Wittman S, Abdala AP, Rubin JE. (2019). Reduced computational modelling of Kölliker-Fuse contributions to breathing patterns in Rett syndrome. The Journal of physiology. 597 [PubMed]

See more from authors: Wittman S · Abdala AP · Rubin JE

References and models cited by this paper

Anderson TM et al. (2016). A novel excitatory network for the control of breathing. Nature. 536 [PubMed]

Ausborn J et al. (2018). Organization of the core respiratory network: Insights from optogenetic and modeling studies. PLoS computational biology. 14 [PubMed]

Ausborn J, Snyder AC, Shevtsova NA, Rybak IA, Rubin JE. (2018). State-dependent rhythmogenesis and frequency control in a half-center locomotor CPG. Journal of neurophysiology. 119 [PubMed]

Bacak BJ, Kim T, Smith JC, Rubin JE, Rybak IA. (2016). Mixed-mode oscillations and population bursting in the pre-Bötzinger complex. eLife. 5 [PubMed]

Baertsch NA, Baertsch HC, Ramirez JM. (2018). The interdependence of excitation and inhibition for the control of dynamic breathing rhythms. Nature communications. 9 [PubMed]

Barnett WH et al. (2018). The Kölliker-Fuse nucleus orchestrates the timing of expiratory abdominal nerve bursting. Journal of neurophysiology. 119 [PubMed]

Bissonnette JM, Knopp SJ. (2008). Effect of inspired oxygen on periodic breathing in methy-CpG-binding protein 2 (Mecp2) deficient mice. Journal of applied physiology (Bethesda, Md. : 1985). 104 [PubMed]

Bissonnette JM, Schaevitz LR, Knopp SJ, Zhou Z. (2014). Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X. Neuroscience. 267 [PubMed]

Butera RJ, Rinzel J, Smith JC. (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons. Journal of neurophysiology. 82 [PubMed]

Chao HT et al. (2010). Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468 [PubMed]

ClinicalTrials gov. (2019). Evaluation of the efficacy, safety, and tolerability of Sarizotan in Rett syndrome with respiratory symptoms https://clinicaltrials.gov/ct2/show/NCT02790034.

Cohen MI. (1971). Switching of the respiratory phases and evoked phrenic responses produced by rostral pontine electrical stimulation. The Journal of physiology. 217 [PubMed]

Connelly CA, Otto-Smith MR, Feldman JL. (1992). Blockade of NMDA receptor-channels by MK-801 alters breathing in adult rats. Brain research. 596 [PubMed]

Danner SM, Shevtsova NA, Frigon A, Rybak IA. (2017). Computational modeling of spinal circuits controlling limb coordination and gaits in quadrupeds. eLife. 6 [PubMed]

Daun S, Rubin JE, Rybak IA. (2009). Control of oscillation periods and phase durations in half-center central pattern generators: a comparative mechanistic analysis. Journal of computational neuroscience. 27 [PubMed]

Del Negro CA, Wilson CG, Butera RJ, Rigatto H, Smith JC. (2002). Periodicity, mixed-mode oscillations, and quasiperiodicity in a rhythm-generating neural network. Biophysical journal. 82 [PubMed]

Dhingra RR, Dutschmann M, Dick TE. (2016). Blockade of dorsolateral pontine 5HT1A receptors destabilizes the respiratory rhythm in C57BL6/J wild-type mice. Respiratory physiology & neurobiology. 226 [PubMed]

Dick TE et al. (2008). Pontine respiratory-modulated activity before and after vagotomy in decerebrate cats. The Journal of physiology. 586 [PubMed]

Dutschmann M, Dick TE. (2012). Pontine mechanisms of respiratory control. Comprehensive Physiology. 2 [PubMed]

Ermentrout B. (2002). Simulating, analyzing, and animating dynamical systems: a guide to XPPAUT for researchers and students.

