Hu W et al. (2009). Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation. Nature neuroscience. 12 [PubMed]

• Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009) [Model]

Höfflin F et al. (2017). Heterogeneity of the Axon Initial Segment in Interneurons and Pyramidal Cells of Rodent Visual Cortex. Frontiers in cellular neuroscience. 11 [PubMed]

Joos B, Barlow BM, Morris CE. (2018). Calculating the Consequences of Left-Shifted Nav Channel Activity in Sick Excitable Cells. Handbook of experimental pharmacology. 246 [PubMed]

• Calculating the consequences of left-shifted Nav channel activity in sick cells (Joos et al 2018) [Model]

Katz E et al. (2018). Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. 115 [PubMed]

Kole MH et al. (2008). Action potential generation requires a high sodium channel density in the axon initial segment. Nature neuroscience. 11 [PubMed]

• Na+ channel dependence of AP initiation in cortical pyramidal neuron (Kole et al. 2008) [Model]

Kole MH, Stuart GJ. (2012). Signal processing in the axon initial segment. Neuron. 73 [PubMed]

Larkum ME, Kaiser KM, Sakmann B. (1999). Calcium electrogenesis in distal apical dendrites of layer 5 pyramidal cells at a critical frequency of back-propagating action potentials. Proceedings of the National Academy of Sciences of the United States of America. 96 [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron. 15 [PubMed]

• Spike Initiation in Neocortical Pyramidal Neurons (Mainen et al 1995) [Model]

Mainen ZF, Sejnowski TJ. (1996). Influence of dendritic structure on firing pattern in model neocortical neurons. Nature. 382 [PubMed]

• Influence of dendritic structure on neocortical neuron firing patterns (Mainen and Sejnowski 1996) [Model]

McDougal RA, Hines ML, Lytton WW. (2013). Reaction-diffusion in the NEURON simulator. Frontiers in neuroinformatics. 7 [PubMed]

• Reaction-diffusion in the NEURON simulator (McDougal et al 2013) [Model]

Michalikova M, Remme MW, Kempter R. (2017). Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma. PLoS computational biology. 13 [PubMed]

• Spikelet generation and AP initiation in a L5 neocortical pyr neuron (Michalikova et al. 2017) Fig 1 [Model]
• Spikelet generation and AP initiation in a simplified pyr neuron (Michalikova et al. 2017) Fig 3 [Model]

Petersen AV, Cotel F, Perrier JF. (2017). Plasticity of the Axon Initial Segment: Fast and Slow Processes with Multiple Functional Roles. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 23 [PubMed]

Regehr WG, Carey MR, Best AR. (2009). Activity-dependent regulation of synapses by retrograde messengers. Neuron. 63 [PubMed]

Rush AM, Dib-Hajj SD, Waxman SG. (2005). Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones. The Journal of physiology. 564 [PubMed]

Shu Y, Duque A, Yu Y, Haider B, McCormick DA. (2007). Properties of action-potential initiation in neocortical pyramidal cells: evidence from whole cell axon recordings. Journal of neurophysiology. 97 [PubMed]

• Intracortical synaptic potential modulation by presynaptic somatic potential (Shu et al. 2006, 2007) [Model]

Spratt PWE et al. (2021). Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells Cell reports. 36 [PubMed]

• Hyperexcitability from Nav1.2 channel loss in neocortical pyramidal cells (Spratt et al 2021) [Model]

Spratt PWE et al. (2019). The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex. Neuron. 103 [PubMed]

Tian C, Wang K, Ke W, Guo H, Shu Y. (2014). Molecular identity of axonal sodium channels in human cortical pyramidal cells. Frontiers in cellular neuroscience. 8 [PubMed]

Wang JA et al. (2009). Membrane trauma and Na+ leak from Nav1.6 channels. American journal of physiology. Cell physiology. 297 [PubMed]

Yin L et al. (2017). Selective Modulation of Axonal Sodium Channel Subtypes by 5-HT1A Receptor in Cortical Pyramidal Neuron. Cerebral cortex (New York, N.Y. : 1991). 27 [PubMed]

Zhu JJ. (2000). Maturation of layer 5 neocortical pyramidal neurons: amplifying salient layer 1 and layer 4 inputs by Ca2+ action potentials in adult rat tuft dendrites. The Journal of physiology. 526 Pt 3 [PubMed]