DBS of a multi-compartment model of subthalamic nucleus projection neurons (Miocinovic et al. 2006)


Miocinovic S et al. (2006). Computational analysis of subthalamic nucleus and lenticular fasciculus activation during therapeutic deep brain stimulation. Journal of neurophysiology. 96 [PubMed]

See more from authors: Miocinovic S · Parent M · Butson CR · Hahn PJ · Russo GS · Vitek JL · McIntyre CC

References and models cited by this paper

Anderson TR, Hu B, Iremonger K, Kiss ZH. (2006). Selective attenuation of afferent synaptic transmission as a mechanism of thalamic deep brain stimulation-induced tremor arrest. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26 [PubMed]

Baldissera F, Lundberg A, Udo M. (1972). Stimulation of pre- and postsynaptic elements in the red nucleus. Experimental brain research. 15 [PubMed]

Bar-Gad I, Elias S, Vaadia E, Bergman H. (2004). Complex locking rather than complete cessation of neuronal activity in the globus pallidus of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primate in response to pallidal microstimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]

Beurrier C, Bioulac B, Audin J, Hammond C. (2001). High-frequency stimulation produces a transient blockade of voltage-gated currents in subthalamic neurons. Journal of neurophysiology. 85 [PubMed]

Beurrier C, Congar P, Bioulac B, Hammond C. (1999). Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Bevan MD, Wilson CJ. (1999). Mechanisms underlying spontaneous oscillation and rhythmic firing in rat subthalamic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19 [PubMed]

Bookstein FL. (1990). Morphometrics Three-dimensional Neuroimaging.

Bowden DM, Martin RF. (2000). Primate Brain Maps: Structure of the Macaque Brain.

Burchiel KJ, Anderson VC, Favre J, Hammerstad JP. (1999). Comparison of pallidal and subthalamic nucleus deep brain stimulation for advanced Parkinson's disease: results of a randomized, blinded pilot study. Neurosurgery. 45 [PubMed]

Butson CR, Maks CB, McIntyre CC. (2006). Sources and effects of electrode impedance during deep brain stimulation. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 117 [PubMed]

Butson CR, McIntyre CC. (2005). Tissue and electrode capacitance reduce neural activation volumes during deep brain stimulation. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 116 [PubMed]

Deep-Brain Stimulation for Parkinson's Disease Study Group et al. (2001). Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease. The New England journal of medicine. 345 [PubMed]

Destexhe A, Mainen ZF, Sejnowski TJ. (1994). Synthesis of models for excitable membranes, synaptic transmission and neuromodulation using a common kinetic formalism. Journal of computational neuroscience. 1 [PubMed]

Do MT, Bean BP. (2003). Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation. Neuron. 39 [PubMed]

Dostrovsky JO et al. (2000). Microstimulation-induced inhibition of neuronal firing in human globus pallidus. Journal of neurophysiology. 84 [PubMed]

Elder CM, Hashimoto T, Zhang J, Vitek JL. (2005). Chronic implantation of deep brain stimulation leads in animal models of neurological disorders. Journal of neuroscience methods. 142 [PubMed]

Filali M, Hutchison WD, Palter VN, Lozano AM, Dostrovsky JO. (2004). Stimulation-induced inhibition of neuronal firing in human subthalamic nucleus. Experimental brain research. 156 [PubMed]

Gillies A, Willshaw D. (2006). Membrane channel interactions underlying rat subthalamic projection neuron rhythmic and bursting activity. Journal of neurophysiology. 95 [PubMed]

Grill WM, Mortimer JT. (1994). Electrical properties of implant encapsulation tissue. Annals of biomedical engineering. 22 [PubMed]

Grill WM, Snyder AN, Miocinovic S. (2004). Deep brain stimulation creates an informational lesion of the stimulated nucleus. Neuroreport. 15 [PubMed]

Gustafsson B, Jankowska E. (1976). Direct and indirect activation of nerve cells by electrical pulses applied extracellularly. The Journal of physiology. 258 [PubMed]

Hamel W et al. (2003). Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: evaluation of active electrode contacts. Journal of neurology, neurosurgery, and psychiatry. 74 [PubMed]

Hashimoto T, Elder CM, Okun MS, Patrick SK, Vitek JL. (2003). Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23 [PubMed]

Hashimoto T, Elder CM, Vitek JL. (2002). A template subtraction method for stimulus artifact removal in high-frequency deep brain stimulation. Journal of neuroscience methods. 113 [PubMed]

