Ausborn J, Snyder AC, Shevtsova NA, Rybak IA, Rubin JE. (2018). State-dependent rhythmogenesis and frequency control in a half-center locomotor CPG. Journal of neurophysiology. 119 [PubMed]

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References and models cited by this paper

Armstrong DM. (1988). The supraspinal control of mammalian locomotion. The Journal of physiology. 405 [PubMed]

Atsuta Y, Garcia-Rill E, Skinner RD. (1990). Characteristics of electrically induced locomotion in rat in vitro brain stem-spinal cord preparation. Journal of neurophysiology. 64 [PubMed]

Barrière G, Frigon A, Leblond H, Provencher J, Rossignol S. (2010). Dual spinal lesion paradigm in the cat: evolution of the kinematic locomotor pattern. Journal of neurophysiology. 104 [PubMed]

Britz O et al. (2015). A genetically defined asymmetry underlies the inhibitory control of flexor-extensor locomotor movements. eLife. 4 [PubMed]

Brocard F et al. (2013). Activity-dependent changes in extracellular Ca2+ and K+ reveal pacemakers in the spinal locomotor-related network. Neuron. 77 [PubMed]

Brocard F, Tazerart S, Vinay L. (2010). Do pacemakers drive the central pattern generator for locomotion in mammals? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 16 [PubMed]

Brown TG. (1914). On the nature of the fundamental activity of the nervous centres, together with an analysis of the conditioning of rhythmic activity in progression, and a theory of evolution of function in the nervous system J Physiol. 48

Burke RE, Degtyarenko AM, Simon ES. (2001). Patterns of locomotor drive to motoneurons and last-order interneurons: clues to the structure of the CPG. Journal of neurophysiology. 86 [PubMed]

Butera RJ, Rinzel J, Smith JC. (1999). Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons. Journal of neurophysiology. 82 [PubMed]

Danner SM, Shevtsova NA, Frigon A, Rybak IA. (2017). Computational modeling of spinal circuits controlling limb coordination and gaits in quadrupeds. eLife. 6 [PubMed]

Danner SM, Wilshin SD, Shevtsova NA, Rybak IA. (2016). Central control of interlimb coordination and speed-dependent gait expression in quadrupeds. The Journal of physiology. 594 [PubMed]

Daun S, Rubin JE, Rybak IA. (2009). Control of oscillation periods and phase durations in half-center central pattern generators: a comparative mechanistic analysis. Journal of computational neuroscience. 27 [PubMed]

Dougherty KJ et al. (2013). Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron. 80 [PubMed]

Duysens J. (2006). How deletions in a model could help explain deletions in the laboratory. Journal of neurophysiology. 95 [PubMed]

Duysens J, De Groote F, Jonkers I. (2013). The flexion synergy, mother of all synergies and father of new models of gait. Frontiers in computational neuroscience. 7 [PubMed]

Ermentrout GB. (1994). Reduction of conductance based models with slow synapses to neural networks. Neural Computation. 6

Ermentrout GB. (2002). Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students Society for Industrial and Applied Mathematics (SIAM).

Frigon A. (2012). Central pattern generators of the mammalian spinal cord. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 18 [PubMed]

Frigon A, Gossard JP. (2009). Asymmetric control of cycle period by the spinal locomotor rhythm generator in the adult cat. The Journal of physiology. 587 [PubMed]

Frigon A et al. (2013). Split-belt walking alters the relationship between locomotor phases and cycle duration across speeds in intact and chronic spinalized adult cats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33 [PubMed]

Gossard JP, Dubuc R, Kolta A. (2011). Preface. Breathe, walk and chew: the neural challenge: part II. Progress in brain research. 188 [PubMed]

Grillner S. (1985). Neurobiological bases of rhythmic motor acts in vertebrates. Science (New York, N.Y.). 228 [PubMed]

Grillner S. (2006). Biological pattern generation: the cellular and computational logic of networks in motion. Neuron. 52 [PubMed]

Halbertsma JM. (1983). The stride cycle of the cat: the modelling of locomotion by computerized analysis of automatic recordings. Acta physiologica Scandinavica. Supplementum. 521 [PubMed]

Hägglund M et al. (2013). Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion. Proceedings of the National Academy of Sciences of the United States of America. 110 [PubMed]

