Winslow RL, Cortassa S, Greenstein JL. (2005). Using models of the myocyte for functional interpretation of cardiac proteomic data. The Journal of physiology. 563 [PubMed]

See more from authors: Winslow RL · Cortassa S · Greenstein JL

References and models cited by this paper

Alseikhan BA, DeMaria CD, Colecraft HM, Yue DT. (2002). Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation. Proceedings of the National Academy of Sciences of the United States of America. 99 [PubMed]

Beuckelmann DJ, Erdmann E. (1992). Ca(2+)-currents and intracellular [Ca2+]i-transients in single ventricular myocytes isolated from terminally failing human myocardium. Basic research in cardiology. 87 Suppl 1 [PubMed]

Beuckelmann DJ, Näbauer M, Erdmann E. (1993). Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure. Circulation research. 73 [PubMed]

Chen-Izu Y et al. (2000). G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophysical journal. 79 [PubMed]

Cheng H, Kuschel M, Lakatta EG, Xiao R-P, Zhou YY. (1999). Recent advances in cardiac 2-adrenergic signal transduction Circ Res. 85

Cheng H, Lederer WJ, Cannell MB. (1993). Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science (New York, N.Y.). 262 [PubMed]

Cortassa S, Aon MA, Marbán E, Winslow RL, O'Rourke B. (2003). An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophysical journal. 84 [PubMed]

Davare MA et al. (2001). A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2. Science (New York, N.Y.). 293 [PubMed]

DiFrancesco D, Noble D. (1985). A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 307 [PubMed]

Franzini-Armstrong C, Protasi F, Ramesh V. (1999). Shape, size, and distribution of Ca(2+) release units and couplons in skeletal and cardiac muscles. Biophysical journal. 77 [PubMed]

Ginsburg KS, Bers DM. (2004). Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger. The Journal of physiology. 556 [PubMed]

Greenstein JL, Tanskanen AJ, Winslow RL. (2004). Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes. Annals of the New York Academy of Sciences. 1015 [PubMed]

Greenstein JL, Winslow RL. (2002). An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophysical journal. 83 [PubMed]

Greenstein JL, Wu R, Po S, Tomaselli GF, Winslow RL. (2000). Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circulation research. 87 [PubMed]

Herzig S, Patil P, Neumann J, Staschen CM, Yue DT. (1993). Mechanisms of beta-adrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating. Biophysical journal. 65 [PubMed]

Irvine LA, Jafri MS, Winslow RL. (1999). Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation. Biophysical journal. 76 [PubMed]

Iyer V, Mazhari R, Winslow RL. (2004). A computational model of the human left-ventricular epicardial myocyte. Biophysical journal. 87 [PubMed]

Jafri MS, Rice JJ, Winslow RL. (1998). Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophysical journal. 74 [PubMed]

Kääb S et al. (1996). Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circulation research. 78 [PubMed]

Luo CH, Rudy Y. (1994). A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circulation research. 74 [PubMed]

Mazhari R, Greenstein JL, Winslow RL, Marbán E, Nuss HB. (2001). Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circulation research. 89 [PubMed]

NOBLE D. (1960). Cardiac action and pacemaker potentials based on the Hodgkin-Huxley equations. Nature. 188 [PubMed]

Näbauer M, Beuckelmann DJ, Uberfuhr P, Steinbeck G. (1996). Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation. 93 [PubMed]

O'Rourke B et al. (1999). Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies. Circulation research. 84 [PubMed]

Peterson BZ, DeMaria CD, Adelman JP, Yue DT. (1999). Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels. Neuron. 22 [PubMed]

Peterson BZ et al. (2000). Critical determinants of Ca(2+)-dependent inactivation within an EF-hand motif of L-type Ca(2+) channels. Biophysical journal. 78 [PubMed]

Puglisi JL, Bers DM. (2001). LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport. American journal of physiology. Cell physiology. 281 [PubMed]

Rice JJ, Jafri MS, Winslow RL. (2000). Modeling short-term interval-force relations in cardiac muscle. American journal of physiology. Heart and circulatory physiology. 278 [PubMed]

Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD. (2003). Modeling beta-adrenergic control of cardiac myocyte contractility in silico. The Journal of biological chemistry. 278 [PubMed]

Shacklock PS, Wier WG, Balke CW. (1995). Local Ca2+ transients (Ca2+ sparks) originate at transverse tubules in rat heart cells. The Journal of physiology. 487 ( Pt 3) [PubMed]

Sham JS, Cleemann L, Morad M. (1995). Functional coupling of Ca2+ channels and ryanodine receptors in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 92 [PubMed]

Spurgeon H, Song L-S, Wang S-Q, Xiao R-P, Lakatta_eg CHENG_H. (2001). Beta-Adrenergic stimulation synchronizes intracellular Ca2+ release during excitation-contraction coupling in cardiac myocytes Circ Res. 88

Stern MD. (1992). Theory of excitation-contraction coupling in cardiac muscle. Biophysical journal. 63 [PubMed]

Tanskanen AJ, Greenstein JL, O'Rourke B, Winslow RL. (2005). The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophysical journal. 88 [PubMed]

Wang SQ, Song LS, Lakatta EG, Cheng H. (2001). Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature. 410 [PubMed]

Wier WG, Egan TM, López-López JR, Balke CW. (1994). Local control of excitation-contraction coupling in rat heart cells. The Journal of physiology. 474 [PubMed]

Winslow RL, Greenstein JL, Tomaselli GF, ORourke B. (2001). Computational models of the failing myocyte: relating altered gene expression to cellular function Phil Trans R Soc Lond A. 359

Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B. (1999). Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circulation research. 84 [PubMed]

Yue DT, Herzig S, Marban E. (1990). Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proceedings of the National Academy of Sciences of the United States of America. 87 [PubMed]

References and models that cite this paper

Patel SP, Campbell DL. (2005). Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms. The Journal of physiology. 569 [PubMed]

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