Herzog J et al. (2004). Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. 19 [PubMed]

Hines ML, Carnevale NT. (1997). The NEURON simulation environment. Neural computation. 9 [PubMed]

Kim R, Nakano K, Jayaraman A, Carpenter MB. (1976). Projections of the globus pallidus and adjacent structures: an autoradiographic study in the monkey. The Journal of comparative neurology. 169 [PubMed]

Kita H, Chang HT, Kitai ST. (1983). Pallidal inputs to subthalamus: intracellular analysis. Brain research. 264 [PubMed]

Krack P et al. (2003). Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. The New England journal of medicine. 349 [PubMed]

Kuo JS, Carpenter MB. (1973). Organization of pallidothalamic projections in the rhesus monkey. The Journal of comparative neurology. 151 [PubMed]

Lee KH et al. (2006). Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: potential mechanism of action in Parkinson's disease. The European journal of neuroscience. 23 [PubMed]

Limousin P et al. (1998). Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. The New England journal of medicine. 339 [PubMed]

McIntyre CC, Grill WM. (1999). Excitation of central nervous system neurons by nonuniform electric fields. Biophysical journal. 76 [PubMed]

McIntyre CC, Grill WM. (2000). Selective microstimulation of central nervous system neurons. Annals of biomedical engineering. 28 [PubMed]

McIntyre CC, Grill WM, Sherman DL, Thakor NV. (2004). Cellular effects of deep brain stimulation: model-based analysis of activation and inhibition. Journal of neurophysiology. 91 [PubMed]

McIntyre CC, Mori S, Sherman DL, Thakor NV, Vitek JL. (2004). Electric field and stimulating influence generated by deep brain stimulation of the subthalamic nucleus. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 115 [PubMed]

McIntyre CC, Parent A, Miocinovic S, Parent M. (2004). Electrical stimulation of the subthalamic nucleus: model-based analysis of a 3D reconstructed neuron to intracellular and extracellular stimulation Soc Neurosci Abstr 70.27.

McIntyre CC, Richardson AG, Grill WM. (2002). Modeling the excitability of mammalian nerve fibers: influence of afterpotentials on the recovery cycle. Journal of neurophysiology. 87 [PubMed]

Meissner W et al. (2005). Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations. Brain : a journal of neurology. 128 [PubMed]

Montgomery EB, Baker KB. (2000). Mechanisms of deep brain stimulation and future technical developments. Neurological research. 22 [PubMed]

Nakanishi H, Kita H, Kitai ST. (1987). Electrical membrane properties of rat subthalamic neurons in an in vitro slice preparation. Brain research. 437 [PubMed]

Nowak LG, Bullier J. (1998). Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter. II. Evidence from selective inactivation of cell bodies and axon initial segments. Experimental brain research. 118 [PubMed]

Nowinski WL, Belov D, Pollak P, Benabid AL. (2005). Statistical analysis of 168 bilateral subthalamic nucleus implantations by means of the probabilistic functional atlas. Neurosurgery. 57 [PubMed]

Okun MS et al. (2005). Management of referred deep brain stimulation failures: a retrospective analysis from 2 movement disorders centers. Archives of neurology. 62 [PubMed]

Otsuka T, Abe T, Tsukagawa T, Song WJ. (2004). Conductance-based model of the voltage-dependent generation of a plateau potential in subthalamic neurons. Journal of neurophysiology. 92 [PubMed]

Parent M, Lévesque M, Parent A. (2001). Two types of projection neurons in the internal pallidum of primates: single-axon tracing and three-dimensional reconstruction. The Journal of comparative neurology. 439 [PubMed]

Parent M, Parent A. (2004). The pallidofugal motor fiber system in primates. Parkinsonism & related disorders. 10 [PubMed]

RANCK JB. (1963). Specific impedance of rabbit cerebral cortex. Experimental neurology. 7 [PubMed]

Ranck JB. (1975). Which elements are excited in electrical stimulation of mammalian central nervous system: a review. Brain research. 98 [PubMed]

Rizzone M et al. (2001). Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: effects of variation in stimulation parameters. Journal of neurology, neurosurgery, and psychiatry. 71 [PubMed]

Rodriguez-Oroz MC et al. (2005). Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up. Brain : a journal of neurology. 128 [PubMed]

Rubin JE, Terman D. (2004). High frequency stimulation of the subthalamic nucleus eliminates pathological thalamic rhythmicity in a computational model. Journal of computational neuroscience. 16 [PubMed]