Ezure K, Tanaka I. (2004). GABA, in some cases together with glycine, is used as the inhibitory transmitter by pump cells in the Hering-Breuer reflex pathway of the rat. Neuroscience. 127 [PubMed]

Ezure K, Tanaka I, Kondo M. (2003). Glycine is used as a transmitter by decrementing expiratory neurons of the ventrolateral medulla in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Ezure K, Tanaka I, Saito Y. (2003). Brainstem and spinal projections of augmenting expiratory neurons in the rat. Neuroscience research. 45 [PubMed]

Garg SK, Lioy DT, Knopp SJ, Bissonnette JM. (2015). Conditional depletion of methyl-CpG-binding protein 2 in astrocytes depresses the hypercapnic ventilatory response in mice. Journal of applied physiology (Bethesda, Md. : 1985). 119 [PubMed]

Getting PA. (1989). Emerging principles governing the operation of neural networks. Annual review of neuroscience. 12 [PubMed]

Guyenet PG, Bayliss DA. (2015). Neural Control of Breathing and CO2 Homeostasis. Neuron. 87 [PubMed]

Harris KD et al. (2017). Different roles for inhibition in the rhythm-generating respiratory network. Journal of neurophysiology. 118 [PubMed]

Iturriaga R, Oyarce MP, Dias ACR. (2017). Role of Carotid Body in Intermittent Hypoxia-Related Hypertension. Current hypertension reports. 19 [PubMed]

Izhikevich EM. (2007). Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting.

Julu PO et al. (2008). Cardiorespiratory challenges in Rett's syndrome. Lancet (London, England). 371 [PubMed]

Kline DD, Ogier M, Kunze DL, Katz DM. (2010). Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30 [PubMed]

Koizumi H et al. (2008). Functional imaging, spatial reconstruction, and biophysical analysis of a respiratory motor circuit isolated in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Kron M et al. (2014). A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome. Disease models & mechanisms. 7 [PubMed]

Kubin L, Alheid GF, Zuperku EJ, McCrimmon DR. (2006). Central pathways of pulmonary and lower airway vagal afferents. Journal of applied physiology (Bethesda, Md. : 1985). 101 [PubMed]

Levitt ES, Hunnicutt BJ, Knopp SJ, Williams JT, Bissonnette JM. (2013). A selective 5-HT1a receptor agonist improves respiration in a mouse model of Rett syndrome. Journal of applied physiology (Bethesda, Md. : 1985). 115 [PubMed]

Lindsey BG, Rybak IA, Smith JC. (2012). Computational models and emergent properties of respiratory neural networks. Comprehensive Physiology. 2 [PubMed]

Ling L et al. (2001). Chronic intermittent hypoxia elicits serotonin-dependent plasticity in the central neural control of breathing. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21 [PubMed]

Lioy DT et al. (2011). A role for glia in the progression of Rett's syndrome. Nature. 475 [PubMed]

Manzke T et al. (2010). Serotonin receptor 1A-modulated phosphorylation of glycine receptor a3 controls breathing in mice. The Journal of clinical investigation. 120 [PubMed]

Marchenko V et al. (2016). Perturbations of Respiratory Rhythm and Pattern by Disrupting Synaptic Inhibition within Pre-Bötzinger and Bötzinger Complexes. eNeuro. 3 [PubMed]

Medrihan L et al. (2008). Early defects of GABAergic synapses in the brain stem of a MeCP2 mouse model of Rett syndrome. Journal of neurophysiology. 99 [PubMed]

Molkov YI et al. (2010). Late-expiratory activity: emergence and interactions with the respiratory CpG. Journal of neurophysiology. 104 [PubMed]

Molkov YI, Bacak BJ, Dick TE, Rybak IA. (2013). Control of breathing by interacting pontine and pulmonary feedback loops. Frontiers in neural circuits. 7 [PubMed]

Molkov YI, Bacak BJ, Talpalar AE, Rybak IA. (2015). Mechanisms of left-right coordination in mammalian locomotor pattern generation circuits: a mathematical modeling view. PLoS computational biology. 11 [PubMed]

Molkov YI, Rubin JE, Rybak IA, Smith JC. (2017). Computational models of the neural control of breathing. Wiley interdisciplinary reviews. Systems biology and medicine. 9 [PubMed]

Molkov YI et al. (2014). A closed-loop model of the respiratory system: focus on hypercapnia and active expiration. PloS one. 9 [PubMed]

Monteau R, Gauthier P, Rega P, Hilaire G. (1990). Effects of N-methyl-D-aspartate (NMDA) antagonist MK-801 on breathing pattern in rats. Neuroscience letters. 109 [PubMed]