Jankowska E, Jukes MG, Lund S, Lundberg A. (1967). The effect of DOPA on the spinal cord. 6. Half-centre organization of interneurones transmitting effects from the flexor reflex afferents. Acta physiologica Scandinavica. 70 [PubMed]

Jankowska E, Jukes MG, Lund S, Lundberg A. (1967). The effect of DOPA on the spinal cord. 5. Reciprocal organization of pathways transmitting excitatory action to alpha motoneurones of flexors and extensors. Acta physiologica Scandinavica. 70 [PubMed]

Jasinski PE, Molkov YI, Shevtsova NA, Smith JC, Rybak IA. (2013). Sodium and calcium mechanisms of rhythmic bursting in excitatory neural networks of the pre-Bötzinger complex: a computational modelling study. The European journal of neuroscience. 37 [PubMed]

Juvin L, Simmers J, Morin D. (2007). Locomotor rhythmogenesis in the isolated rat spinal cord: a phase-coupled set of symmetrical flexion extension oscillators. The Journal of physiology. 583 [PubMed]

Kriellaars DJ, Brownstone RM, Noga BR, Jordan LM. (1994). Mechanical entrainment of fictive locomotion in the decerebrate cat. Journal of neurophysiology. 71 [PubMed]

Lafreniere-Roula M, McCrea DA. (2005). Deletions of rhythmic motoneuron activity during fictive locomotion and scratch provide clues to the organization of the mammalian central pattern generator. Journal of neurophysiology. 94 [PubMed]

Lundberg A. (1981). Half-centres revisited.Regulatory Functions of the CNS: Principles of Motion and Organization.

Machado TA, Pnevmatikakis E, Paninski L, Jessell TM, Miri A. (2015). Primacy of Flexor Locomotor Pattern Revealed by Ancestral Reversion of Motor Neuron Identity. Cell. 162 [PubMed]

Markin SN et al. (2010). Afferent control of locomotor CPG: insights from a simple neuromechanical model. Annals of the New York Academy of Sciences. 1198 [PubMed]

McCrea DA, Rybak IA. (2007). Modeling the mammalian locomotor CPG: insights from mistakes and perturbations. Progress in brain research. 165 [PubMed]

McCrea DA, Rybak IA. (2008). Organization of mammalian locomotor rhythm and pattern generation. Brain research reviews. 57 [PubMed]

Molkov YI, Bacak BJ, Talpalar AE, Rybak IA. (2015). Mechanisms of left-right coordination in mammalian locomotor pattern generation circuits: a mathematical modeling view. PLoS computational biology. 11 [PubMed]

Musselman KE, Yang JF. (2007). Loading the limb during rhythmic leg movements lengthens the duration of both flexion and extension in human infants. Journal of neurophysiology. 97 [PubMed]

Orlovskiĭ GN, Severin FV, Shik ML. (1966). [Locomotion induced by stimulation of the mesencephalon]. Doklady Akademii nauk SSSR. 169 [PubMed]

Pearson . (1976). Function of segmental reflexes in the control of stepping in cockroaches and cats Neural Control of Locomotion.

Rinzel J, Wang XJ. (1992). Alternating and synchronous rhythms in reciprocally inhibitory model neurons Neural Comput. 4

Rybak IA, Dougherty KJ, Shevtsova NA. (2015). Organization of the Mammalian Locomotor CPG: Review of Computational Model and Circuit Architectures Based on Genetically Identified Spinal Interneurons(1,2,3). eNeuro. 2 [PubMed]

Rybak IA, Molkov YI, Jasinski PE, Shevtsova NA, Smith JC. (2014). Rhythmic bursting in the pre-Bötzinger complex: mechanisms and models. Progress in brain research. 209 [PubMed]

Rybak IA, Shevtsova NA, Kiehn O. (2013). Modelling genetic reorganization in the mouse spinal cord affecting left-right coordination during locomotion. The Journal of physiology. 591 [PubMed]

Rybak IA, Shevtsova NA, Lafreniere-Roula M, McCrea DA. (2006). Modelling spinal circuitry involved in locomotor pattern generation: insights from deletions during fictive locomotion. The Journal of physiology. 577 [PubMed]

Rybak IA, Shevtsova NA, Ptak K, McCrimmon DR. (2004). Intrinsic bursting activity in the pre-Bötzinger complex: role of persistent sodium and potassium currents. Biological cybernetics. 90 [PubMed]