Saint-Cyr JA et al. (2002). Localization of clinically effective stimulating electrodes in the human subthalamic nucleus on magnetic resonance imaging. Journal of neurosurgery. 97 [PubMed]

Sato F, Parent M, Levesque M, Parent A. (2000). Axonal branching pattern of neurons of the subthalamic nucleus in primates. The Journal of comparative neurology. 424 [PubMed]

Sejnowski TJ, Destexhe A, Mainen Z. (1994). An efficient method for computing synaptic conductances based on a kinetic model of receptor binding Neural Comput. 6

Smith Y, Bolam JP, Von Krosigk M. (1990). Topographical and Synaptic Organization of the GABA-Containing Pallidosubthalamic Projection in the Rat. The European journal of neuroscience. 2 [PubMed]

Starr PA et al. (2002). Implantation of deep brain stimulators into the subthalamic nucleus: technical approach and magnetic resonance imaging-verified lead locations. Journal of neurosurgery. 97 [PubMed]

Tehovnik EJ. (1996). Electrical stimulation of neural tissue to evoke behavioral responses. Journal of neuroscience methods. 65 [PubMed]

Temperli P et al. (2003). How do parkinsonian signs return after discontinuation of subthalamic DBS? Neurology. 60 [PubMed]

Terman D, Rubin JE, Yew AC, Wilson CJ. (2002). Activity patterns in a model for the subthalamopallidal network of the basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22 [PubMed]

Voges J et al. (2002). Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position. Journal of neurosurgery. 96 [PubMed]

Volkmann J, Herzog J, Kopper F, Deuschl G. (2002). Introduction to the programming of deep brain stimulators. Movement disorders : official journal of the Movement Disorder Society. 17 Suppl 3 [PubMed]

Walter BL, Vitek JL. (2004). Surgical treatment for Parkinson's disease. The Lancet. Neurology. 3 [PubMed]

Welter ML et al. (2004). Effects of high-frequency stimulation on subthalamic neuronal activity in parkinsonian patients. Archives of neurology. 61 [PubMed]

Wichmann T, Kliem MA, Soares J. (2002). Slow oscillatory discharge in the primate basal ganglia. Journal of neurophysiology. 87 [PubMed]

Wilson CJ, Weyrick A, Terman D, Hallworth NE, Bevan MD. (2004). A model of reverse spike frequency adaptation and repetitive firing of subthalamic nucleus neurons. Journal of neurophysiology. 91 [PubMed]

Yelnik J et al. (2003). Localization of stimulating electrodes in patients with Parkinson disease by using a three-dimensional atlas-magnetic resonance imaging coregistration method. Journal of neurosurgery. 99 [PubMed]

Zonenshayn M, Sterio D, Kelly PJ, Rezai AR, Beric A. (2004). Location of the active contact within the subthalamic nucleus (STN) in the treatment of idiopathic Parkinson's disease. Surgical neurology. 62 [PubMed]

References and models that cite this paper

Bellinger SC, Miyazawa G, Steinmetz PN. (2008). Submyelin potassium accumulation may functionally block subsets of local axons during deep brain stimulation: a modeling study. Journal of neural engineering. 5 [PubMed]

Farokhniaee A, McIntyre CC. (2019). Theoretical principles of deep brain stimulation induced synaptic suppression. Brain stimulation. 12 [PubMed]

Hahn PJ, McIntyre CC. (2010). Modeling shifts in the rate and pattern of subthalamopallidal network activity during deep brain stimulation. Journal of computational neuroscience. 28 [PubMed]

Johnson MD, McIntyre CC. (2008). Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation. Journal of neurophysiology. 100 [PubMed]

Maling N, Lempka SF, Blumenfeld Z, Bronte-Stewart H, McIntyre CC. (2018). Biophysical basis of subthalamic local field potentials recorded from deep brain stimulation electrodes. Journal of neurophysiology. 120 [PubMed]

So RQ, Kent AR, Grill WM. (2012). Relative contributions of local cell and passing fiber activation and silencing to changes in thalamic fidelity during deep brain stimulation and lesioning: a computational modeling study. Journal of computational neuroscience. 32 [PubMed]

Yi G, Grill WM. (2018). Frequency-dependent antidromic activation in thalamocortical relay neurons: effects of synaptic inputs. Journal of neural engineering. 15 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.