Mörschel M, Dutschmann M. (2009). Pontine respiratory activity involved in inspiratory/expiratory phase transition. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 364 [PubMed]

Okazaki M, Takeda R, Yamazaki H, Haji A. (2002). Synaptic mechanisms of inspiratory off-switching evoked by pontine pneumotaxic stimulation in cats. Neuroscience research. 44 [PubMed]

Poon CS, Song G. (2014). Bidirectional plasticity of pontine pneumotaxic postinspiratory drive: implication for a pontomedullary respiratory central pattern generator. Progress in brain research. 209 [PubMed]

Ramirez JM, Baertsch NA. (2018). The Dynamic Basis of Respiratory Rhythm Generation: One Breath at a Time. Annual review of neuroscience. 41 [PubMed]

Richter DW, Manzke T, Wilken B, Ponimaskin E. (2003). Serotonin receptors: guardians of stable breathing. Trends in molecular medicine. 9 [PubMed]

Rinzel J, Wang XJ. (1992). Alternating and synchronous rhythms in reciprocally inhibitory model neurons Neural Comput. 4

Rojas PS, Fiedler JL. (2016). What Do We Really Know About 5-HT1A Receptor Signaling in Neuronal Cells? Frontiers in cellular neuroscience. 10 [PubMed]

Rubin JE et al. (2011). Interacting oscillations in neural control of breathing: modeling and qualitative analysis. Journal of computational neuroscience. 30 [PubMed]

Rubin JE, Shevtsova NA, Ermentrout GB, Smith JC, Rybak IA. (2009). Multiple rhythmic states in a model of the respiratory central pattern generator. Journal of neurophysiology. 101 [PubMed]

Rybak IA, Abdala AP, Markin SN, Paton JF, Smith JC. (2007). Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation. Progress in brain research. 165 [PubMed]

Rybak IA et al. (2008). Reconfiguration of the pontomedullary respiratory network: a computational modeling study with coordinated in vivo experiments. Journal of neurophysiology. 100 [PubMed]

Samaco RC et al. (2009). Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities. Proceedings of the National Academy of Sciences of the United States of America. 106 [PubMed]

Shevtsova NA et al. (2011). Computational modelling of 5-HT receptor-mediated reorganization of the brainstem respiratory network. The European journal of neuroscience. 34 [PubMed]

Skinner FK, Kopell N, Marder E. (1994). Mechanisms for oscillation and frequency control in reciprocally inhibitory model neural networks. Journal of computational neuroscience. 1 [PubMed]

Smith JC, Abdala AP, Borgmann A, Rybak IA, Paton JF. (2013). Brainstem respiratory networks: building blocks and microcircuits. Trends in neurosciences. 36 [PubMed]

Smith JC, Abdala AP, Koizumi H, Rybak IA, Paton JF. (2007). Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms. Journal of neurophysiology. 98 [PubMed]

Song G, Tin C, Poon CS. (2015). Multiscale fingerprinting of neuronal functional connectivity. Brain structure & function. 220 [PubMed]

Southall DP et al. (1988). Hyperventilation in the awake state: potentially treatable component of Rett syndrome. Archives of disease in childhood. 63 [PubMed]

Stettner GM et al. (2007). Breathing dysfunctions associated with impaired control of postinspiratory activity in Mecp2-/y knockout mice. The Journal of physiology. 579 [PubMed]

Toward MA, Abdala AP, Knopp SJ, Paton JF, Bissonnette JM. (2013). Increasing brain serotonin corrects CO2 chemosensitivity in methyl-CpG-binding protein 2 (Mecp2)-deficient mice. Experimental physiology. 98 [PubMed]

Turovsky E, Karagiannis A, Abdala AP, Gourine AV. (2015). Impaired CO2 sensitivity of astrocytes in a mouse model of Rett syndrome. The Journal of physiology. 593 [PubMed]

Ure K et al. (2016). Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome. eLife. 5 [PubMed]

Viemari JC et al. (2005). Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Weese-Mayer DE et al. (2008). Autonomic dysregulation in young girls with Rett Syndrome during nighttime in-home recordings. Pediatric pulmonology. 43 [PubMed]

Weese-Mayer DE et al. (2006). Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome. Pediatric research. 60 [PubMed]

References and models that cite this paper
This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.