Rybak IA, Shevtsova NA, St-John WM, Paton JF, Pierrefiche O. (2003). Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studies. The European journal of neuroscience. 18 [PubMed]

Rybak IA, Stecina K, Shevtsova NA, McCrea DA. (2006). Modelling spinal circuitry involved in locomotor pattern generation: insights from the effects of afferent stimulation. The Journal of physiology. 577 [PubMed]

Sherwood WE, Harris-Warrick R, Guckenheimer J. (2011). Synaptic patterning of left-right alternation in a computational model of the rodent hindlimb central pattern generator. Journal of computational neuroscience. 30 [PubMed]

Shevtsova NA, Rybak IA. (2016). Organization of flexor-extensor interactions in the mammalian spinal cord: insights from computational modelling. The Journal of physiology. 594 [PubMed]

Shevtsova NA et al. (2015). Organization of left-right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling. The Journal of physiology. 593 [PubMed]

Shik ML, Severin FV, Orlovskiĭ GN. (1966). [Control of walking and running by means of electric stimulation of the midbrain]. Biofizika. 11 [PubMed]

Shpiro A, Curtu R, Rinzel J, Rubin N. (2007). Dynamical characteristics common to neuronal competition models. Journal of neurophysiology. 97 [PubMed]

Skinner FK, Turrigiano GG, Marder E. (1993). Frequency and burst duration in oscillating neurons and two-cell networks. Biological cybernetics. 69 [PubMed]

Skinner RD, Garcia-Rill E. (1984). The mesencephalic locomotor region (MLR) in the rat. Brain research. 323 [PubMed]

Smith JC et al. (2000). Respiratory rhythm generation in neonatal and adult mammals: the hybrid pacemaker-network model. Respiration physiology. 122 [PubMed]

Smith JC, Terman D, Butera RJ, Rubin J. (2005). Oscillatory bursting mechanisms in respiratory pacemaker neurons and networks Bursting: The Genesis of Rhythm in the Nervous System.

Sobinov A, Yakovenko S. (2018). Model of a bilateral Brown-type central pattern generator for symmetric and asymmetric locomotion. Journal of neurophysiology. 119 [PubMed]

Stuart DG, Hultborn H. (2008). Thomas Graham Brown (1882--1965), Anders Lundberg (1920-), and the neural control of stepping. Brain research reviews. 59 [PubMed]

Talpalar AE et al. (2013). Dual-mode operation of neuronal networks involved in left-right alternation. Nature. 500 [PubMed]

Tazerart S, Viemari JC, Darbon P, Vinay L, Brocard F. (2007). Contribution of persistent sodium current to locomotor pattern generation in neonatal rats. Journal of neurophysiology. 98 [PubMed]

Tazerart S, Vinay L, Brocard F. (2008). The persistent sodium current generates pacemaker activities in the central pattern generator for locomotion and regulates the locomotor rhythm. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Terman D, Rubin J. (2002). Synchronized activity and loss of synchrony among heterogeneous conditional oscillators SIAM J Appl Dyn Syst. 1

Terman D, Rubin J, Wechselberger M, Borisyuk A, Best J. (2005). The dynamic range of bursting in a model respiratory pacemaker network Siam J App Dyn Sys. 4

Yakovenko S. (2011). Chapter 10--a hierarchical perspective on rhythm generation for locomotor control. Progress in brain research. 188 [PubMed]

Yakovenko S, McCrea DA, Stecina K, Prochazka A. (2005). Control of locomotor cycle durations. Journal of neurophysiology. 94 [PubMed]

Zhang J et al. (2014). V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. Neuron. 82 [PubMed]

Zhong G, Masino MA, Harris-Warrick RM. (2007). Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Zhong G, Shevtsova NA, Rybak IA, Harris-Warrick RM. (2012). Neuronal activity in the isolated mouse spinal cord during spontaneous deletions in fictive locomotion: insights into locomotor central pattern generator organization. The Journal of physiology. 590 [PubMed]

Ziskind-Conhaim L, Wu L, Wiesner EP. (2008). Persistent sodium current contributes to induced voltage oscillations in locomotor-related hb9 interneurons in the mouse spinal cord. Journal of neurophysiology. 100 [PubMed]

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